APPLICATIONS OF DNA MICROARRAYS IN BIOLOGY

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

2002 • 12,185 citations

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

2000 • 9,712 citations

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

1995 • 9,575 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

2002 • 6,428 citations

Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization

1998 • 4,811 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

A gene atlas of the mouse and human protein-encoding transcriptomes

2004 • 3,443 citations

Use of proteomic patterns in serum to identify ovarian cancer

2002 • 3,227 citations

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

2000 • 3,126 citations

Light-Directed, Spatially Addressable Parallel Chemical Synthesis

1991 • 2,692 citations

Functional Discovery via a Compendium of Expression Profiles

2000 • 2,581 citations

Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

2003 • 2,500 citations

Variance stabilization applied to microarray data calibration and to the quantification of differential expression

2002 • 2,340 citations

Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network

2001 • 2,058 citations

Genome-Wide Location and Function of DNA Binding Proteins

2000 • 1,720 citations

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

2002 • 1,644 citations

Comparative Genomics of BCG Vaccines by Whole-Genome DNA Microarray

1999 • 1,537 citations

Genetics of gene expression surveyed in maize, mouse and man

2003 • 1,518 citations

Accessing Genetic Information with High-Density DNA Arrays

1996 • 1,511 citations

Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

2003 • 1,406 citations

Analysis of Variance for Gene Expression Microarray Data

2000 • 1,339 citations

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

2001 • 1,297 citations

Amplified RNA synthesized from limited quantities of heterogeneous cDNA.

1990 • 1,258 citations

An Information-Intensive Approach to the Molecular Pharmacology of Cancer

1997 • 1,177 citations

A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization.

1996 • 1,146 citations

Inferring Genetic Networks and Identifying Compound Mode of Action via Expression Profiling

2003 • 1,130 citations

ArrayExpress--a public repository for microarray gene expression data at the EBI

2004 • 1,104 citations

Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs

2004 • 1,079 citations

Fundamentals of experimental design for cDNA microarrays

2002 • 1,070 citations

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

2004 • 1,057 citations

DNA Microarray Technology: Devices, Systems, and Applications

2002 • 1,040 citations

Analysis of gene expression in single live neurons.

1992 • 944 citations

A combined algorithm for genome-wide prediction of protein function

1999 • 921 citations

Single-target molecule detection with nonbleaching multicolor optical immunolabels

2000 • 877 citations

Signaling and Circuitry of Multiple MAPK Pathways Revealed by a Matrix of Global Gene Expression Profiles

2000 • 867 citations

Improved Nearest-Neighbor Parameters for Predicting DNA Duplex Stability

1996 • 829 citations

Replication Dynamics of the Yeast Genome

2001 • 811 citations

Microarray-based detection and genotyping of viral pathogens

2002 • 792 citations

ArrayExpress--a public repository for microarray gene expression data at the EBI

2003 • 761 citations

Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array

1999 • 725 citations

Gene expression profiles of laser-captured adjacent neuronal subtypes

1999 • 708 citations

Advanced multiplexed analysis with the FlowMetrix system.

1997 • 700 citations

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

2000 • 699 citations

A Gene Expression Map for Caenorhabditis elegans

2001 • 674 citations

Complementary Profiling of Gene Expression at the Transcriptome and Proteome Levels in Saccharomyces cerevisiae

2002 • 668 citations

Drug target validation and identification of secondary drug target effects using DNA microarrays

1998 • 663 citations

Large-scale temporal gene expression mapping of central nervous system development

1998 • 647 citations

Highly Parallel SNP Genotyping

2003 • 643 citations

Advanced multiplexed analysis with the FlowMetrixTM system

1997 • 623 citations

Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects

2001 • 584 citations

Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar–coding strategy

1996 • 570 citations

Statistical Analysis of Gene Expression Microarray Data

2003 • 567 citations

Resequencing and mutational analysis using oligonucleotide microarrays

1999 • 517 citations

Widespread aneuploidy revealed by DNA microarray expression profiling

2000 • 490 citations

Microarray Deacetylation Maps Determine Genome-Wide Functions for Yeast Histone Deacetylases

2002 • 467 citations

Microarray Analysis of Drosophila Development During Metamorphosis

1999 • 465 citations

A variance-stabilizing transformation for gene-expression microarray data

2002 • 460 citations

Representational Oligonucleotide Microarray Analysis: A High-Resolution Method to Detect Genome Copy Number Variation

2003 • 452 citations

Experimental annotation of the human genome using microarray technology

2001 • 446 citations

Viral Discovery and Sequence Recovery Using DNA Microarrays

2003 • 446 citations

Post-analysis follow-up and validation of microarray experiments

2002 • 444 citations

Evolutionary genomics of Staphylococcus aureus : Insights into the origin of methicillin-resistant strains and the toxic shock syndrome epidemic

2001 • 441 citations

Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks

2002 • 429 citations

Clustering of Hepatotoxins Based on Mechanism of Toxicity Using Gene Expression Profiles

2001 • 384 citations

Decoding Randomly Ordered DNA Arrays

2004 • 327 citations

Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment

2003 • 326 citations

Proteomics

2003 • 318 citations

Computation-Based Discovery of Related Transcriptional Regulatory Modules and Motifs Using an Experimentally Validated Combinatorial Model

2002 • 316 citations

Parallel Genotyping of Human SNPs Using Generic High-density Oligonucleotide Tag Arrays

2000 • 309 citations

Sequence-specific identification of 18 pathogenic microorganisms using microarray technology

2002 • 287 citations

High-Throughput Variation Detection and Genotyping Using Microarrays

2001 • 277 citations

Microarray Analysis of Microbial Virulence Factors

2001 • 256 citations

Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data

2004 • 256 citations

DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling

2002 • 239 citations

Hybridization Enhancement Using Cavitation Microstreaming

2003 • 237 citations

Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array

1999 • 233 citations

The Human MitoChip: A High-Throughput Sequencing Microarray for Mitochondrial Mutation Detection

2004 • 233 citations

Selection of optimal DNA oligos for gene expression arrays

2001 • 229 citations

Medical applications of microarray technologies: a regulatory science perspective

2002 • 227 citations

Effects of Atmospheric Ozone on Microarray Data Quality

2003 • 222 citations

Chips with everything: DNA microarrays in infectious diseases

2004 • 221 citations

A novel, sensitive detection system for high-density microarrays using dendrimer technology

2000 • 217 citations

Using DNA Microarrays to Study Host-Microbe Interactions

2000 • 214 citations

A statistical method for finding transcription factor binding sites.

2000 • 207 citations

Solving the riddle of the bright mismatches: Labeling and effective binding in oligonucleotide arrays

2003 • 202 citations

A fiber-optic DNA biosensor microarray for the analysis of gene expression

1996 • 192 citations

The consequences of chromosomal aneuploidy on gene expression profiles in a cell line model for prostate carcinogenesis.

2001 • 186 citations

A Versatile Assay for High-Throughput Gene Expression Profiling on Universal Array Matrices

2004 • 183 citations

Biomedical informatics for proteomics

2003 • 183 citations

Signal amplification by rolling circle amplification on DNA microarrays

2001 • 183 citations

Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro

2003 • 183 citations

Microarray Bioinformatics

2003 • 180 citations

Microarrays for an Integrative Genomics

2002 • 178 citations

Microarray reality checks in the context of a complex disease

2004 • 175 citations

Cystic fibrosis mutation detection by hybridization to light-generated DNA probe arrays

1996 • 169 citations

Universal Reference RNA as a standard for microarray experiments

2004 • 165 citations

Absolute mRNA concentrations from sequence-specific calibration of oligonucleotide arrays

2003 • 162 citations

An evaluation of tyramide signal amplification and archived fixed and frozen tissue in microarray gene expression analysis

2002 • 149 citations

Iterative Group Analysis (iGA): A simple tool to enhance sensitivity and facilitate interpretation of microarray experiments

2004 • 146 citations

Nucleic Acid Amplification Strategies for DNA Microarray-Based Pathogen Detection

2004 • 145 citations

In vitro sliding of actin filaments labelled with single quantum dots

2004 • 139 citations

Pattern Recognition Techniques in Microarray Data Analysis

2002 • 139 citations

Use of hybridization kinetics for differentiating specific from non-specific binding to oligonucleotide microarrays

2002 • 133 citations

Surface electrostatic effects in oligonucleotide microarrays: Control and optimization of binding thermodynamics

2003 • 121 citations

Predicting Splice Variant from DNA Chip Expression Data

2001 • 121 citations

Statistical design of reverse dye microarrays

2003 • 118 citations

Identification of co-regulated genes through Bayesian clustering of predicted regulatory binding sites

2003 • 103 citations

Regulation of biotechnology: will we ever 'freely' trade GMOs?

2002 • 102 citations

Microarray analysis of evolution of RNA viruses: Evidence of circulation of virulent highly divergent vaccine-derived polioviruses

2003 • 100 citations

Microarray-BasedIdentification of Thermophilic Campylobacter jejuni , C.coli , C. lari , and C.upsaliensis

2003 • 97 citations

Evaluation of the Performance of a p53 Sequencing Microarray Chip Using 140 Previously Sequenced Bladder Tumor Samples

2000 • 93 citations

Microarray standard data set and figures of merit for comparing data processing methods and experiment designs

2003 • 91 citations

Oligonucleotide hybridization studied by a surface plasmon diffraction sensor (SPDS)

2004 • 89 citations

Analysis of variance components in gene expression data

2004 • 88 citations

ArrayExpress: a public database of gene expression data at EBI

2003 • 86 citations

Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing

2003 • 85 citations

Microarray results improve significantly as hybridization approaches equilibrium

2004 • 80 citations

Base pair mismatch recognition using plasmon resonant particle labels

2002 • 74 citations

Microarray analysis of erythromycin resistance determinants

2003 • 72 citations

Guide to Analysis of DNA Microarray Data

2004 • 69 citations

Guide to analysis of DNA microarray data

2004 • 66 citations

Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver

2004 • 61 citations

Single primer amplification (SPA) of cDNA for microarray expression analysis

2003 • 61 citations

Variance-stabilizing transformations for two-color microarrays

2004 • 57 citations

Microarray analysis of gene expression during the cell cycle.

2003 • 55 citations

Regulatory motif finding by logic regression

2004 • 53 citations

rPCR: a powerful tool for random amplification of whole RNA sequences.

1993 • 49 citations

DNA microarray data and contextual analysis of correlation graphs

2003 • 44 citations

Temporal and spatial gene expression patterns after experimental stroke in a rat model and characterization of PC4, a potential regulator of transcription

2003 • 42 citations

Expression profiling of small cellular samples in cancer: less is more

2004 • 38 citations

Arrays of Arrays for High-Throughput Gene Expression Profiling

2001 • 37 citations

Expression profiling using a hexamer-based universal microarray

2004 • 33 citations

How well do we understand the clusters found in microarray data?

2002 • 32 citations

Simulating the Schrödinger functional with two pseudo-fermions

2003 • 29 citations

Arrays of Arrays for High-Throughput Gene Expression Profiling

2001 • 29 citations

TEAM: a tool for the integration of expression, and linkage and association maps

2004 • 28 citations

DNA Microarrays: Gene Expression Applications

2001 • 28 citations

Dextran sulfate provides a quantitative and quick microarray hybridization reaction

2004 • 26 citations

3′-End cDNA Pool Suitable for Differential Display from a Small Number of Cells

1998 • 20 citations

Optimizing stringency for expression microarrays

2003 • 17 citations

A microarray platform comparison for neuroscience applications

2003 • 16 citations

Cystic fibrosis mutation detection by hybridization to light‐generated DNA probe arrays

1996 • 13 citations

DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling

2003 • 12 citations

Genomics and neurological phenotypes: applications for seizure-induced damage

2002 • 9 citations

Roche's microarray tests US FDA's diagnostic policy

2003 • 8 citations

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2002 • 3 citations

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2002 • 2 citations

Record of a fatal oomycotic disease of the fresh water fish Anabas cobojius in India caused by Aplanes braunii.

2003 • 1 citations

International news

2003 • 1 citations

Commentary

2003 • 1 citations