Genomics in multiple sclerosis—Current state and future directions

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

2001 • 4,058 citations

Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination

2000 • 3,258 citations

IMMUNOLOGY OF MULTIPLE SCLEROSIS

2005 • 2,099 citations

Expression profiling using cDNA microarrays

1999 • 1,689 citations

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

2002 • 1,644 citations

Individuality and variation in gene expression patterns in human blood

2003 • 788 citations

THE INFLUENCE OF THE PROINFLAMMATORY CYTOKINE, OSTEOPONTIN, ON AUTOIMMUNE DEMYELINATING DISEASE

2002 • 729 citations

APPLICATIONS OF DNA MICROARRAYS IN BIOLOGY

2005 • 382 citations

Development of biomarkers in multiple sclerosis

2004 • 296 citations

Analysis of gene expression in multiple sclerosis lesions using cDNA microarrays

1999 • 245 citations

Molecular Changes in Normal Appearing White Matter in Multiple Sclerosis are Characteristic of Neuroprotective Mechanisms Against Hypoxic Insult

2003 • 225 citations

Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease

2003 • 214 citations

Cutting Edge: Molecular Portrait of Human Autoimmune Disease

2002 • 206 citations

Complex immunomodulatory effects of interferon‐β in multiple sclerosis include the upregulation of T helper 1‐associated marker genes

2001 • 179 citations

Expression profiling identifies responder and non‐responder phenotypes to interferon‐β in multiple sclerosis

2003 • 170 citations

Blood transcriptional signatures of multiple sclerosis: Unique gene expression of disease activity

2004 • 159 citations

Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation

2004 • 153 citations

Microarray analysis of gene expression in multiple sclerosis and EAE identifies 5-lipoxygenase as a component of inflammatory lesions

2001 • 151 citations

cDNA microarray analysis in multiple sclerosis lesions: detection of genes associated with disease activity

2003 • 147 citations

Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis

2003 • 135 citations

Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis

2005 • 128 citations

Microarrays: the use of oligonucleotides and cDNA for the analysis of gene expression

2003 • 128 citations

Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis

2005 • 122 citations

Genomic Effects of IFN-β in Multiple Sclerosis Patients

2003 • 120 citations

Autoimmunity gene expression portrait: specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus

2004 • 119 citations

Gene expression profiling of the nervous system in murine experimental autoimmune encephalomyelitis

2001 • 114 citations

In vivo gene expression revealed by cDNA arrays: the pattern in relapsing–remitting multiple sclerosis patients compared with normal subjects

2001 • 110 citations

Gene expression analysis suggests that 1,25-dihydroxyvitamin D₃reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosis

2004 • 103 citations

Multiple sclerosis as a generalized CNS disease—comparative microarray analysis of normal appearing white matter and lesions in secondary progressive MS

2004 • 100 citations

Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis

2005 • 98 citations

Combinatorial Peptide Libraries and Biometric Score Matrices Permit the Quantitative Analysis of Specific and Degenerate Interactions Between Clonotypic TCR and MHC Peptide Ligands

2001 • 95 citations

Regulation of gene expression in experimental autoimmune encephalomyelitis indicates early neuronal dysfunction

2003 • 90 citations

Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis

2004 • 80 citations

Microarray analysis identifies interferon β-regulated genes in multiple sclerosis

2003 • 76 citations

Dual phase regulation of experimental allergic encephalomyelitis by platelet-activating factor

2005 • 76 citations

Genomic scale profiling of autoimmune inflammation in the central nervous system: the nervous response to inflammation

2002 • 73 citations

Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin

2004 • 73 citations

Gene expression profiling of relevant biomarkers for treatment evaluation in multiple sclerosis

2004 • 72 citations

MRI as a marker for disease heterogeneity in multiple sclerosis

2005 • 69 citations

Microarray detection of E2F pathway activation and other targets in multiple sclerosis peripheral blood mononuclear cells

2004 • 66 citations

Evaluation of the Effects of 17β-Estradiol (17β-E2) on Gene Expression in Experimental Autoimmune Encephalomyelitis Using DNA Microarray

2002 • 61 citations

Modular Transcriptional Activity Characterizes the Initiation and Progression of Autoimmune Encephalomyelitis

2005 • 39 citations

CNS gene expression pattern associated with spontaneous experimental autoimmune encephalomyelitis

2003 • 27 citations

Understanding Autoimmune Mechanisms in Multiple Sclerosis Using Gene Expression Microarrays: Treatment Effect and Cytokine‐related Pathways

2004 • 25 citations

Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process

2004 • 24 citations

Analysis of Gene Expression in MOG-Induced Experimental Autoimmune Encephalomyelitis After Treatment <SMALL>W</SMALL>ith a Novel Brain-Penetrating Antioxidant

2005 • 21 citations

Suppression of immune system genes by methylprednisolone in exacerbations of multiple sclerosis

2004 • 18 citations

Evaluation of the Effects of 17 -Estradiol (17 -E2) on Gene Expression in Experimental Autoimmune Encephalomyelitis Using DNA Microarray

2002 • 12 citations

Exploiting genotypic differences to identify genes important for EAE development

2005 • 12 citations