NMDA Receptor Dependence of Kindling and Mossy Fiber Sprouting: Evidence that the NMDA Receptor Regulates Patterning of Hippocampal Circuits in the Adult Brain

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun

1991 • 2,666 citations

Mossy fiber synaptic reorganization in the epileptic human temporal lobe

1989 • 1,150 citations

Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats

1985 • 1,101 citations

Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy

1989 • 917 citations

Synaptic Reorganization in the Hippocampus Induced by Abnormal Functional Activity

1988 • 912 citations

Impulse activity and the patterning of connections during cns development

1990 • 770 citations

Cellular and molecular basis of epilepsy

1994 • 657 citations

Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis

1991 • 636 citations

Limbic Seizures Increase Neuronal Production of Messenger RNA for Nerve Growth Factor

1989 • 624 citations

Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy

1990 • 615 citations

Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus

1987 • 579 citations

Neurotrophins and brain insults

1994 • 564 citations

Mossy fiber synaptic reorganization induced by kindling: time course of development, progression, and permanence

1991 • 539 citations

A light and electron microscopic analysis of the mossy fibers of the rat dentate gyrus

1986 • 489 citations

Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures

1994 • 461 citations

Zinc-Induced Collapse of Augmented Inhibition by GABA in a Temporal Lobe Epilepsy Model

1996 • 419 citations

Progressive neuronal loss induced by kindling: a possible mechanism for mossy fiber synaptic reorganization and hippocampal sclerosis

1990 • 408 citations

NMDA receptors of dentate gyrus granule cells participate in synaptic transmission following kindling

1987 • 401 citations

Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats

1992 • 369 citations

Electrographic Seizures and New Recurrent Excitatory Circuits in the Dentate Gyrus of Hippocampal Slices from Kainate-Treated Epileptic Rats

1996 • 361 citations

Noncompetitive excitatory amino acid receptor antagonists

1990 • 361 citations

Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models

1988 • 320 citations

Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers

1992 • 279 citations

Activation of N-methyl-D-aspartate receptors parallels changes in cellular and synaptic properties of dentate gyrus granule cells after kindling

1988 • 261 citations

Seizure-Induced Changes in Neurotrophin Expression: Implications for Epilepsy

1993 • 229 citations

Induction of c-fos mRNA by kindled seizures: complex relationship with neuronal burst firing

1993 • 223 citations

Regulation of neurotrophin and traka, trkb and trkc tyrosine kinase receptor messenger RNA expression in kindling

1993 • 199 citations

NMDA receptor agonist and antagonists alter retinal ganglion cell arbor structure in the developing frog retinotectal projection

1990 • 196 citations

Hippocampal plasticity in the kindling model of epilepsy in rats

1989 • 196 citations

NMDA and non-NMDA receptor-mediated increase of c-fos mRNA in dentate gyrus neurons involves calcium influx via different routes

1992 • 183 citations

Hippocampal plasticity in childhood epilepsy

1989 • 180 citations

Anticonvulsant action of a non-competitive antagonist of NMDA receptors (MK-801) in the kindling model of epilepsy

1989 • 179 citations

The dithizone, Timm's sulphide silver and the selenium methods demonstrate a chelatable pool of zinc in CNS

1985 • 171 citations

Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics

1994 • 169 citations

Anticonvulsant and behavioral effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine.

1991 • 161 citations

Induction of c‐fos mRNA Expression by Afterdischarge in the Hippocampus of Naive and Kindled Rats

1990 • 146 citations

Mesial temporal sclerosis : historical background and an overview from a modern perspective

1997 • 144 citations

Developmental analysis of hippocampal mossy fiber outgrowth in a mutant mouse with inherited spike-wave seizures

1993 • 137 citations

Null Mutation of c-fosImpairs Structural and Functional Plasticities in the Kindling Model of Epilepsy

1996 • 135 citations

The NMDA antagonist, MK-801, suppresses long-term potentiation, kindling, and kindling-induced potentiation in the perforant path of the unanesthetized rat

1990 • 132 citations

Quantitative analysis of synaptic potentiation during kindling of the perforant path

1986 • 115 citations

Alteration of long-lasting structural and functional effects of kainic acid in the hippocampus by brief treatment with phenobarbital

1992 • 109 citations

Activation of the dentate gyrus by pentylenetetrazol evoked seizures induces mossy fiber synaptic reorganization

1992 • 103 citations

The effect of the non-NMDA receptor antagonists GYKI 52466 and NBQX and the competitive NMDA receptor antagonist d-CPPene on the development of amygdala kindling and on amygdala-kindled seizures

1994 • 103 citations

Chronic epileptogenesis induced by kindling of the entorhinal cortex: the role of the dentate gyrus

1986 • 100 citations

Deficits in radial arm maze performance in kindled rats: evidence for long-lasting memory dysfunction induced by repeated brief seizures

1995 • 90 citations

Pharmacological modification of amygdaloid-kindled seizures

1980 • 81 citations

A reevaluation of excitatory amino acid-mediated synaptic transmission in rat dentate gyrus

1990 • 80 citations

Induction of F1/GAP-43 gene: expression in hippocampal granule cells after seizures

1993 • 79 citations

aFGF, bFGF and flg mRNAs Show Distinct Patterns of Induction in the Hippocampus Following Kainate‐induced Seizures

1994 • 78 citations

Septotemporal variation of the supragranular projection of the mossy fiber pathway in the dentate gyrus of normal and kindled rats

1992 • 73 citations

The Imaging of Individual Atoms

1996 • 72 citations

Excessive intra- and supragranular mossy fibers in the dentate gyrus of tottering (tg/tg) mice

1989 • 69 citations

MK-801 prevents chemical kindling induced by pentylenetetrazol in rats

1991 • 69 citations

Evidence implicating dentate granule cells in development of entorhinal kindling

1986 • 68 citations

Increased Expression of GAP‐43, Somatostatin and Neuropeptide Y mRNA in the Hippocampus During Development of Hippocampal Kindling in Rats

1993 • 62 citations

Functional alterations in the dentate gyrus after induction of long-term potentiation, kindling, and mossy fiber sprouting

1996 • 62 citations

Differences in the anatomic distribution of immediate-early gene expression in amygdala and angular bundle kindling development

1995 • 59 citations

Molecular correlates between reactive and developmental plasticity in the rat hippocampus

1995 • 43 citations

Potentiation of inhibition with perforant path kindling: an NMDA-receptor dependent process

1991 • 39 citations

Ketamine-induced changes in kindled amygdaloid seizures

1983 • 30 citations