Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

1995 • 1,528 citations

The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions.

1998 • 1,382 citations

Breeding of a Non-Obese, Diabetic Strain of Mice

1980 • 1,255 citations

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes.

1996 • 1,196 citations

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 • 1,187 citations

Untitled

1996 • 780 citations

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response

1991 • 766 citations

Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry

1998 • 669 citations

Coordinate Regulation of Complex T Cell Populations Responding to Bacterial Infection

1998 • 535 citations

The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance — a review

1985 • 523 citations

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes.

1994 • 452 citations

Virus-induced diabetes mellitus

1977 • 433 citations

Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes.

2000 • 375 citations

Genetic heterogeneity, modes of inheritance, and risk estimates for a joint study of Caucasians with insulin-dependent diabetes mellitus.

1988 • 371 citations

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

1994 • 309 citations

Attrition of T Cell Memory

1999 • 278 citations

T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens

2002 • 259 citations

Die and Let Live: Eliminating Dangerous Lymphocytes

1996 • 242 citations

Genomic and Biological Variation among Commonly Used Lymphocytic Choriomeningitis Virus Strains

1983 • 241 citations

Interferon-γ Is Essential for Destruction of β Cells and Development of Insulin-dependent Diabetes Mellitus

1997 • 220 citations

Perspectives in virology

1961 • 212 citations

Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient mice.

1996 • 203 citations

Prevention of Type I Diabetes in Nonobese Diabetic Mice by Virus Infection

1988 • 202 citations

IL-1β and IFN-γ induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice

2003 • 192 citations

Intrathecal Delivery of IFN-γ Protects C57BL/6 Mice from Chronic-Progressive Experimental Autoimmune Encephalomyelitis by Increasing Apoptosis of Central Nervous System-Infiltrating Lymphocytes

2001 • 188 citations

Autoreactive CD4+ T Cells Protect from Autoimmune Diabetes via Bystander Suppression Using the IL-4/Stat6 Pathway

1999 • 184 citations

Among CXCR3 Chemokines, IFN-γ-Inducible Protein of 10 kDa (CXC Chemokine Ligand (CXCL) 10) but Not Monokine Induced by IFN-γ (CXCL9) Imprints a Pattern for the Subsequent Development of Autoimmune Disease

2003 • 180 citations

Induction of Type I Diabetes by Kilham's Rat Virus in Diabetes-Resistant BB/Wor Rats

1991 • 180 citations

Coexpression of B7-1 and viral (“self”) transgenes in pancreatic β cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes

1995 • 177 citations

Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: prospective twin study

1999 • 177 citations

Identification of Db- and Kb-Restricted Subdominant Cytotoxic T-Cell Responses in Lymphocytic Choriomeningitis Virus-Infected Mice

1998 • 164 citations

Comparison of Activation versus Induction of Unresponsiveness of Virus-Specific CD4+ and CD8+ T Cells upon Acute versus Persistent Viral Infection

1998 • 159 citations

Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2.

1996 • 153 citations

A Dual Role for TNF-α in Type 1 Diabetes: Islet-Specific Expression Abrogates the Ongoing Autoimmune Process When Induced Late but Not Early During Pathogenesis

2001 • 152 citations

Optimal lymphocytic choriomeningitis virus sequences restricted by H-2Db major histocompatibility complex class I molecules and presented to cytotoxic T lymphocytes

1995 • 121 citations

Molecular characterization of the genomic S RNA segment from lymphocytic choriomeningitis virus

1987 • 108 citations

Virus Persists in β Cells of Islets of Langerhans and Is Associated with Chemical Manifestations of Diabetes

1984 • 107 citations

Viruses as therapeutic agents. I. Treatment of nonobese insulin-dependent diabetes mice with virus prevents insulin-dependent diabetes mellitus while maintaining general immune competence.

1990 • 89 citations

Perspectives in Virology

1982 • 86 citations

CTL Escape Viral Variants

1995 • 83 citations

Role of viruses in type I diabetes

1998 • 60 citations

Cytokine secretion patterns in twins discordant for Type I diabetes

1999 • 52 citations

Virus-Induced Diabetes in a Transgenic Model: Role of Cross-Reacting Viruses and Quantitation of Effector T Cells Needed To Cause Disease

2000 • 51 citations

Abrogation of diabetes in BB rats by acute virus infection. Association of viral-lymphocyte interactions.

1988 • 36 citations

Viruses as a triggering factor of type 1 diabetes and genetic markers related to the susceptibility to the virus-associated diabetes

1989 • 34 citations

Viruses as therapeutic agents

1999 • 29 citations

Persistent Viral Infection of the Thyroid Gland: Alteration of Thyroid Function in the Absence of Tissue Injury*

1988 • 26 citations

Obstacles to identifying viruses that cause autoimmune disease

2000 • 24 citations

Virus persists in beta cells of islets of Langerhans and infection is associated with chemical manifestations of diabetes. II. Morphologic observations.

1985 • 20 citations

Persistent virus infection associated with chemical manifestations of diabetes. II. Role of viral strain, environmental insult, and host genetics.

1987 • 18 citations