Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

2000 • 9,712 citations

Genetic Dissection of Complex Traits

1994 • 3,497 citations

Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination

2000 • 3,258 citations

Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

2001 • 2,626 citations

Anesthesiology

1997 • 2,182 citations

Molecular classification of cutaneous malignant melanoma by gene expression profiling

2000 • 2,011 citations

Multiple sclerosis

2002 • 1,678 citations

Immunological Aspects of Demyelinating Diseases

1992 • 1,021 citations

The HLA System

2000 • 881 citations

Molecular Chaperones Hsp90 and Hsp70 Deliver Preproteins to the Mitochondrial Import Receptor Tom70

2003 • 836 citations

Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis

1991 • 794 citations

Individuality and variation in gene expression patterns in human blood

2003 • 788 citations

Prolonged activation of jun and collagenase genes by tumour necrosis factor-α

1989 • 726 citations

CD27 is required for generation and long-term maintenance of T cell immunity

2000 • 726 citations

Inherited Human Caspase 10 Mutations Underlie Defective Lymphocyte and Dendritic Cell Apoptosis in Autoimmune Lymphoproliferative Syndrome Type II

1999 • 631 citations

A genetic basis for familial aggregation in multiple sclerosis

1995 • 626 citations

Partial T cell signaling: Altered phospho-? and lack of zap70 recruitment in APL-induced T cell anergy

1994 • 608 citations

Delineating the Genetic Basis of Systemic Lupus Erythematosus

2001 • 562 citations

Rapid exchange of histone H1.1 on chromatin in living human cells

2000 • 405 citations

Control of mRNA Decay by Heat Shock-Ubiquitin-Proteasome Pathway

1999 • 395 citations

Evidence for genetic basis of multiple sclerosis

1996 • 355 citations

Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array

2003 • 298 citations

Platelet-activating Factor Acetylhydrolases

1997 • 274 citations

Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies

2001 • 253 citations

Age–adjusted recurrence risks for relatives of patients with multiple sclerosis

1996 • 227 citations

Cutting Edge: Molecular Portrait of Human Autoimmune Disease

2002 • 206 citations

Genetic Protection from the Inflammatory Disease Type 1 Diabetes in Humans and Animal Models

2001 • 205 citations

Mice Lacking the p53-Effector Gene Gadd45a Develop a Lupus-Like Syndrome

2002 • 189 citations

Complex immunomodulatory effects of interferon‐β in multiple sclerosis include the upregulation of T helper 1‐associated marker genes

2001 • 179 citations

Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia

1999 • 179 citations

IL-2 negatively regulates IL-7 receptor α chain expression in activated T lymphocytes

2002 • 176 citations

Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiae.

1990 • 169 citations

Small sample issues for microarray‐based classification

2001 • 157 citations

Genetics of multiple sclerosis [published erratum appears in Hum Mol Genet 1997 Nov;6(12):2189]

1997 • 151 citations

ZBP-89, a Krüppel-Like Zinc Finger Protein, Inhibits Epidermal Growth Factor Induction of the Gastrin Promoter

1996 • 128 citations

In vivo gene expression revealed by cDNA arrays: the pattern in relapsing–remitting multiple sclerosis patients compared with normal subjects

2001 • 110 citations

Analysis of γc-Family Cytokine Target Genes

2003 • 95 citations

Susceptibility for multiple sclerosis is determined, in part, by inheritance of a 175-kb region of the TcR Vβ chain locus and HLA class II genes

1993 • 94 citations

Strong Feature Sets from Small Samples

2002 • 91 citations

The genetic analysis of multiple sclerosis

1997 • 77 citations

The genetic epidemiology of multiple sclerosis

1999 • 70 citations

Cell-cycle regulation in immunity, tolerance and autoimmunity

2000 • 68 citations

The immune response to Mycobacterial 70-kDa heat shock proteins frequently involves autoreactive T cells and is quantitatively disregulated in multiple sclerosis

1996 • 62 citations

Genetic epidemiology of multiple sclerosis: A survey

1994 • 46 citations

The complex genetic aetiology of multiple sclerosis.

2000 • 44 citations

The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization.

1992 • 44 citations

Short cut to disease genes

2001 • 11 citations

Conditional Knockdown of Proteasomes Results in Cell-cycle Arrest and Enhanced Expression of Molecular Chaperones Hsp70 and Hsp40 in Chicken DT40 Cells

2003 • 9 citations