Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover.

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

The Fas Death Factor

1995 • 4,070 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Mechanisms and Genes of Cellular Suicide

1995 • 2,514 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1995 • 1,662 citations

Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

1994 • 1,558 citations

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

1994 • 1,549 citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

1995 • 1,346 citations

A novel domain within the 55 kd TNF receptor signals cell death

1993 • 1,302 citations

Lpr and gld: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative Disease

1991 • 1,185 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Mechanism of antigen-driven selection in germinal centres

1989 • 1,097 citations

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1994 • 1,073 citations

T-cell apoptosis detected in situ during positive and negative selection in the thymus

1994 • 1,071 citations

Fas ligand mediates activation-induced cell death in human T lymphocytes.

1995 • 949 citations

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

1993 • 857 citations

The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen.

1992 • 839 citations

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1994 • 708 citations

Expression of the Fas ligand in cells of T cell lineage.

1995 • 659 citations

Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

1993 • 643 citations

The mouse fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

1994 • 335 citations

Unraveling Immune Privilege

1995 • 302 citations

Deletion of cells by apoptosis during castration-induced involution of the rat prostate

1973 • 285 citations

Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice.

1988 • 142 citations

Facultative polypeptide translocation allows a single mRNA to encode the secreted and cytosolic forms of plasminogen activators inhibitor 2.

1989 • 140 citations

Murine clusterin: molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis

1993 • 127 citations

The death domain motif found in Fas (Apo‐1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance

1995 • 109 citations

Characterization of uterine epithelium apoptotic cell death kinetics and regulation by progesterone and RU 486.

1992 • 109 citations

Preferential distribution of apoptotic bodies in acinar zone 3 of normal human and rat liver

1988 • 86 citations

Characterization of the non-functional Fas ligand of gld mice

1995 • 67 citations

Membrane Attack Complex (MAC) Deposits in Skin Are Not Always Accompanied by S-Protein and Clusterin

1992 • 19 citations

Development of the T cell receptor repertoire in lpr mice

1994 • 17 citations

LN-6: a monoclonal antibody to vimentin expressed in non-hematopoietic mesenchymal cells and derived tumors and reactive in B5-fixed, paraffin-embedded tissues.

1989 • 5 citations