Analysis of Gene Expression in MOG-Induced Experimental Autoimmune Encephalomyelitis After Treatment <SMALL>W</SMALL>ith a Novel Brain-Penetrating Antioxidant

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

Axonal Transection in the Lesions of Multiple Sclerosis

1998 • 4,007 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

2002 • 1,644 citations

Axonal damage in acute multiple sclerosis lesions

1997 • 1,543 citations

Eta-1 (Osteopontin): An Early Component of Type-1 (Cell-Mediated) Immunity

2000 • 1,104 citations

Osteopontin: a protein with diverse functions

1993 • 1,082 citations

Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

1986 • 1,078 citations

THE INFLUENCE OF THE PROINFLAMMATORY CYTOKINE, OSTEOPONTIN, ON AUTOIMMUNE DEMYELINATING DISEASE

2002 • 729 citations

Flexible Structures of SIBLING Proteins, Bone Sialoprotein, and Osteopontin

2001 • 639 citations

The role of oxidative stress in the pathogenesis of multiple sclerosis: The need for effective antioxidant therapy

2004 • 610 citations

Brain lipid-binding protein (BLBP): A novel signaling system in the developing mammalian CNS

1994 • 570 citations

Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains

1994 • 570 citations

T cell gelatinases mediate basement membrane transmigration in vitro.

1995 • 507 citations

HISTOCOMPATIBILITY DETERMINANTS IN MULTIPLE SCLEROSIS, WITH SPECIAL REFERENCE TO CLINICAL COURSE

1973 • 472 citations

CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation

2002 • 395 citations

Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex

1997 • 366 citations

Osteopontin: a key cytokine in cell‐mediated and granulomatous inflammation

2000 • 353 citations

Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease

2002 • 325 citations

Ciliary Neurotrophic Factor (CNTF) Enhances Myelin Formation: A Novel Role for CNTF and CNTF-Related Molecules

2002 • 244 citations

Myelin/oligodendrocyte glycoprotein is a member of a subset of the immunoglobulin superfamily encoded within the major histocompatibility complex.

1993 • 221 citations

N-acetylcysteine amide, a novel cell-permeating thiol, restores cellular glutathione and protects human red blood cells from oxidative stress

2004 • 220 citations

Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease

2003 • 214 citations

Extracellular Matrix‐Degrading Proteinases in the Nervous System

1994 • 208 citations

Ligand Specificity of Brain Lipid-binding Protein

1996 • 198 citations

Deimination of Myelin Basic Protein. 1. Effect of Deimination of Arginyl Residues of Myelin Basic Protein on Its Structure and Susceptibility to Digestion by Cathepsin D

2000 • 189 citations

Putting Magnetic Resonance Spectroscopy Studies in Context: Axonal Damage and Disability in Multiple Sclerosis

1998 • 182 citations

Reactive oxygen species are required for the phagocytosis of myelin by macrophages

1998 • 177 citations

Osteopontin Function in Pathology: Lessons from Osteopontin-Deficient Mice

1999 • 175 citations

Autoimmune Pathogenesis of Multiple Sclerosis: Role of Autoreactive T Lymphocytes and New Immunotherapeutic Strategies

1997 • 159 citations

Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)‐derived peptide: Preliminary analysis of MOG T cell epitopes

1995 • 157 citations

Interleukin‐6 functions in autoimmune encephalomyelitis: a study in gene‐targeted mice

1998 • 156 citations

A low molecular weight copper chelator crosses the blood–brain barrier and attenuates experimental autoimmune encephalomyelitis

2004 • 125 citations

Elevated osteopontin levels in active relapsing‐remitting multiple sclerosis

2003 • 122 citations

Chapter 1 Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways

1998 • 119 citations

Gene expression profiling of the nervous system in murine experimental autoimmune encephalomyelitis

2001 • 114 citations

Inflammatory Events at the Blood Brain Barrier: Regulation of Adhesion Molecules, Cytokines, and Chemokines by Reactive Nitrogen and Oxygen Species

1997 • 112 citations

Antioxidants, Redox-Regulated Transcription Factors, and Inflammation

1996 • 109 citations

Riluzole suppresses experimental autoimmune encephalomyelitis: implications for the treatment of multiple sclerosis

2003 • 102 citations

Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: The allele E3 is neuroprotective whereas E4 increases fatalities

2000 • 101 citations

Cathepsin S and an asparagine-specific endoprotease dominate the proteolytic processing of human myelin basic proteinin vitro

2001 • 97 citations

Regulation of gene expression in experimental autoimmune encephalomyelitis indicates early neuronal dysfunction

2003 • 90 citations

Multiple sclerosis: expression of molecules of the tumor necrosis factor ligand and receptor families in relationship to the demyelinated plaque.

1998 • 80 citations

Clusterin expression by astrocytes is influenced by transforming growth factor β1 and heterotypic cell interactions

1995 • 75 citations

Axonal damage is reduced following glatiramer acetate treatment in C57/bl mice with chronic-induced experimental autoimmune encephalomyelitis

2003 • 75 citations

Genomic scale profiling of autoimmune inflammation in the central nervous system: the nervous response to inflammation

2002 • 73 citations

Increased cathepsin B activity in multiple sclerosis brain

1995 • 70 citations

A novel thiol antioxidant that crosses the blood brain barrier protects dopaminergic neurons in experimental models of Parkinson's disease

2005 • 69 citations

Combined magnetization transfer and proton spectroscopic imaging in the assessment of pathologic brain lesions in multiple sclerosis.

1999 • 58 citations

Retinoic acid promotes the development of Th2-like human myelin basic protein-reactive T cells

2002 • 54 citations

Regulation of Myelin Oligodendrocyte Glycoprotein in Different Species throughout Development

1997 • 45 citations

Elevation of human cerebrospinal fluid clusterin concentration is associated with acute neuropathology

1993 • 40 citations

E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha

1996 • 38 citations

Myelin-associated oligodendrocytic basic protein modulates the arrangement of radial growth of the axon and the radial component of myelin

2001 • 37 citations

Increased cathepsin B activity in peripheral blood mononuclear cells of multiple sclerosis patients

1994 • 33 citations

Anti-inflammatory strategies to prevent axonal injury in multiple sclerosis

2002 • 27 citations

Activation of a novel microglial gene encoding a lysosomal membrane protein in response to neuronal apoptosis

2001 • 26 citations

Polygenic control of experimental allergic encephalomyelitis in Biozzi ABH and BALB/c mice

1997 • 24 citations

Prothymosin-α enhances HLA-DR antigen expression on monocytes from patients with multiple sclerosis

1990 • 24 citations

Phenotypic analysis of mice deficient in the major myelin protein MOBP, and evidence for a novel Mobp isoform

2002 • 23 citations

Bax-ablation attenuates experimental autoimmune encephalomyelitis in mice

2004 • 22 citations

Gene-expression profiling of experimental autoimmune encephalomyelitis.

2002 • 15 citations

Multiple sclerosis: from basic immunopathology to immune intervention

2002 • 5 citations