Low-dose Photon and Simulated Solar Particle Event Proton Effects on Foxp3⁺T Regulatory Cells and other Leukocytes

Aviat space environ med

1992 • 7,493 citations

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

2010 • 5,969 citations

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.

1995 • 5,124 citations

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

2005 • 2,667 citations

Mast cells

1997 • 1,636 citations

CD4+CD25+ TR Cells Suppress Innate Immune Pathology Through Cytokine-dependent Mechanisms

2003 • 748 citations

Mast cells are essential intermediaries in regulatory T-cell tolerance

2006 • 742 citations

Regulatory T cells in cancer

2006 • 717 citations

Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II

2004 • 359 citations

CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection

2008 • 352 citations

Low-Dose Ionizing Radiation Decreases the Frequency of Neoplastic Transformation to a Level below the Spontaneous Rate in C3H 10T1/2 Cells

1996 • 287 citations

An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme1

2006 • 286 citations

Neuroprotective autoimmunity: Naturally occurring CD4 ⁺ CD25 ⁺ regulatory T cells suppress the ability to withstand injury to the central nervous system

2002 • 261 citations

TGF‐β: a mobile purveyor of immune privilege

2006 • 227 citations

Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9–mediated progenitor cell mobilization

2005 • 223 citations

Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation

2009 • 195 citations

Regulatory T Cells and Human Disease

2007 • 188 citations

T-Regulatory Cells Shift from a Protective Anti-Inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis

2009 • 184 citations

Low dose, low-LET ionizing radiation-induced radioadaptation and associated early responses in unirradiated cells

2002 • 182 citations

Long-lasting alterations of the immune system by ionizing radiation exposure: Implications for disease development among atomic bomb survivors

2007 • 177 citations

DNA damage response pathway in radioadaptive response

2002 • 167 citations

Low-Dose Irradiation Alters the Transcript Profiles of Human Lymphoblastoid Cells Including Genes Associated with Cytogenetic Radioadaptive Response

2005 • 138 citations

Control of Immune Pathology by Regulatory T Cells

2003 • 136 citations

Residential Radon and Lung Cancer Risk in a High-exposure Area of Gansu Province, China

2002 • 123 citations

CD4+CD25+ T Regulatory Cells Dominate Multiple Immune Evasion Mechanisms in Early but Not Late Phases of Tumor Development in a B Cell Lymphoma Model

2007 • 122 citations

Cancer Control Related to Stimulation of Immunity by Low-Dose Radiation

2007 • 105 citations

Interplanetary Crew Dose Rates for the August 1972 Solar Particle Event

2000 • 93 citations

Radiation-induced bystander effects and adaptive responses—the Yin and Yang of low dose radiobiology?

2004 • 88 citations

Adipose Tissue Sensitivity to Radiation Exposure

2008 • 88 citations

Mast cells as modulators of T‐cell responses

2007 • 83 citations

Mast Cells Down-Regulate CD4+CD25+ T Regulatory Cell Suppressor Function via Histamine H1 Receptor Interaction

2009 • 76 citations

Mast Cells: Not Only in Allergy

2006 • 71 citations

Suppressing Effect of Low-Dose Gamma-Ray Irradiation on Collagen-Induced Arthritis

2008 • 67 citations

Radiation countermeasure agents: an update

2009 • 66 citations

Low-dose radiation risk extrapolation fallacy associated with the linear-no-threshold model

2008 • 64 citations

Low‐dose γ‐irradiation promotes survival of injured neurons in the central nervous system via homeostasis‐driven proliferation of T cells

2004 • 63 citations

Gamma irradiation alters the phenotype and function of CD4⁺CD25⁺ regulatory T cells

2009 • 57 citations

Augmentation of innate immunity by low-dose irradiation

2006 • 55 citations

Is Chronic Radiation an Effective Prophylaxis Against Cancer

2004 • 52 citations

Variable hematopoietic responses to acute photons, protons and simulated solar particle event protons.

2008 • 50 citations

Evidence for Radiation Hormesis after In Vitro Exposure of Human Lymphocytes to Low Doses of Ionizing Radiation

2008 • 47 citations

Whole-body irradiation and long-term modification of bone marrow-derived cell populations by low- and high-LET radiation.

2007 • 42 citations

Effects of Gamma Radiation on FcεRI and TLR-Mediated Mast Cell Activation

2007 • 41 citations

Low-Dose Photons Modify Liver Response to Simulated Solar Particle Event Protons

2008 • 41 citations

Repeated 0.5-Gy Gamma Irradiation Attenuates Autoimmune Disease in MRL-lpr/lprMice with Suppression of CD3⁺CD4⁻CD8⁻B220⁺T-Cell Proliferation and with Up-regulation of CD4⁺CD25⁺Foxp3⁺Regulatory T Cells

2007 • 39 citations

La prévention du cancer et la relation dose–effet : l’effet cancérogène des rayonnements ionisants

2009 • 37 citations

Effects of proton and gamma radiation on lymphocyte populations and acute response to antigen.

2000 • 36 citations

Low Dose, Low Dose Rate Photon Radiation Modifies Leukocyte Distribution and Gene Expression in CD4+ T Cells

2009 • 35 citations

Acute Effects of Iron-Particle Radiation on Immunity. Part I: Population Distributions

2006 • 32 citations

Temporal Analysis of the October 1989 Proton Flare Using Computerized Anatomical Models

1993 • 31 citations

TP53 and TP53-Related Genes Associated with Protection from Apoptosis in the Radioadaptive Response

2007 • 30 citations

Low-dose ionizing radiation: induction of differential intracellular signalling possibly affecting intercellular communication

2005 • 30 citations

Response of Extracellular Matrix Regulators in Mouse Lung after Exposure to Photons, Protons and Simulated Solar Particle Event Protons

2009 • 28 citations

Differential Effects of Irradiation with Carbon Ions and X-Rays on Macrophage Function

2009 • 27 citations

Involvement of Intracellular Expression of FGF12 in Radiation-Induced Apoptosis in Mast Cells

2008 • 25 citations

Long-term effects of low-dose proton radiation on immunity in mice: shielded vs. unshielded.

2003 • 22 citations

Reassessment of the Cancer Mortality Risk among Hiroshima Atomic-Bomb Survivors Using a New Dosimetry System, ABS2000D, Compared with ABS93D

2002 • 18 citations

Simulation of a 36h solar particle event at LLUMC using a proton beam scanning system

2007 • 13 citations

An Approach to Estimate Radioadaptation from DSB Repair Efficiency

2009 • 8 citations