Differential expression of immediate early genes in the hippocampus in the kindling model of epilepsy

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure

1987 • 1,771 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

Transcriptional autoregulation of the proto-oncogene fos

1988 • 630 citations

Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro.

1987 • 630 citations

Limbic Seizures Increase Neuronal Production of Messenger RNA for Nerve Growth Factor

1989 • 624 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus

1987 • 579 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

Regulation of Proenkephalin by Fos and Jun

1989 • 546 citations

Viral and cellular fos proteins: A comparative analysis

1984 • 523 citations

fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.

1988 • 518 citations

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.

1988 • 511 citations

Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction.

1989 • 502 citations

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

1988 • 455 citations

Dynamic alterations occur in the levels and composition of transcription factor AP-1 complexes after seizure

1989 • 355 citations

Transcriptional regulation by dimerization: Two sides to an incestuous relationship

1990 • 343 citations

Glutamate receptor agonists increase the expression of Fos, Fra, and AP‐1 DNA binding activity in the mammalian brain

1989 • 330 citations

Helix-turn-helix, zinc-finger, and leucine-zipper motifs for eukaryotic transcriptional regulatory proteins

1989 • 306 citations

Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding

1989 • 281 citations

In primary cultures of cerebellar granule cells the activation of N-methyl-D-aspartate-sensitive glutamate receptors induces c-fos mRNA expression.

1989 • 236 citations

Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1

1990 • 221 citations

Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements.

1990 • 218 citations

The kindling model of epilepsy: a critical review.

1985 • 186 citations

Induction of c‐fos mRNA Expression by Afterdischarge in the Hippocampus of Naive and Kindled Rats

1990 • 146 citations

Electrode placement and kindling-induced experiemental epilepsy

1978 • 141 citations

Excitatory Amino Acids and Neuronal Plasticity

1990 • 121 citations

Relationships between seizure activity and cyclic nucleotide levels in brain

1980 • 102 citations

Proto-oncogenes in the nervous system

1988 • 98 citations

Pursuit of the mechanisms of kindling

1988 • 93 citations

Changing Fos oncoprotein to a Jun-independent DNA-binding protein with GCN4 dimerization specificity by swapping "leucine zippers"

1989 • 90 citations

Characterization of rat c-mycand adjacent regions

1987 • 90 citations

Amygdala kindling and c-fos protein(s)☆

1988 • 81 citations

MK-801, an antagonist of NMDA receptors, inhibits injury-induced c-fos protein accumulation in rat brain

1990 • 77 citations

Structure and expression of B-myc, a new member of the myc gene family.

1988 • 63 citations

Effect of inhibitors of protein synthesis on the development of kindled seizures in rats

1979 • 51 citations

Microiontophoresis of flurazepam on inspiratory and postinspiratory neurons in the ventrolateral medulla of cats: An intracellular study in vivo

1989 • 14 citations

Kindling, Prenatal Exposure to Ethanol and Postnatal Development Selectively Alter Reponses of Hippocampal Pyramidal Cells to NMDA

1990 • 5 citations