Differential Expression of Transforming Growth Factor-β Receptors I and II and Activation of Smad 3 in Keloid Fibroblasts

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

1992 • 2,969 citations

The Discoidin Domain Receptor Tyrosine Kinases Are Activated by Collagen

1997 • 956 citations

TGFβ Signaling: Receptors, Transducers, and Mad Proteins

1996 • 840 citations

Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis.

1991 • 794 citations

Transforming Growth Factors β1 and α in Chronic Liver Disease

1991 • 655 citations

Morphological and immunochemical differences between keloid and hypertrophic scar.

1994 • 522 citations

The molecular basis of keloid and hypertrophic scar formation

1998 • 425 citations

Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3

1999 • 388 citations

TGF-β in kidney fibrosis: A target for gene therapy

1997 • 382 citations

The Effect of TGF-β on Keloid Fibroblast Proliferation and Collagen Synthesis

1996 • 289 citations

Biochemical Composition of the Connective Tissue in Keloids and Analysis of Collagen Metabolism in Keloid Fibroblast Cultures

1985 • 263 citations

Increased Expression of TGF-β Receptors by Scleroderma Fibroblasts: Evidence for Contribution of Autocrine TGF-β Signaling to Scleroderma Phenotype

1998 • 257 citations

Expression of Transforming Growth Factor Beta 1, 2, and 3 Proteins in Keloids

1999 • 233 citations

Growth kinetics and collagen synthesis of normal skin, normal scar and keloid fibroblasts in vitro

1979 • 203 citations

Modulation of Collagen Synthesis by Transforming Growth Factor-β in Keloid and Hypertrophic Scar Fibroblasts

1994 • 189 citations

Transcription and Expression of Transforming Growth Factor Type Beta in the Skin of Progressive Systemic Sclerosis: A Mediator of Fibrosis?

1990 • 177 citations

Fibronectin is overproduced by keloid fibroblasts during abnormal wound healing.

1989 • 156 citations

Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar.

1998 • 152 citations

Increased Types I and III Collagen and Transforming Growth Factor-β1 mRNA and Protein in Hypertrophic Burn Scar

1995 • 152 citations

TGF‐β receptors

1992 • 133 citations

TGF-β3 Stimulates and Regulates Collagen Synthesis Through TGF-β1-Dependent and Independent Mechanisms

1997 • 106 citations

Transforming Growth Factor β in Diabetic Nephropathy

1996 • 103 citations

Fibronectin (FN) in hypertrophic scars and keloids

1983 • 98 citations

Elevated Levels of Plasminogen Activator Inhibitor-1 May Account for the Altered Fibrinolysis by Keloid Fibroblasts

1996 • 91 citations

Retinoid Modulation of Connective Tissue Metabolism in Keloid Fibroblast Cultures

1985 • 91 citations

Gelatinase activity in keloids and hypertrophic scars

1999 • 91 citations

Transforming Growth Factor β in Diabetic Nephropathy

1996 • 85 citations

Overexpression of Insulin-Like Growth Factor-1 (IGF-I) Receptor and the Invasiveness of Cultured Keloid Fibroblasts

1999 • 79 citations

TGF-β2Activates Proliferative Scar Fibroblasts

1999 • 78 citations

Phenotypic Differences in Cytokine Responsiveness of Hypertrophic Scar Versus Normal Dermal Fibroblasts

1993 • 72 citations

Anin VivoModel of Human Proliferative Scar

1998 • 68 citations

Increased expression of tenascin C by keloids in vivo and in vitro

1999 • 61 citations

Hyaluronic acid metabolism in keloid fibroblasts

1995 • 55 citations

Quantitative assay of types I and III collagen synthesized by keloid biopsies and fibroblasts

1979 • 46 citations

Transforming growth factor-beta in glomerular injury.

1994 • 33 citations

Immunoseparation and Immunodetection of Nucleic Acids Labeled with Halogenated Nucleotides

1997 • 22 citations

Retinoid modulation of connective tissue metabolism in keloid fibroblast cultures

1985 • 14 citations