Chemotherapeutic Agents in Noncytotoxic Concentrations Increase Antigen Presentation by Dendritic Cells via an IL-12-Dependent Mechanism

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

2007 • 2,814 citations

Calreticulin exposure dictates the immunogenicity of cancer cell death

2006 • 2,789 citations

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

2005 • 1,330 citations

Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity

2005 • 1,010 citations

T-cell priming by type-1and type-2 polarized dendritic cells: the concept of a third signal

1999 • 957 citations

Inhibition of CD4+25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

2005 • 878 citations

CD4⁺CD25⁺ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative

2004 • 854 citations

Immunotherapy and chemotherapy — a practical partnership

2005 • 639 citations

Signals required for programming effector and memory development by CD8⁺ T cells

2006 • 574 citations

Progressive differentiation and selection of the fittest in the immune response

2002 • 503 citations

Cancer Immunotherapy by Dendritic Cells

2008 • 501 citations

Signal 3 Determines Tolerance versus Full Activation of Naive CD8 T Cells

2003 • 494 citations

Induction of Tumor Cell Apoptosis In Vivo Increases Tumor Antigen Cross-Presentation, Cross-Priming Rather than Cross-Tolerizing Host Tumor-Specific CD8 T Cells

2003 • 441 citations

Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8+ T cells

2005 • 296 citations

Immunogenic cancer cell death: a key-lock paradigm

2008 • 294 citations

Molecular Interactions between Dying Tumor Cells and the Innate Immune System Determine the Efficacy of Conventional Anticancer Therapies

2008 • 214 citations

Cancer Vaccines: Moving Beyond Current Paradigms

2007 • 213 citations

A Combination of Chemoimmunotherapies Can Efficiently Break Self-Tolerance and Induce Antitumor Immunity in a Tolerogenic Murine Tumor Model

2007 • 201 citations

The Roles of IL-12 in Providing a Third Signal for Clonal Expansion of Naive CD8 T Cells

2002 • 196 citations

Ecto‐calreticulin in immunogenic chemotherapy

2007 • 187 citations

Taming cancer by inducing immunity via dendritic cells

2007 • 185 citations

Leveraging the Activity of Tumor Vaccines with Cytotoxic Chemotherapy

2005 • 180 citations

Single administration of low dose cyclophosphamide augments the antitumor effect of dendritic cell vaccine

2007 • 134 citations

Low-Dose Paclitaxel Prior to Intratumoral Dendritic Cell Vaccine Modulates Intratumoral Cytokine Network and Lung Cancer Growth

2007 • 126 citations

Combined intratumoral injection of bone marrow-derived dendritic cells and systemic chemotherapy to treat pre-existing murine tumors.

2001 • 122 citations

Uric Acid Promotes Tumor Immune Rejection

2004 • 121 citations

Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer.

2003 • 103 citations

Immunogenic anti-cancer chemotherapy as an emerging concept

2008 • 100 citations

Cutting Edge: Bcl-3 Up-Regulation by Signal 3 Cytokine (IL-12) Prolongs Survival of Antigen-Activated CD8 T Cells

2005 • 98 citations

Combined chemoimmunotherapy of solid tumours: Improving vaccines?

2006 • 94 citations

Antigen-Processing Machinery in Human Dendritic Cells: Up-Regulation by Maturation and Down-Regulation by Tumor Cells

2004 • 92 citations

Dendritic cell-based vaccination combined with gemcitabine increases survival in a murine pancreatic carcinoma model

2007 • 84 citations

Recovery of CD8+ T-Cell Function During Systemic Chemotherapy in Advanced Ovarian Cancer

2005 • 82 citations

Restoration by IL-15 of MHC Class I Antigen-Processing Machinery in Human Dendritic Cells Inhibited by Tumor-Derived Gangliosides

2005 • 73 citations

Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all

2007 • 65 citations

A Better Way for a Cancer Cell to Die

2006 • 63 citations

Signal 3 Availability Limits the CD8 T Cell Response to a Solid Tumor

2007 • 61 citations

Nitric Oxide Boosts Chemoimmunotherapy via Inhibition of Acid Sphingomyelinase in a Mouse Model of Melanoma

2007 • 61 citations

Role of conventional treatments on circulating and monocyte-derived dendritic cells in colorectal cancer

2006 • 39 citations

Low-dose Chemotherapeutic Agents Regulate Small Rho GTPase Activity in Dendritic Cells

2008 • 38 citations

Dendritic Cells in Cancer

2009 • 32 citations

Antitumor effect of intratumoral administration of dendritic cell combination with vincristine chemotherapy in a murine fibrosarcoma model.

2003 • 32 citations

GENERATION OF TOLEROGENIC DENDRITIC CELLS BY TREATMENT WITH MITOMYCIN C: INHIBITION OF ALLOGENEIC T-CELL RESPONSE IS MEDIATED BY DOWNREGULATION OF ICAM-1, CD80, AND CD86

2004 • 31 citations

Immunogenicity of Dendritic-Tumor Fusion Hybrids and Their Utility in Cancer Immunotherapy

2007 • 31 citations

Human cultured dendritic cells show differential sensitivity to chemotherapy agents as assessed by the MTS assay

1999 • 28 citations

Protective specific immunity induced by doxorubicin plus TNF-α combination treatment of EL4 lymphoma-bearing C57BL/6 mice

2000 • 27 citations

Effects of docetaxel on antigen presentation-related functions of human monocyte-derived dendritic cells

2005 • 26 citations

Interferon regulatory factor 8 mediates tumor-induced inhibition of antigen processing and presentation by dendritic cells

2008 • 21 citations

Exploiting dendritic cells for active immunotherapy of cancer and chronic infections

2007 • 18 citations

Exploiting Dendritic Cells for Active Immunotherapy of Cancer and Chronic Infection

2004 • 18 citations

Recognition of Live Phosphatidylserine-Labeled Tumor Cells by Dendritic Cells: A Novel Approach to Immunotherapy of Skin Cancer

2009 • 14 citations

Dendritic Cell Regeneration in the Bone Marrow of Children Treated for Acute Lymphoblastic Leukaemia

2007 • 13 citations

Cancer Therapy and Dendritic Cell Immunomodulation

2009 • 9 citations

[Subpopulations of peripheral blood dendritic cells during chemotherapy of ovarian cancer].

2007 • 5 citations

Late dendritic cells are still able to evoke a potent alloreactive CTL response

2007 • 4 citations