WNT Signaling Pathway and Stem Cell Signaling Network

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

1999 • 3,566 citations

Generation of a functional mammary gland from a single stem cell

2006 • 1,939 citations

Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

1991 • 1,890 citations

Secreted antagonists of the Wnt signalling pathway

2003 • 1,543 citations

A new member of the frizzled family from Drosophila functions as a Wingless receptor

1996 • 1,489 citations

An LDL-receptor-related protein mediates Wnt signalling in mice

2000 • 1,080 citations

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

2000 • 943 citations

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

2002 • 864 citations

Regulation of osteoblastogenesis and bone mass by Wnt10b

2005 • 853 citations

Dishevelled Activates JNK and Discriminates between JNK Pathways in Planar Polarity and wingless Signaling

1998 • 774 citations

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

2005 • 773 citations

The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway

2003 • 758 citations

Mining the Wnt pathway for cancer therapeutics

2006 • 738 citations

Wnt/Wingless Signaling Requires BCL9/Legless-Mediated Recruitment of Pygopus to the Nuclear β-Catenin-TCF Complex

2002 • 548 citations

The TAK1-NLK Mitogen-Activated Protein Kinase Cascade Functions in the Wnt-5a/Ca²⁺ Pathway To Antagonize Wnt/β-Catenin Signaling

2002 • 540 citations

WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors

1998 • 499 citations

Direct Binding of the PDZ Domain of Dishevelled to a Conserved Internal Sequence in the C-Terminal Region of Frizzled

2003 • 498 citations

A Member of the Frizzled Protein Family Mediating Axis Induction by Wnt-5A

1997 • 493 citations

PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

2004 • 489 citations

Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth

2004 • 462 citations

WNT/PCP signaling pathway and human cancer (Review)

2005 • 408 citations

Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation

2004 • 368 citations

FGF-20 and DKK1 are transcriptional targets of β-catenin and FGF-20 is implicated in cancer and development

2004 • 292 citations

Wg/Wnt Signal Can Be Transmitted through Arrow/LRP5,6 and Axin Independently of Zw3/Gsk3β Activity

2003 • 289 citations

CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling

2006 • 250 citations

Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells

1992 • 246 citations

Cross-talk of WNT and FGF signaling pathways at GSK3ß to regulate ß-catenin and SNAIL signaling cascades

2006 • 245 citations

Functional Interaction between Peroxisome Proliferator-Activated Receptor γ and β-Catenin

2006 • 226 citations

Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

2001 • 214 citations

Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells

2006 • 152 citations

Wnt5b partially inhibits canonical Wnt/β-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes

2005 • 145 citations

Wnt-5a/Ca²⁺-Induced NFAT Activity Is Counteracted by Wnt-5a/Yes-Cdc42-Casein Kinase 1α Signaling in Human Mammary Epithelial Cells

2006 • 142 citations

Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice.

1995 • 119 citations

From Gut Homeostasis to Cancer

2006 • 110 citations

WNT and FGF gene clusters (Review)

2002 • 103 citations

Mechanisms of Disease: from stem cells to colorectal cancer

2006 • 83 citations

Bioinformatics for Cancer Management in the Post-Genome Era

2006 • 42 citations

Identification and characterization of human BCL9L gene and mouse Bcl9l gene in silico

2003 • 38 citations

Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/β-catenin signaling

2005 • 29 citations