A Controlled Trial of Intralesional Recombinant Interferon-? in the Treatment of Keloidal Scarring

Interleukin 1, a potential regulator of fibroblast proliferation.

1982 • 835 citations

Selective inhibition of human diploid fibroblast collagen synthesis by interferons.

1984 • 336 citations

THE SURGICAL TREATMENT OF KELOIDS

1961 • 286 citations

Gamma interferon is the lymphokine and beta interferon the monokine responsible for inhibition of fibroblast collagen production and late but not early fibroblast proliferation.

1985 • 278 citations

Silicone gel: a new treatment for burn scars and contractures

1983 • 267 citations

Biologic Basis for the Treatment of Keloids and Hypertrophic Scars

1970 • 240 citations

Keloids: A review

1981 • 237 citations

Detection of a gamma interferon-induced protein IP-10 in psoriatic plaques.

1988 • 231 citations

Non-pressure treatment of hypertrophic scars

1985 • 189 citations

Role of interferon-gamma in cutaneous trafficking of lymphocytes with emphasis on molecular and cellular adhesion events.

1988 • 189 citations

Gamma-interferon inhibits collagen synthesis in vivo in the mouse.

1987 • 181 citations

Short-term keloid treatment in vivo with human interferon alfa-2b results in a selective and persistent normalization of keloidal fibroblast collagen, glycosaminoglycan, and collagenase production in vitro

1989 • 178 citations

Mononuclear Cell-Conditioned Medium Containing Mononuclear Cell Factor (MCF), Homologous With Interleukin 1, Stimulates Collagen and Fibronectin Synthesis by Adherent Rheumatoid Synovial Cells: Effects of Prostaglandin E2 and Indomethacin

1985 • 165 citations

Differential effects of gamma-interferon on collagen and fibronectin gene expression.

1987 • 156 citations

Effects of Interferon-γ and Other Cytokines on Collagen Synthesis in Fetal Rat Bone Cultures*

1987 • 154 citations

Alteration of Hypertrophic Scars Induced by Mechanical Pressure

1975 • 151 citations

Immune interferon suppresses levels of procollagen mRNA and type II collagen synthesis in cultured human articular and costal chondrocytes.

1986 • 151 citations

Inhibition of collagen synthesis by mononuclear cell supernates.

1979 • 142 citations

Lymphocyte modulation of fibroblast function in vitro: stimulation and inhibition of collagen production by different effector molecules.

1984 • 139 citations

The local treatment of hypertrophic scars and keloids with topical retinoic acid

1980 • 137 citations

Influences of gamma interferon on synovial fibroblast-like cells. Ia induction and inhibition of collagen synthesis.

1985 • 134 citations

Transcriptional control of human diploid fibroblast collagen synthesis by γ-interferon

1984 • 132 citations

Generalized Morphea

1972 • 115 citations

Genetic studies on keloid.

1975 • 113 citations

The Role of Pressure Therapy in Management of Earlobe Keloids

1978 • 110 citations

Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor-α production in keratinocytes cultured from psoriatic lesions

1989 • 109 citations

Inhibition of excessive scleroderma fibroblast collagen production by recombinant γ‐interferon: Association with a coordinate decrease in types I and III procollagen messenger RNA levels

1986 • 106 citations

Recombinant interferon-γ in the treatment of systemic sclerosis

1989 • 104 citations

Modulation of fibroblast growth by a lymphokine of human T cell continuous T cell line origin.

1983 • 103 citations

Postoperative irradiation in the prevention of keloids

1976 • 101 citations

The Systemic Administration of Gamma Interferon Inhibits Collagen Synthesis and Acute Inflammation in a Murine Skin Wounding Model

1989 • 94 citations

Heredity of keloids; review of the literature and report of a family with multiple keloids in five generations.

1956 • 91 citations

Interferon in suction blister fluid from psoriatic lesions

1983 • 89 citations

Ameliorating effect of murine interferon gamma on bleomycin-induced lung collagen fibrosis in mice

1986 • 88 citations

Differential regulation of glycosaminoglycan, fibronectin, and collagenase production in cultured human dermal fibroblasts by interferon-alpha,-beta, and-gamma

1989 • 87 citations

Immune interferon inhibits collagen synthesis by rheumatoid synovial cells associated wth decreaded levels of the procollagen mRNAs(FEBS 2156)

1985 • 83 citations

Scleroderma

1983 • 74 citations

The Combined Use of Cryosurgery and Intralesional Injections of Suspensions of Fluorinated Adrenocorticosteroids for Reducing Keloids and Hypertrophic Scars

1979 • 73 citations

Effectiveness of silastic sheet coverage in the treatment of scar keloid (hypertrophic scar)

1988 • 68 citations

Interferon-α and interferon-γ reduce excessive collagen synthesis and procollagen mRNA levels of scleroderma fibroblasts in culture

1988 • 65 citations

Keloid scars: A new method of treatment combining surgery with interstitial radiotherapy

1976 • 62 citations

Regulation of Collagen Synthesis

1982 • 57 citations

SPONGE FIXATION METHOD FOR TREATMENT OF EARLY SCARS

1968 • 57 citations

Early post-operative irradiation in the treatment of keloid scars

1965 • 53 citations

Scar Formation: Physiology and Pathological States

1984 • 49 citations

An experience in treating five hundred and one patients with keloids.

1974 • 49 citations

The biology of interferon actions

1988 • 48 citations

Keloid Scars: Analysis of 89 Patients

1970 • 45 citations

Lymphokine/Monokine Inhibition of Fibroblast Proliferation and Collagen Production: Role in Progressive Systemic Sclerosis (PSS)

1984 • 41 citations

Immune modulation of connective tissue functions: Studies on the production of collagen synthesis inhibitory factor by populations of human peripheral blood mononuclear cells

1982 • 24 citations

Regulation of growth of human diploid fibrobalasts by factors elaborated by activated lymphoid cells

1982 • 24 citations