Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

1997 • 3,847 citations

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

1999 • 3,566 citations

Wnt signaling and cancer

2000 • 3,215 citations

A simplified system for generating recombinant adenoviruses

1998 • 3,179 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

Wnt signaling: a common theme in animal development

1997 • 2,579 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 • 1,653 citations

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 • 1,531 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1995 • 1,499 citations

Genomic analysis of metastasis reveals an essential role for RhoC

2000 • 1,449 citations

Wnt Signaling in Oncogenesis and Embryogenesis--a Look Outside the Nucleus

2000 • 1,253 citations

Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines

1997 • 1,215 citations

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G ₁

1995 • 1,142 citations

Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas

1998 • 1,085 citations

The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts

1995 • 1,033 citations

The Mouse Locus Encodes Axin, an Inhibitor of the Wnt Signaling Pathway That Regulates Embryonic Axis Formation

1997 • 908 citations

An essential role for Rac in Ras transformation

1995 • 895 citations

The Wnt/Ca2+ pathway

2000 • 843 citations

Target genes of β-catenin–T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

1999 • 807 citations

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

1997 • 746 citations

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1988 • 745 citations

Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways

1999 • 699 citations

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

1997 • 671 citations

The oncogenic activation of β-catenin

1999 • 655 citations

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

1984 • 609 citations

A common human skin tumour is caused by activating mutations in β-catenin

1999 • 608 citations

A role for Rac in Tiaml-induced membrane ruffling and invasion

1995 • 562 citations

The role of RhoA in tissue polarity and Frizzled signalling

1997 • 558 citations

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis.

1994 • 515 citations

WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors

1998 • 499 citations

Signal transduction by the Wnt family of ligands

1998 • 474 citations

The human F box protein β-Trcp associates with the Cul1/Skp1 complex and regulates the stability of β-catenin

1999 • 432 citations

Modulation of Embryonic Intracellular Ca2+Signaling byWnt-5A

1997 • 381 citations

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

1995 • 365 citations

The Wnt/Wg Signal Transducer β-Catenin Controls Fibronectin Expression

1999 • 353 citations

Cdc42 Regulates Anchorage-Independent Growth and Is Necessary for Ras Transformation

1997 • 312 citations

WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene.

2000 • 302 citations

WISP-1 is a Wnt-1- and β-catenin-responsive oncogene

2000 • 263 citations

Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos

1987 • 261 citations

Rho family members: Activators of MAP kinase cascades

1995 • 253 citations

Identification of connexin43 as a functional target for Wnt signalling

1998 • 214 citations

5 Cellular Mechanisms of Wingless/Wnt Signal Transduction

1998 • 174 citations

The ras-Related Gene rhoB Is an Immediate-Early Gene Inducible by v-Fps, Epidermal Growth Factor, and Platelet-Derived Growth Factor in Rat Fibroblasts

1991 • 162 citations

Deregulated Expression of E2F-1 Induces S-Phase Entry and Leads to Apoptosis

1994 • 160 citations

Wnt5a cloning, expression, and up-regulation in human primary breast cancers.

1995 • 154 citations

The Mouse Wnt-1 Gene Can Act Via a Paracrine Mechanism in Transformation of Mammary Epithelial Cells

1992 • 138 citations

Evidence for the involvement of the Wnt 2 gene in human colorectal cancer.

1996 • 115 citations

The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts.

1991 • 115 citations

Growth-regulated expression of rhoG, a new member of the ras homolog gene family.

1992 • 114 citations

The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells.

1992 • 109 citations

Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line.

1992 • 109 citations

Modulation of Cell Death in Yeast by the Bcl-2 Family of Proteins

1997 • 105 citations

The C-terminal domain of Armadillo binds to hypophosphorylated Teashirt to modulate Wingless signalling in Drosophila

1999 • 74 citations

An Integral Membrane Green Fluorescent Protein Marker, Us9-GFP, Is Quantitatively Retained in Cells during Propidium Iodide-Based Cell Cycle Analysis by Flow Cytometry

1999 • 62 citations

Identification of a Mouse Homolog of the Human BTEB2 Transcription Factor as a β-Catenin-Independent Wnt-1-Responsive Gene

2001 • 61 citations

Rho Family Proteins and Regulation of the Actin Cytoskeleton

1999 • 59 citations

Activity of Wnt-1 as a transmembrane protein.

1993 • 46 citations

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

1995 • 42 citations

Growth-Regulated Expression of rhoG, a New Member of the ras Homolog Gene Family

1992 • 29 citations

Deleted Work

1955 • 0 citations