Nitric Oxide Boosts Chemoimmunotherapy via Inhibition of Acid Sphingomyelinase in a Mouse Model of Melanoma

Dendritic cells as therapeutic vaccines against cancer

2005 • 1,195 citations

The role of nitric oxide in tumour progression

2006 • 1,181 citations

Persistent inhibition of cell respiration by nitric oxide: Crucial role ofS-nitrosylation of mitochondrial complex I and protective action of glutathione

1998 • 825 citations

Acid sphingomyelinase deficient mice: a model of types A and B Niemann–Pick disease

1995 • 469 citations

Cisplatin-Induced CD95 Redistribution into Membrane Lipid Rafts of HT29 Human Colon Cancer Cells

2004 • 307 citations

Severe immunodeficiency in patients treated with fludarabine monophosphate

1993 • 137 citations

Immunotherapy: Bewitched, Bothered, and Bewildered No More

2004 • 136 citations

Toxicities of the platinum antineoplastic agents

2003 • 132 citations

Nitric Oxide Regulates Cell Sensitivity to Cisplatin-Induced Apoptosis through S-Nitrosylation and Inhibition of Bcl-2 Ubiquitination

2006 • 122 citations

Acid Sphingomyelinase-deficient Macrophages Have Defective Cholesterol Trafficking and Efflux

2001 • 122 citations

Therapeutic cancer vaccines

2006 • 121 citations

Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin

2006 • 96 citations

Activation of Acid Sphingomyelinase and Its Inhibition by the Nitric Oxide/Cyclic Guanosine 3′,5′-Monophosphate Pathway: Key Events in Escherichia coli-Elicited Apoptosis of Dendritic Cells

2004 • 92 citations

Gene Therapy of Cancer Based on Interleukin 12

2005 • 91 citations

Activation of the Endothelial Nitric-oxide Synthase by Tumor Necrosis Factor-α

2001 • 89 citations

The role of nitric oxide chemistry in cancer treatment.

1998 • 80 citations

Sphingolipids as therapeutics

2003 • 69 citations

Ex vivo treatment with nitric oxide increases mesoangioblast therapeutic efficacy in muscular dystrophy

2006 • 60 citations

Nitric oxide donor increases the efficiency of cytostatic therapy and retards the development of drug resistance

2003 • 54 citations

In vivo radiation protection by nitric oxide modulation.

1994 • 52 citations

Nitric Oxide Inhibits the Tumor Necrosis Factor α-regulated Endocytosis of Human Dendritic Cells in a Cyclic GMP-dependent Way

2000 • 51 citations

Nitric Oxide Confers Therapeutic Activity to Dendritic Cells in a Mouse Model of Melanoma

2004 • 45 citations

Nitric Oxide Improves Cisplatin Cytotoxicity in Head and Neck Squamous Cell Carcinoma

2001 • 44 citations

Synergism of nitric oxide and maturation signals on human dendritic cells occurs through a cyclic GMP-dependent pathway

2003 • 40 citations

Lack of ceramide generation and altered sphingolipid composition are associated with drug resistance in human ovarian carcinoma cells

2006 • 38 citations

Murine Dendritic Cell-Induced Tumor Apoptosis is Partially Mediated by Nitric Oxide

2002 • 30 citations

A Cellular System to Study the Role of Nitric Oxide in Cell Death, Survival, and Migration

2005 • 9 citations