IFN-γ fails to antagonize fibrotic effect of TGF-β on keloid-derived dermal fibroblasts

Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1993 • 2,169 citations

Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity

2001 • 1,207 citations

Fibroblasts, myofibroblasts, and wound contraction

1994 • 1,150 citations

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1997 • 1,023 citations

Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway

1999 • 800 citations

Transforming Growth Factor-β Signaling Through the Smad Pathway: Role in Extracellular Matrix Gene Expression and Regulation

2002 • 622 citations

Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing.

1988 • 559 citations

Interferon gamma decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis

1996 • 289 citations

The Effect of TGF-β on Keloid Fibroblast Proliferation and Collagen Synthesis

1996 • 289 citations

Activation of Collagen Gene Expression in Keloids: Co-Localization of Type I and VI Collagen and Transforming Growth Factor-β1 mRNA

1991 • 250 citations

Keloids: A review

1981 • 237 citations

Antagonistic Regulation of Type I Collagen Gene Expression by Interferon-γ and Transforming Growth Factor-β

2001 • 226 citations

α-Smooth muscle actin is expressed in a subpopulation of cultured and cloned fibroblasts and is modulated by γ-interferon

1992 • 209 citations

Differential Expression of Transforming Growth Factor-β Receptors I and II and Activation of Smad 3 in Keloid Fibroblasts

2001 • 187 citations

A Controlled Trial of Intralesional Recombinant Interferon-? in the Treatment of Keloidal Scarring

1990 • 165 citations

Interferon-γ inhibits experimental renal fibrosis

1999 • 144 citations

The Relationship Between Allergen-Induced Tissue Eosinophilia and Markers of Repair and Remodeling in Human Atopic Skin

2002 • 142 citations

Keloid Fibroblasts Exhibit an Altered Response to TGF-β

1992 • 132 citations

Interferon‐γ reverses the stimulation of collagen but not fibronectin gene expression by transforming growth factor‐ β in normal human fibroblasts

1990 • 89 citations

Tamoxifen Downregulates TGF-β Production in Keloid Fibroblasts

1998 • 87 citations

Effect of Tamoxifen on Transforming Growth Factor β₁Production by Keloid and Fetal Fibroblasts

2001 • 79 citations

Effects of Various Growth Factors and Histamine on Cultured Keloid Fibroblasts

1995 • 76 citations

Interferon‐γ reverses the stimulation of collagen but not fibronectin gene expression by transforming growth factor‐β in normal human fibroblasts

1990 • 71 citations

Inhibition of fibroblast chemotaxis by recombinant human interferon γ and interferon α

1987 • 62 citations

Combination of insulin-like growth factor (IGF)-I and IGF-binding protein-1 promotes fibroblast-embedded collagen gel contraction.

1996 • 56 citations

Interferon‐γ inhibits the myofibroblastic phenotype of rat palatal fibroblasts induced by transforming growth factor‐β1 in vitro

1999 • 52 citations

Sphingosylphosphorylcholine stimulates contraction of fibroblast-embedded collagen gel

2000 • 18 citations