Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes

Translating the Histone Code

2001 • 9,488 citations

The language of covalent histone modifications

2000 • 8,260 citations

DNA methylation patterns and epigenetic memory

2002 • 6,778 citations

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1998 • 3,363 citations

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

2001 • 2,746 citations

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1998 • 2,686 citations

Genomic imprinting: parental influence on the genome

2001 • 2,253 citations

Methylation-Induced Repression— Belts, Braces, and Chromatin

1999 • 1,823 citations

Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly

2001 • 1,685 citations

Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability

2001 • 1,672 citations

Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins

1998 • 1,317 citations

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

2002 • 1,176 citations

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

1999 • 1,068 citations

The non-coding Air RNA is required for silencing autosomal imprinted genes

2002 • 1,040 citations

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

2001 • 997 citations

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

2000 • 960 citations

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

1999 • 898 citations

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

1999 • 806 citations

Transitions in Distinct Histone H3 Methylation Patterns at the Heterochromatin Domain Boundaries

2001 • 746 citations

Methylation of histone H3 Lys 4 in coding regions of active genes

2002 • 742 citations

Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component

2002 • 639 citations

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal

1993 • 602 citations

Correlation Between Histone Lysine Methylation and Developmental Changes at the Chicken β-Globin Locus

2001 • 582 citations

Imprinted expression of the Igf2r gene depends on an intronic CpG island

1997 • 578 citations

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

2002 • 555 citations

Histone Methylation

2002 • 525 citations

Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development

2001 • 510 citations

Methylation of Histone H3 at Lys-9 Is an Early Mark on the X Chromosome during X Inactivation

2001 • 504 citations

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin

2001 • 495 citations

Imprinting in Prader–Willi and Angelman syndromes

1998 • 451 citations

Dependence of Heterochromatic Histone H3 Methylation Patterns on the Arabidopsis Gene DDM1

2002 • 434 citations

Methyl‐CpG‐binding proteins

2001 • 405 citations

Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes

2001 • 369 citations

PIE-1 is a bifunctional protein that regulates maternal and zygotic gene expression in the embryonic germ line of Caenorhabditis elegans

2001 • 360 citations

Imprinting and the Initiation of Gene Silencing in the Germ Line

1998 • 359 citations

Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals

2002 • 263 citations

Active Repression of Methylated Genes by the Chromosomal Protein MBD1

2000 • 254 citations

Histone H3 Lysine 4 Methylation Disrupts Binding of Nucleosome Remodeling and Deacetylase (NuRD) Repressor Complex

2002 • 247 citations

Histone methylation defines epigenetic asymmetry in the mouse zygote.

2002 • 198 citations

Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern

1997 • 195 citations

The mCpG-binding Domain of Human MBD3 Does Not Bind to mCpG but Interacts with NuRD/Mi2 Components HDAC1 and MTA2

2002 • 174 citations

De novo deletions of SNRPN exon 1 in early human and mouse embryos result in a paternal to maternal imprint switch

2000 • 149 citations

Genomic imprinting in mammals: an interplay between chromatin and DNA methylation?

1999 • 147 citations

DNA Methylation Is Linked to Deacetylation of Histone H3, but Not H4, on the Imprinted Genes Snrpnand U2af1-rs1

2001 • 135 citations

The imprinting box of the Prader-Willi/Angelman syndrome domain

2000 • 119 citations

Parent-Specific Complementary Patterns of Histone H3 Lysine 9 and H3 Lysine 4 Methylation at the Prader-Willi Syndrome Imprinting Center

2001 • 101 citations

Methylation-Mediated Proviral Silencing Is Associated with MeCP2 Recruitment and Localized Histone H3 Deacetylation

2001 • 99 citations

Methylation-dependent silencing at the H19 imprinting control region by MeCP2

2002 • 94 citations

Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2‐H19 domain

2001 • 90 citations

Allele-Specific Histone Acetylation Accompanies Genomic Imprinting of the Insulin-Like Growth Factor II Receptor Gene**Supported by NIH Grant DK-36054 and by the Research Service of the Department of Veterans Affairs.

2000 • 60 citations

Parental Chromosome-specific Chromatin Conformation in the Imprinted U2af1-rs1 Gene in the Mouse

1997 • 48 citations

Lack of Reciprocal Genomic Imprinting of Sense and Antisense RNA of Mouse Insulin-like Growth Factor II Receptor in the Central Nervous System1

1999 • 47 citations

Inhibition of Histone Deacetylases Alters Allelic Chromatin Conformation at the Imprinted U2af1-rs1 Locus in Mouse Embryonic Stem Cells

2002 • 39 citations

An Oocyte-Specific Methylation Imprint Center in the MouseU2afbp-rs/U2af1-rs1Gene Marks the Establishment of Allele-Specific Methylation during Preimplantation Development

1997 • 24 citations

On the Uncertainty of Conclusions

1892 • 11 citations