Kindling and associated mossy fibre sprouting are not affected in mice deficient of NGFI-AINGFI-B genes

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun

1991 • 2,666 citations

Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure

1987 • 1,771 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways

1993 • 1,165 citations

Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation

1989 • 1,014 citations

Synaptic Reorganization in the Hippocampus Induced by Abnormal Functional Activity

1988 • 912 citations

Histochemical demonstration of heavy metals

1981 • 758 citations

A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences.

1988 • 733 citations

Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system.

1995 • 685 citations

Differential expression of immediate early genes in the hippocampus and spinal cord

1990 • 670 citations

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene

1988 • 661 citations

Cellular and molecular basis of epilepsy

1994 • 657 citations

Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis

1991 • 636 citations

Limbic Seizures Increase Neuronal Production of Messenger RNA for Nerve Growth Factor

1989 • 624 citations

Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells.

1988 • 580 citations

Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus

1987 • 579 citations

Identification of the DNA Binding Site for NGFI-B by Genetic Selection in Yeast

1991 • 566 citations

Luteinizing Hormone Deficiency and Female Infertility in Mice Lacking the Transcription Factor NGFI-A (Egr-1)

1996 • 479 citations

L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes

1991 • 429 citations

The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction.

1993 • 397 citations

Convulsant-induced increase in transcription factor messenger RNAs in rat brain.

1988 • 377 citations

Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models

1988 • 320 citations

Unimpaired Thymic and Peripheral T Cell Death in Mice Lacking the Nuclear Receptor NGFI-B (Nur77)

1995 • 273 citations

Seizure-Induced Changes in Neurotrophin Expression: Implications for Epilepsy

1993 • 229 citations

Induction of c-fos mRNA by kindled seizures: complex relationship with neuronal burst firing

1993 • 223 citations

EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

1991 • 218 citations

The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family.

1991 • 201 citations

Regulation of neurotrophin and traka, trkb and trkc tyrosine kinase receptor messenger RNA expression in kindling

1993 • 199 citations

The kindling model of epilepsy

1983 • 197 citations

The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene.

1990 • 190 citations

NMDA and non-NMDA receptor-mediated increase of c-fos mRNA in dentate gyrus neurons involves calcium influx via different routes

1992 • 183 citations

Epilepsy induced collateral sprouting of hippocampal mossy fibers: Does it induce the development of ectopic synapses with granule cell dendrites?

1993 • 180 citations

Anticonvulsant action of a non-competitive antagonist of NMDA receptors (MK-801) in the kindling model of epilepsy

1989 • 179 citations

Correlation between the induction of an immediate early gene,zif/268, and long-term potentiation in the dentate gyrus

1992 • 168 citations

The NGFI-B gene, a transcriptionally inducible member of the steroid receptor gene superfamily: genomic structure and expression in rat brain after seizure induction.

1989 • 167 citations

Growth and Differentiation Proceeds Normally in Cells Deficient in the Immediate Early Gene NGFI-A

1995 • 165 citations

Adrenocortical Function and Regulation of the Steroid 21-Hydroxylase Gene in NGFI-B-Deficient Mice

1995 • 146 citations

Induction of c‐fos mRNA Expression by Afterdischarge in the Hippocampus of Naive and Kindled Rats

1990 • 146 citations

The NMDA-receptor antagonist, MK-801, suppresses limbic kindling and kindled seizures

1988 • 143 citations

Null Mutation of c-fosImpairs Structural and Functional Plasticities in the Kindling Model of Epilepsy

1996 • 135 citations

NMDA Receptor Dependence of Kindling and Mossy Fiber Sprouting: Evidence that the NMDA Receptor Regulates Patterning of Hippocampal Circuits in the Adult Brain

1996 • 133 citations

Seizures increase basic fibroblast growth factor mRNA in adult rat forebrain neurons and glia

1994 • 117 citations

Differential expression of immediate early genes in the hippocampus in the kindling model of epilepsy

1991 • 105 citations

Regional expression of c-fos mRNA in rat brain during the evolution of amygdala kindled seizures

1991 • 100 citations

Basal expression of Fos, Fos-related, Jun, and Krox 24 proteins in rat hippocampus

1992 • 97 citations

Unimpaired Macrophage Differentiation and Activation in Mice Lacking the Zinc Finger Transcription Factor NGFI-A (EGR1)

1996 • 97 citations

High-frequency discharge of dentate granule cells, but not long-term potentiation, induces c-fos protein

1988 • 93 citations

Expression of the nerve growth factor-regulated NGFI-A and NGFI-B genes in the developing rat

1990 • 93 citations

High basal expression of the immediate early gene in cortical layers IV and VI, in CA1 and in the corpus striatum - an in situ hybridization study

1991 • 84 citations

Induction of F1/GAP-43 gene: expression in hippocampal granule cells after seizures

1993 • 79 citations

aFGF, bFGF and flg mRNAs Show Distinct Patterns of Induction in the Hippocampus Following Kainate‐induced Seizures

1994 • 78 citations

Increased Expression of GAP‐43, Somatostatin and Neuropeptide Y mRNA in the Hippocampus During Development of Hippocampal Kindling in Rats

1993 • 62 citations

Differences in the anatomic distribution of immediate-early gene expression in amygdala and angular bundle kindling development

1995 • 59 citations

Effects of competitive and noncompetitive NMDA receptor antagonists on kindling and LTP

1991 • 58 citations

In vivo mutational analysis of the NGFI-A zinc fingers.

1992 • 55 citations

Developmental regulation of Fos and Fos‐related antigens in cerebral cortex, striatum, hippocampus, and cerebellum of the rat

1993 • 55 citations

Localization of the NGFI-A protein in the rat brain

1990 • 55 citations

Transcriptional regulation of the adrenal steroidogenic enzymes

1993 • 53 citations

N-methyl-D-aspartate receptors activate transcription of c-fos and NGFI-A by distinct phospholipase A2-requiring intracellular signaling pathways.

1995 • 34 citations