Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops

Capturing Chromosome Conformation

2002 • 3,550 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Genomic imprinting: parental influence on the genome

2001 • 2,253 citations

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

2000 • 1,706 citations

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

2000 • 1,493 citations

Looping and Interaction between Hypersensitive Sites in the Active β-globin Locus

2002 • 1,322 citations

Controlling the double helix

2003 • 1,102 citations

Long-range chromatin regulatory interactions in vivo

2002 • 651 citations

Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

1998 • 641 citations

CTCF Tethers an Insulator to Subnuclear Sites, Suggesting Shared Insulator Mechanisms across Species

2004 • 478 citations

Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

2000 • 439 citations

Imprinting and the Epigenetic Asymmetry Between Parental Genomes

2001 • 411 citations

An enhancer deletion affects both H19 and Igf2 expression.

1995 • 398 citations

Genomic Imprinting: Intricacies of Epigenetic Regulation in Clusters

2003 • 278 citations

Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes

1994 • 277 citations

Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function

2000 • 255 citations

Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2

1997 • 248 citations

Setting the Boundaries of Chromatin Domains and Nuclear Organization

2002 • 215 citations

Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes

2002 • 214 citations

Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19

2000 • 203 citations

Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions

2003 • 188 citations

An intragenic methylated region in the imprinted Igf2 gene augments transcription

2001 • 151 citations

Considering Nuclear Compartmentalization in the Light of Nuclear Dynamics

2003 • 130 citations

Mechanisms of Igf2/H19 Imprinting: DNA Methylation, Chromatin and Long-Distance Gene Regulation

2000 • 124 citations

Regulatory Mechanisms at the MouseIgf2/H19 Locus

2001 • 107 citations

An upstream repressor element plays a role in Igf2 imprinting

2001 • 99 citations

5 The origins of genomic imprinting in mammals

2002 • 93 citations

Genomic Imprinting Controls Matrix Attachment Regionsin the Igf2Gene

2003 • 43 citations

Disruption of mesodermal enhancers forIgf2in the minute mutant

2002 • 42 citations

Igf2/H19 Imprinting Control Region (ICR): An Insulator or a Position-Dependent Silencer?

2001 • 12 citations