Coordinate Regulation of Complex T Cell Populations Responding to Bacterial Infection

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by Listeria -Induced Macrophages

1993 • 3,140 citations

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

Immunological Memory and Protective Immunity: Understanding Their Relation

1996 • 1,771 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells.

1996 • 917 citations

The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.

1994 • 838 citations

Dominance and Crypticity of T Cell Antigenic Determinants

1993 • 838 citations

CTLA-4 ligation blocks CD28-dependent T cell activation.

1996 • 787 citations

Use of Peptide Libraries to Map the Substrate Specificity of a Peptide-Modifying Enzyme: A 13 Residue Consensus Peptide Specifies Biotinylation in Escherichia coli

1993 • 586 citations

Antigen-Specific Development of Primary and Memory T Cells in Vivo

1995 • 444 citations

Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes

1991 • 425 citations

Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability.

1996 • 389 citations

Immediate Early and Early Lytic Cycle Proteins Are Frequent Targets of the Epstein-Barr Virus–induced Cytotoxic T Cell Response

1997 • 362 citations

Roles of alphabeta and gammadelta T Cell Subsets in Viral Immunity

1992 • 350 citations

Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.

1995 • 323 citations

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire.

1991 • 323 citations

Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells.

1997 • 263 citations

CD8+ T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo.

1992 • 260 citations

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

1996 • 259 citations

Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules

1995 • 225 citations

Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance

1997 • 214 citations

MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL.

1997 • 207 citations

Use of adoptive transfer of T‐cell antigen‐receptor‐transgenic T cells for the study of T‐cell activation in vivo

1997 • 205 citations

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen.

1992 • 204 citations

Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection.

1996 • 189 citations

Single-Cell PCR Analysis of TCR Repertoires Selected by Antigen In Vivo: A High Magnitude CD8 Response Is Comprised of Very Few Clones

1996 • 174 citations

Epitope focusing in the primary cytotoxic T cell response to Epstein-Barr virus and its relationship to T cell memory.

1996 • 171 citations

Processing and delivery of peptides presented by MHC class I molecules

1996 • 161 citations

Direct sequence identification and kinetic analysis of an MHC class I-restricted Listeria monocytogenes CTL epitope.

1994 • 161 citations

Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2.

1996 • 153 citations

Immunity to intracellular microbial pathogens

1995 • 152 citations

MHC Class I/Peptide Stability: Implications for Immunodominance, In Vitro Proliferation, and Diversity of Responding CTL

1998 • 149 citations

Immunodominant and subdominant CTL responses to Listeria monocytogenes infection.

1997 • 146 citations

The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4.

1996 • 132 citations

Immunodominance analysis of CTL responses to influenza PR8 virus reveals two new dominant and subdominant Kb-restricted epitopes.

1996 • 128 citations

Immunological memory

1997 • 124 citations

Efficiency of MHC class I antigen processing: A quantitative analysis

1994 • 121 citations

MHC class I antigen processing of Listeria monocytogenes proteins: implications for dominant and subdominant CTL responses

1997 • 112 citations

Listeriolysin is processed efficiently into an MHC class I-associated epitope in Listeria monocytogenes-infected cells.

1995 • 109 citations

Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies.

1996 • 99 citations

The MHC class l-restricted T cell response to Sendai virus infection in C57BL/6 mice: a single immunodominant epitope elicits an extremely diverse repertoire of T cells

1994 • 95 citations

Quantitative Contribution of CD4 and CD8 to T Cell Antigen Receptor Serial Triggering

1997 • 94 citations

Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein.

1997 • 93 citations

Enhanced Intracellular Dissociation of Major Histocompatibility Complex Class I–associated Peptides: A Mechanism for Optimizing the Spectrum of Cell Surface–Presented Cytotoxic T Lymphocyte Epitopes

1997 • 89 citations

Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential V beta bias

1995 • 87 citations

Identification of a major I-Ek-restricted determinant of hen egg lysozyme: limitations of lymph node proliferation studies in defining immunodominance and crypticity.

1995 • 69 citations

Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response.

1995 • 67 citations

Immunodominance is independent of structural constraints: each region within hen eggwhite lysozyme is potentially available upon processing of native antigen.

1997 • 51 citations

Enumeration of single IFN-gamma-producing cells in mice during viral and bacterial infection.

1989 • 50 citations

A nonamer peptide derived from Listeria monocytogenes metalloprotease is presented to cytolytic T lymphocytes

1997 • 45 citations

The weak CD8+ CTL response to an influenza hemagglutinin epitope reflects limited T cell availability.

1996 • 40 citations

Restriction of self‐antigen presentation to cytolytic T lymphocytes by mouse peptide pumps

1995 • 12 citations