Chemokine and chemokine receptor expression in the central nervous system

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Chemokines — Chemotactic Cytokines That Mediate Inflammation

1998 • 3,660 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1998 • 2,496 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

A new class of membrane-bound chemokine with a CX3C motif

1997 • 1,964 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

1998 • 1,687 citations

Identification and Molecular Characterization of Fractalkine Receptor CX3CR1, which Mediates Both Leukocyte Migration and Adhesion

1997 • 1,406 citations

Change in Coreceptor Use Correlates with Disease Progression in HIV-1–Infected Individuals

1997 • 1,373 citations

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

DISEASES OF THE NERVOUS SYSTEM

1918 • 1,308 citations

Interleukin‐8, a chemotactic and inflammatory cytokine

1992 • 941 citations

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

1997 • 923 citations

Regulation of Rransendothelial Neutrophil Migration by Endogenous Interleukin-8

1991 • 813 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

1993 • 771 citations

Molecular Cloning and Functional Expression of a New Human CC-Chemokine Receptor Gene

1996 • 701 citations

Expression cloning of new receptors used by simian and human immunodeficiency viruses

1997 • 692 citations

Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic mice

1994 • 678 citations

CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

1996 • 669 citations

Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation

1997 • 656 citations

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression

1997 • 642 citations

Leucocyte-endothelial interactions and regulation of leucocyte migration

1994 • 584 citations

A Receptor for the Malarial Parasite Plasmodium vivax : the Erythrocyte Chemokine Receptor

1993 • 583 citations

Astrocyte expression of mRNA encoding cytokines IP‐10 and JE/MCP‐1 in experimental autoimmune encephalomyelitis

1993 • 496 citations

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4

1998 • 419 citations

Chemokine Receptors in Human Endothelial Cells

1998 • 407 citations

Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1 beta and tumor necrosis factor-alpha.

1992 • 402 citations

Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity

1991 • 397 citations

Signal Transduction Due to HIV-1 Envelope Interactions with Chemokine Receptors CXCR4 or CCR5

1997 • 394 citations

Chemokine expression in murine experimental allergic encephalomyelitis

1995 • 363 citations

Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

1997 • 357 citations

CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

1997 • 327 citations

Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13.

1995 • 318 citations

Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3.

1996 • 314 citations

Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses

1997 • 312 citations

MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphoctye differentiation

1997 • 312 citations

Chemokines and HIV–1 second receptors

1996 • 304 citations

The Duffy antigen/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor.

1995 • 299 citations

Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection

1997 • 295 citations

Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes.

1996 • 288 citations

Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis.

1997 • 284 citations

Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis.

1993 • 277 citations

Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection.

1997 • 267 citations

CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

1997 • 264 citations

Neuronal apoptosis in HIV infection in adults

1995 • 244 citations

Upregulation of Interleukin 8 by Oxygen-deprived Cells in Glioblastoma Suggests a Role in Leukocyte Activation, Chemotaxis, and Angiogenesis

1997 • 244 citations

Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: potential involvement of glial-derived factors

1993 • 244 citations

Identification of CCR8: A Human Monocyte and Thymus Receptor for the CC Chemokine I-309

1997 • 237 citations

CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons.

1997 • 235 citations

The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig

1998 • 235 citations

Interleukin 1 receptors in the brain and endocrine tissues

1993 • 228 citations

Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains

1997 • 223 citations

Monoclonal antibodies detect different distribution patterns of IL-8 receptor A and IL-8 receptor B on human peripheral blood leukocytes.

1994 • 222 citations

Apoptotic neurons in brains from paediatric patients with HIV‐I encephalitis and progressive encephalopathy

1995 • 220 citations

Dynamic regulation of alpha- and beta-chemokine expression in the central nervous system during mouse hepatitis virus-induced demyelinating disease.

1998 • 220 citations

Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis.

1993 • 218 citations

In vitro evaluation of the role of the Duffy blood group in erythrocyte invasion by Plasmodium vivax.

1989 • 212 citations

Shared usage of the chemokine receptor CXCR4 by the feline and human immunodeficiency viruses

1997 • 209 citations

Postcapillary venule endothelial cells in kidney express a multispecific chemokine receptor that is structurally and functionally identical to the erythroid isoform, which is the Duffy blood group antigen.

1994 • 208 citations

gp120-Induced Neurotoxicity in Hippocampal Pyramidal Neuron Cultures: Protective Action of TGF-β1

1996 • 204 citations

In Vivo Distribution of the Human Immunodeficiency Virus/Simian Immunodeficiency Virus Coreceptors: CXCR4, CCR3, and CCR5

1998 • 200 citations

Identification of CCR8, the Receptor for the Human CC Chemokine I-309

1997 • 198 citations

Human immunodeficiency virus envelope glycoprotein/CD4-mediated fusion of nonprimate cells with human cells

1990 • 185 citations

Functional expression of the CXC-chemokine receptor-4/fusin on mouse microglial cells and astrocytes.

1997 • 182 citations

Transplanted human neurons derived from a teratocarcinoma cell line (NTera‐2) mature, integrate, and survive for over 1 year in the nude mouse brain

1995 • 179 citations

Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells.

1995 • 176 citations

Localization of HIV-1 co-receptors CCR5 and CXCR4 in the brain of children with AIDS.

1998 • 175 citations

Monocyte Chemoattractant Protein-3 Is a Functional Ligand for CC Chemokine Receptors 1 and 2B

1995 • 171 citations

Molecular properties of the chemokine receptor family

1994 • 170 citations

The CC Chemokine I-309 Inhibits CCR8-dependent Infection by Diverse HIV-1 Strains

1998 • 169 citations

Cytokine induction of MIP-1 alpha and MIP-1 beta in human fetal microglia.

1998 • 166 citations

Interleukin-4 induces the synthesis and secretion of MCP-1/JE by human endothelial cells.

1991 • 165 citations

Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis.

1996 • 164 citations

Neutrophil infiltration, glial reaction, and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes.

1996 • 159 citations

Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis.

1998 • 148 citations

Complementation of murine cells for human immunodeficiency virus envelope/CD4-mediated fusion in human/murine heterokaryons

1992 • 147 citations

Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239

1997 • 146 citations

Human astrocytomas and glioblastomas express monocyte chemoattractant protein‐1 (MCP‐1) in vivo and in vitro

1994 • 144 citations

Role of the β-Chemokine Receptors CCR3 and CCR5 in Human Immunodeficiency Virus Type 1 Infection of Monocytes and Microglia

1998 • 143 citations

CD4-Independent Infection by HIV-2 (ROD/B): Use of the 7-Transmembrane Receptors CXCR-4, CCR-3, and V28 for Entry

1997 • 140 citations

Regulation of monocyte chemoattractant protein-1 expression in adult human non-neoplastic astrocytes is sensitive to tumor necrosis factor (TNF) or antibody to the 55-kDa TNF receptor

1994 • 136 citations

Phenotypic characterization of CD4+ T cells that exhibit a transendothelial migratory capacity.

1995 • 129 citations

Chemokine Receptor CXCR4 Expression in Endothelium

1998 • 127 citations

Interleukin-8 receptor B immunoreactivity in brain and neuritic plaques of Alzheimer's disease.

1997 • 127 citations

Chemokine Receptor Utilization by Human Immunodeficiency Virus Type 1 Isolates That Replicate in Microglia

1998 • 124 citations

In situ hybridization analysis of glial fibrillary acidic protein mRNA reveals evidence of biphasic astrocyte activation during acute experimental autoimmune encephalomyelitis.

1996 • 124 citations

Identification of cell types producing RANTES, MIP-1α and MIP-1β in rat experimental autoimmune encephalomyelitis by in situ hybridization

1997 • 121 citations

Expression and localization of messenger RNA and protein for monocyte chemoattractant protein-1 in human malignant glioma

1994 • 100 citations

Experimental HIV Infection of Human Lymphoid Tissue: Correlation of CD4⁺T Cell Depletion and Virus Syncytium-Inducing/Non-Syncytium-Inducing Phenotype in Histocultures Inoculated with Laboratory Strains and Patient Isolates of HIV Type 1

1997 • 94 citations

Expression Directed from HIV Long Terminal Repeats in the Central Nervous System of Transgenic Mice

1992 • 89 citations

Identification of the Chemokine Receptor TER1/CCR8 Expressed in Brain-Derived Cells and T Cells as a New Coreceptor for HIV-1 Infection

1998 • 89 citations

I-309/T cell activation gene-3 chemokine protects murine T cell lymphomas against dexamethasone-induced apoptosis.

1996 • 88 citations

The expression of monocyte chemotactic protein (MCP-1) in human vascular endotheliumin vitro andin vivo

1993 • 87 citations

Primary sensory neurons migrate in response to the chemokine RANTES

1998 • 84 citations

Chemokine and matrix metalloproteinase secretion by myelin proteolipid protein-specific CD8+ T cells: potential roles in inflammation.

1997 • 82 citations

Macroglia: neural cells responsive to lymphokines and growth factors

1987 • 80 citations

Induction of RANTES expression by astrocytes and astrocytoma cell lines

1996 • 75 citations

Neural Transplantation as an Experimental Treatment Modality for Cerebral Ischemia

1997 • 69 citations

HIV-1 gp120 Produces DNA Fragmentation in the Cerebral Cortex of Rat

1995 • 67 citations

CD8+ Myelin Peptide-Specific T Cells Can Chemoattract CD4+ Myelin Peptide-Specific T Cells: Importance of IFN-Inducible Protein 10

1998 • 63 citations

HIV-1 induction of CD40 on endothelial cells promotes the outgrowth of AIDS-associated B-cell lymphomas

1997 • 61 citations

IL-1 activation of endothelium supports VLA-4 (CD49d/CD29)-mediated monocyte transendothelial migration to C5a, MIP-1α, RANTES, and PAF but inhibits migration to MCP-1: a regulatory role for endothelium-derived MCP-1

1995 • 55 citations

Identification of an epitope derived from human proteolipid protein that can induce autoreactive CD8+ cytotoxic T lymphocytes restricted by HLA-A3: evidence for cross-reactivity with an environmental microorganism

1997 • 52 citations

Modulation of Feline Immunodeficiency Virus Infection by Stromal Cell-Derived Factor

1998 • 52 citations

The HIV-1 envelope protein GP120 induces neuronal apoptosis in hippocampal slices

1996 • 41 citations

AIDS dementia and HIV-1-induced neurotoxicity: Possible pathogenic associations and mechanisms

1996 • 36 citations

Differentiation of human embryonal carcinoma cells induces human immunodeficiency virus permissiveness which is stimulated by human cytomegalovirus coinfection

1991 • 31 citations

Neuronal expression of human immunodeficiency virus type 1 env proteins in transgenic mice: distribution in the central nervous system and pathological alterations

1995 • 24 citations

Thrombin induces production in human umbilical vein endothelial cells

1995 • 24 citations