The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

A homologous protein-coding sequence in drosophila homeotic genes and its conservation in other metazoans

1984 • 920 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

Homeo Boxes in the Study of Development

1987 • 905 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences.

1988 • 733 citations

A new class of yeast transcriptional activators

1987 • 706 citations

A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

1984 • 674 citations

Three-Dimensional Solution Structure of a Single Zinc Finger DNA-Binding Domain

1989 • 630 citations

Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells.

1988 • 580 citations

Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain

1989 • 566 citations

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

1989 • 511 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells.

1988 • 428 citations

Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines

1988 • 417 citations

The primary structure of transcription factor TFIIIA has 12 consecutive repeats

1985 • 413 citations

Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins.

1988 • 411 citations

Homeobox proteins as sequence-specific transcription factors

1988 • 397 citations

Distinct Regions of Sp1 Modulate DNA Binding and Transcriptional Activation

1988 • 389 citations

Transient expression of genes introduced into cultured cells of Drosophila.

1983 • 370 citations

The GLI-Kruppel family of human genes.

1988 • 302 citations

Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure.

1988 • 301 citations

Glucocorticoid Receptor Mutants That Define a Small Region Sufficient for Enhancer Activation

1987 • 260 citations

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

1987 • 260 citations

Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

1988 • 238 citations

Several distinct "CCAAT" box binding proteins coexist in eukaryotic cells.

1988 • 230 citations

Segment-specific expression of a homoeobox-containing gene in the mouse hindbrain

1989 • 214 citations

Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor.

1984 • 199 citations

A multigene family encoding several “finger” structures is present and differentially active in mammalian genomes

1987 • 197 citations

Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation

1989 • 192 citations

Two gene members of the murine HOX-5 complex show regional and cell-type specific expression in developing limbs and gonads.

1989 • 176 citations

A model for the tertiary structure of the 28 residue DNA-binding motif (‘zinc finger’) common to many eukaryotic transcriptional regulatory proteins

1988 • 159 citations

Structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos.

1989 • 155 citations

A new homeo-box is present in overlapping cosmid clones which define the mouse Hox-1 locus.

1986 • 134 citations

Characterization of a mouse multigene family that encodes zinc finger structures.

1988 • 127 citations

Homoeobox gene expression in mouse embryos varies with position by the primitive streak stage

1986 • 126 citations

A Mouse Homeo Box Gene Is Expressed in Spermatocytes and Embryos

1986 • 121 citations

Isolation of a mouse cDNA coding for a developmentally regulated, testis-specific transcript containing homeo box homology.

1986 • 111 citations

Differential expression of the mouse homeobox-containing gene Hox-1.4 during male germ cell differentiation and embryonic development.

1987 • 106 citations

The mouse Hox-1.4 gene: primary structure, evidence for promoter activity and expression during development

1989 • 100 citations

The GLI-Kruppel Family of Human Genes

1988 • 78 citations

The finger motif defines a multigene family represented in the maternal mRNA of Xenopus laevis oocytes.

1988 • 45 citations

The primary structure of the murine multifinger gene mKr2 and its specific expression in developing and adult neurons.

1988 • 45 citations

Characterization of a Mouse Multigene Family That Encodes Zinc Finger Structures

1988 • 41 citations

Structure, Chromosome Location, and Expression of the Mouse Zinc Finger Gene Krox-20: Multiple Gene Products and Coregulation with the Proto-Oncogene c-fos

1989 • 38 citations