Tumors with reduced expression of a cytotoxic T lymphocyte recognized antigen lack immunogenicity but retain sensitivity to lysis by cytotoxic T lymphocytes

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

1991 • 3,493 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

1980 • 835 citations

Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells.

1987 • 735 citations

Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity.

1990 • 414 citations

Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesis.

1977 • 400 citations

Reversal of Oncogenesis by the Expression of a Major Histocompatibility Complex Class I Gene

1985 • 375 citations

Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.

1988 • 330 citations

Exogenous expression of mouse interferon gamma cDNA in mouse neuroblastoma C1300 cells results in reduced tumorigenicity by augmented anti-tumor immunity.

1989 • 284 citations

Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression.

1983 • 251 citations

A nonimmunogenic sarcoma transduced with the cDNA for interferon gamma elicits CD8+ T cells against the wild-type tumor: correlation with antigen presentation capability.

1992 • 159 citations

Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity.

1988 • 118 citations

Variation of Antigenic Characteristics Between Different Mouse Lymphomas Induced by the Moloney Virus2

1966 • 116 citations

Fundamental immunology

1990 • 112 citations

Multiple tumour-specific antigens expressed on a single tumour cell

1983 • 107 citations

Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells.

1989 • 101 citations

Differentiation-dependent sensitivity of human B-cell-derived lines to major histocompatibility complex-restricted T-cell cytotoxicity.

1986 • 96 citations

Characterization of a progressive tumor from C3H fibroblasts transformed in vitro with SV40 virus. Immunoresistance in vivo correlates with phenotypic loss of H-2Kk.

1982 • 95 citations

Major histocompatibility complex class I and unique antigen expression by murine tumors that escaped from CD8+ T-cell-dependent surveillance.

1990 • 91 citations

The murine MHC class I genes, H-2Dq and H-2Lq, are strikingly homologous to each other, H-2Ld, and two genes reported to encode tumor-specific antigens.

1988 • 67 citations

Identification of a unique tumor-specific antigen as a novel class I major histocompatibility molecule.

1985 • 67 citations

CD4+ AND B LYMPHOCYTES IN TRANSPLANTATION IMMUNITY

1993 • 65 citations

Mechanisms of anti-tumor action of Corynebacterium parvum. I. Potentiated tumor-specific immunity and its therapeutic limitations.

1981 • 60 citations

Immunoselection of tumor cell variants by mice suppressed with ultraviolet radiation.

1982 • 49 citations

Cytotoxic T lymphocytes (CTL) against a transforming gene product select for transformed cells with point mutations within sequences encoding CTL recognition epitopes.

1992 • 44 citations

Identification of a unique tumor antigen as rejection antigen by molecular cloning and gene transfer.

1986 • 44 citations

Allogeneic H-2 antigen expression is insufficient for tumor rejection.

1987 • 40 citations

Independent immunodominant and immunorecessive tumor-specific antigens on a malignant tumor: antigenic dissection with cytolytic T cell clones.

1983 • 38 citations

Highly malignant tumor variants retain tumor-specific antigens recognized by T helper cells.

1986 • 36 citations

Reduced tumorigenicity of a spontaneous mouse lung carcinoma following H-2 gene transfection.

1987 • 33 citations

ISOLATION OF THE MHC GENES ENCODING THE TUMOUR‐SPECIFIC CLASS I ANTIGENS EXPRESSED ON A MURINE FIBROSARCOMA

1986 • 29 citations

Primary virus-induced lymphomas evade T cell immunity by failure to express viral antigens.

1989 • 22 citations

Molecular characterization of novel H-2 class I molecules expressed by a C3H UV-induced fibrosarcoma.

1985 • 22 citations

CD4-POSITIVE AND B LYMPHOCYTES IN TRANSPLANTATION IMMUNITY

1993 • 22 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg) X. Tumorigenic potential of mouse cells transformed by SV40 in high responder C57BL/6 mice and correlation with the persistence of SV40 TrAg, early proteins and viral sequences

1983 • 21 citations

Immunologic selection of simian virus 40 (SV40) T-antigen-negative tumor cells which arise by excision of early SV40 DNA

1986 • 9 citations