Fas and Fas Ligand Interactions Suppress Melanoma Lung Metastasis

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Apoptosis by Death Factor

1997 • 5,038 citations

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

1996 • 3,065 citations

Inhibition of death receptor signals by cellular FLIP

1997 • 2,577 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL

1995 • 1,212 citations

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture.

1990 • 1,147 citations

FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas

1995 • 702 citations

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

1996 • 574 citations

Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover.

1996 • 464 citations

Human lung carcinomas express Fas ligand.

1997 • 395 citations

Fas-mediated cytotoxicity by freshly isolated natural killer cells.

1995 • 372 citations

Expression of APO‐1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium

1994 • 310 citations

Differential requirements for antigen processing by macrophages for lysozyme-specific T cell hybridomas.

1984 • 272 citations

Anti-Fas on nonhematopoietic tumors: levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness.

1994 • 262 citations

Modulation of the Organ Microenvironment for Treatment of Cancer Metastasis

1995 • 244 citations

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages

1997 • 243 citations

Speculations on the Role of Ultraviolet Radiation in the Development of Malignant Melanoma4

1979 • 228 citations

Regulation of cell surface APO‐1/Fas (CD95) ligand expression by metalloproteases

1995 • 216 citations

Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin.

1981 • 195 citations

Enhanced Metastatic Potential of Tumor Cells Harvested From Spontaneous Metastases of Heterogeneous Murine Tumors<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref><xref ref-type="fn" rid="FN4">4</xref>

1982 • 133 citations

Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements.

1986 • 116 citations

A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice.

1996 • 104 citations

Fas/APO-1 Expression and Function on Malignant Cells of Hematologic and Nonhematologic Origin

1993 • 78 citations

Loss of Fas/Apo-1 receptor accelerates lymphomagenesis in E mu L-MYC transgenic mice but not in animals infected with MoMuLV.

1995 • 76 citations

Why do cancer cells metastasize into particular organs?

1992 • 71 citations

Lung lymphocyte elimination by apoptosis in the murine response to intratracheal particulate antigen.

1997 • 54 citations

Effect of human natural killer cells on the metastatic growth of human melanoma xenografts in mice with severe combined immunodeficiency.

1994 • 49 citations

Production of lymphotoxin (LTα) and a soluble dimeric form of its receptor using the baculovirus expression system

1994 • 45 citations

Modulation of growth and apoptosis response in PC-3 and LNCAP prostate-cancer cell lines by FAS

1996 • 36 citations

Stimulatory and inhibitory activities of lung-conditioned medium on the growth of normal and neoplastic cells in vitro.

1985 • 32 citations

Predominance of the metastatic phenotype in hybrids formed by fusion of mouse and human melanoma clones

1996 • 25 citations