Cutting Edge: Bcl-3 Up-Regulation by Signal 3 Cytokine (IL-12) Prolongs Survival of Antigen-Activated CD8 T Cells

Primer3 on the WWW for General Users and for Biologist Programmers

2003 • 15,242 citations

NF-κB regulation in the immune system

2002 • 3,804 citations

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

NF-κB at the crossroads of life and death

2002 • 2,684 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Type I Interferons Keep Activated T Cells Alive

1999 • 769 citations

Inflammatory Cytokines Provide a Third Signal for Activation of Naive CD4+ and CD8+ T Cells

1999 • 580 citations

Activated T Cell Death In Vivo Mediated by Proapoptotic Bcl-2 Family Member Bim

2002 • 564 citations

Signal 3 Determines Tolerance versus Full Activation of Naive CD8 T Cells

2003 • 494 citations

Molecular mechanisms of activated T cell death in vivo

2002 • 276 citations

T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides

1993 • 256 citations

The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner.

1993 • 242 citations

Immunological adjuvants promote activated T cell survival via induction of Bcl-3

2001 • 228 citations

The Roles of IL-12 in Providing a Third Signal for Clonal Expansion of Naive CD8 T Cells

2002 • 196 citations

Critical Roles for the Bcl-3 Oncoprotein in T Cell–Mediated Immunity, Splenic Microarchitecture, and Germinal Center Reactions

1997 • 179 citations

Cell Cycle-Dependent Regulation of FLIP Levels and Susceptibility to Fas-Mediated Apoptosis

1999 • 173 citations

Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal.

1995 • 167 citations

Immunological defects in mice with a targeted disruption in Bcl-3.

1997 • 164 citations

Adjuvant Effect of IL-12: Conversion of Peptide Antigen Administration from Tolerizing to Immunizing for CD8+ T Cells In Vivo

1999 • 138 citations

Peptide Antigen Priming of Naive, But Not Memory, CD8 T Cells Requires a Third Signal That Can Be Provided by IL-12

2002 • 130 citations

Differential regulation of bcl-2 and bcl-x by CD3, CD28, and the IL-2 receptor in cloned CD4+ helper T cells. A model for the long-term survival of memory cells.

1996 • 110 citations

Bystander Virus Infection Prolongs Activated T Cell Survival

1999 • 90 citations

The bcl-3 Proto-Oncogene Encodes a Nuclear IκB-like Molecule That Preferentially Interacts with NF-κB p50 and p52 in a Phosphorylation-Dependent Manner

1993 • 67 citations

Activation of antigen-specific T cells by artificial cell constructs having immobilized multimeric peptide–class I complexes and recombinant B7–Fc proteins

2001 • 49 citations

Inhibition of TCR-Induced CD8 T Cell Death by IL-12: Regulation of Fas Ligand and Cellular FLIP Expression and Caspase Activation by IL-12

2003 • 44 citations

Stronger Correlation of bcl‐3 than bcl‐2, bcl‐x_L, Costimulation, or Antioxidants with Adjuvant‐Induced T Cell Survival

2002 • 25 citations