Vascular developmental biology: getting nervous

Mechanisms of angiogenesis

1997 • 5,696 citations

Mechanisms of angiogenesis and arteriogenesis

2000 • 4,120 citations

Vascular endothelial growth factor (VEGF) and its receptors

1999 • 3,498 citations

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

1998 • 2,440 citations

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

1996 • 1,951 citations

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

1998 • 1,663 citations

Notch Signaling

1995 • 1,282 citations

Blood Vessel Formation: What Is Its Molecular Basis?

1996 • 1,242 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms.

1992 • 1,145 citations

Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III

1997 • 1,131 citations

Notch signaling is essential for vascular morphogenesis in mice

2000 • 1,042 citations

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

1999 • 1,019 citations

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

1999 • 919 citations

Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis

1996 • 851 citations

A requirement for neuropilin-1 in embryonic vessel formation

1999 • 830 citations

Plexin-Neuropilin-1 Complexes Form Functional Semaphorin-3A Receptors

1999 • 803 citations

Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, Angiopoietins, and ephrins in vascular development

1999 • 795 citations

Embryonic Lethality and Vascular Defects in Mice Lacking the Notch Ligand Jagged1

1999 • 756 citations

Symmetrical Mutant Phenotypes of the Receptor EphB4 and Its Specific Transmembrane Ligand ephrin-B2 in Cardiovascular Development

1999 • 708 citations

Specificities of heparan sulphate proteoglycans in developmental processes

2000 • 706 citations

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

1999 • 681 citations

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

2000 • 556 citations

Vascular Endothelial Growth Factor: Molecular and Biological Aspects

1999 • 542 citations

Dll4, a novel Notch ligand expressed in arterial endothelium

2000 • 522 citations

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

1996 • 497 citations

Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice

1997 • 488 citations

Neuropilin-1 Mediates Collapsin-1/Semaphorin III Inhibition of Endothelial Cell Motility

1999 • 469 citations

Mice lacking both presenilin genes exhibitearlyembryonic patterningdefects

1999 • 462 citations

Semaphorins and their receptors in vertebrates and invertebrates

2000 • 456 citations

In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins

1999 • 431 citations

gridlock , an HLH Gene Required for Assembly of the Aorta in Zebrafish

2000 • 427 citations

Two distinct endothelial lineages in ontogeny, one of them related to hemopoiesis

1996 • 426 citations

Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs

1995 • 412 citations

Neuropilin-2 and Neuropilin-1 Are Receptors for the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF) and of Placenta Growth Factor-2, but Only Neuropilin-2 Functions as a Receptor for the 145-Amino Acid Form of VEGF

2000 • 411 citations

Notch signalling and the control of cell fate choices in vertebrates

1998 • 410 citations

EphrinB Ligands Recruit GRIP Family PDZ Adaptor Proteins into Raft Membrane Microdomains

1999 • 345 citations

Neuropilin-1 Is a Placenta Growth Factor-2 Receptor

1998 • 344 citations

Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation

1998 • 328 citations

gridlock, a localized heritable vascular patterning defect in the zebrafish

1995 • 323 citations

Differential Binding of Vascular Endothelial Growth Factor B Splice and Proteolytic Isoforms to Neuropilin-1

1999 • 304 citations

Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor:In vivoexpression and antitumor activity

2000 • 299 citations

The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation

1997 • 290 citations

HRT1, HRT2, and HRT3: A New Subclass of bHLH Transcription Factors Marking Specific Cardiac, Somitic, and Pharyngeal Arch Segments

1999 • 276 citations

Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos

2000 • 257 citations

Hey genes: a novel subfamily of hairy - and Enhancer of split related genes specifically expressed during mouse embryogenesis

1999 • 249 citations

Flk-1, a Receptor for Vascular Endothelial Growth Factor (VEGF), Is Expressed by Retinal Progenitor Cells

1996 • 239 citations

Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy

2000 • 235 citations

Studies of living nerves. II. Activities of ameboid growth cones, sheath cells, and myelin segments, as revealed by prolonged observation of individual nerve fibers in frog tadpoles

1933 • 231 citations

Eph receptors and ephrins: Regulators of guidance and assembly

2000 • 217 citations

Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alpha vbeta 3 and alpha 5beta 1 integrins

1999 • 202 citations

Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding

1999 • 169 citations

Similarities and differences between the vascular endothelial growth factor (VEGF) splice variants

1996 • 165 citations

A Role for Abl in Notch Signaling

1998 • 161 citations

The basic helix-loop-helix transcription factor, dHAND, is required for vascular development

2000 • 160 citations

Cardiovascular Basic Helix Loop Helix Factor 1, a Novel Transcriptional Repressor Expressed Preferentially in the Developing and Adult Cardiovascular System

2000 • 155 citations

Signaling by Eph receptors and their ephrin ligands

1998 • 147 citations

Autonomous and non-autonomous regulation of mammalian neurite development by Notch1 and Delta1

1999 • 143 citations

Expression of Eph receptors and ephrins is differentially regulated by E-cadherin

2000 • 119 citations

Vascular development and disorders: Molecular analysis and pathogenic insights

1998 • 110 citations

What guides early embryonic blood vessel formation?

1999 • 108 citations

AL‐1‐induced Growth Cone Collapse of Rat Cortical Neurons is Correlated with REK7 Expression and Rearrangement of the Actin Cytoskeleton

1997 • 103 citations

Specifying the path of the intersegmental nerve of the Drosophila embryo: a role for Delta and Notch

1993 • 88 citations

Ephrin-A1 is expressed at sites of vascular development in the mouse

1998 • 88 citations

Origins of the neurovascular bundle: interactions between developing nerves and blood vessels in embryonic chick skin.

1989 • 65 citations

Lack of requirement for Presenilin1 in Notch1 signaling

1999 • 42 citations

Extrinsic and Intrinsic Cholinergic Systems of the Vascular Wall

1999 • 20 citations

Deleted Work

1955 • 0 citations