The Fas-Fas ligand system and other modulators of apoptosis in the cornea.

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

The Fas Death Factor

1995 • 4,070 citations

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1993 • 3,111 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Mechanisms and Genes of Cellular Suicide

1995 • 2,514 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

1995 • 1,346 citations

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma.

1986 • 1,118 citations

Genetic Control of Programmed Cell Death in Drosophila

1994 • 1,028 citations

Fas ligand mediates activation-induced cell death in human T lymphocytes.

1995 • 949 citations

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

1995 • 656 citations

Epithelial Injury Induces Keratocyte Apoptosis: Hypothesized Role for the Interleukin-1 System in the Modulation of Corneal Tissue Organization and Wound Healing

1996 • 573 citations

Human Fas ligand: gene structure, chromosomal location and species specificity

1994 • 435 citations

Programmed cell death in Caenorhabditis elegans

1994 • 379 citations

Delayed internucleosomal DNA fragmentation in programmed cell death

1993 • 222 citations

Fas-Mediated Apoptosis in Primary Cultured Mouse Hepatocytes

1994 • 202 citations

EGF, EGF receptor, basic FGF, TGF beta-1, and IL-1 alpha mRNA in human corneal epithelial cells and stromal fibroblasts.

1992 • 194 citations

Epidermal Growth Factor, Transforming Growth Factor Alpha, Transforming Growth Factor Beta, Acidic Fibroblast Growth Factor, Basic Fibroblast Growth Factor, and Interleukin-1 Proteins in the Cornea

1994 • 181 citations

Expression of Fas Antigen on Keratinocytes In Vivo and Induction of Apoptosis in Cultured Keratinocytes

1994 • 175 citations

Transforming growth factor-beta and interleukin-1 modulate metalloproteinase expression by corneal stromal cells.

1991 • 163 citations

Molecular controls of apoptosis: differentiation/growth arrest primary response genes, proto-oncogenes, and tumor suppressor genes as positive & negative modulators.

1994 • 153 citations

Characterization of human Fas gene. Exon/intron organization and promoter region.

1995 • 130 citations

Keratocyte Loss After Corneal Deepithelialization in Primates and Rabbits

1994 • 104 citations

Binding sites for human interleukin 1 α, gamma interferon and tumor necrosis factor on cultured fibroblasts of normal cornea and keratoconus

1991 • 90 citations

Distribution of apoptosis-mediating Fas antigen in human skin and effects of anti-Fas monoclonal antibody on human epidermal keratinocyte and squamous cell carcinoma cell lines

1994 • 81 citations

Interleukin 1 alpha mediates collagenase synthesis stimulated by phorbol 12-myristate 13-acetate

1994 • 76 citations

Involvement of Ca2+ in the Formation of High-Molecular-Weight DNA Fragments in Thymocyte Apoptosis

1994 • 74 citations

Stromal changes following removal of epithelium in rat cornea.

1988 • 70 citations

Apoptosis: physiologic cell death.

1994 • 61 citations

Molecular Characterization of the Gene for Human Interleukin-1β Converting Enzyme (IL1BC)

1994 • 45 citations

A Variant mRNA Species Encoding a Truncated Form of Fas Antigen in the Rat Liver

1994 • 42 citations

Glucocorticoid Receptor and Interleukin-1 Receptor Messenger RNA Expression in Corneal Cells

1994 • 25 citations

Transgenic mice in the study of cytokine function.

1993 • 22 citations