TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

1996 • 2,320 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-β Signal Transduction

1995 • 1,318 citations

Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide

1985 • 1,191 citations

Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways

1996 • 899 citations

Receptor-associated Mad homologues synergize as effectors of the TGF-β response

1996 • 874 citations

MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma

1996 • 855 citations

TGFβ Signaling: Receptors, Transducers, and Mad Proteins

1996 • 840 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Physiological Actions and Clinical Applications of Transforming Growth Factor-β (TGF-β)

1993 • 755 citations

MADR2 Is a Substrate of the TGFβ Receptor and Its Phosphorylation Is Required for Nuclear Accumulation and Signaling

1996 • 740 citations

MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways

1996 • 710 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

A human Mad protein acting as a BMP-regulated transcriptional activator

1996 • 674 citations

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.

1995 • 672 citations

The antigenic index: a novel algorithm for predicting antigenic determinants

1988 • 655 citations

Characterization of Type I Receptors for Transforming Growth Factor-β and Activin

1994 • 558 citations

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components.

1996 • 528 citations

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects.

1995 • 510 citations

Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts.

1984 • 477 citations

Xenopus Mad Proteins Transduce Distinct Subsets of Signals for the TGFβ Superfamily

1996 • 432 citations

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway.

1996 • 351 citations

Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta.

1994 • 324 citations

Mad-related genes in the human

1996 • 308 citations

TGF-β-receptor-mediated signaling

1994 • 274 citations

Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors

1996 • 250 citations

Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals.

1996 • 197 citations

Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor

1996 • 172 citations

Identification of Smad2, a Human Mad-related Protein in the Transforming Growth Factor β Signaling Pathway

1997 • 168 citations

Regulation of transforming growth factor β- and activin-induced transcription by mammalian Mad proteins

1996 • 162 citations

Intracellular signalling: The Mad way to do it

1996 • 162 citations

Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.

1996 • 146 citations

DPC4 (SMAD4) mediates transforming growth factor-β1 (TGF-β1) induced growth inhibition and transcriptional response in breast tumour cells

1997 • 134 citations

Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor beta receptor kinases.

1995 • 116 citations

Serine Phosphorylation, Chromosomal Localization, and Transforming Growth Factor-β Signal Transduction by Human

1996 • 89 citations

The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation

1997 • 72 citations

Biological effects and binding properties of transforming growth factor-β on human oral squamous cell carcinoma cells

1990 • 51 citations

TGF-( -receptor-mediated signaling

1994 • 46 citations