Flk-1, a Receptor for Vascular Endothelial Growth Factor (VEGF), Is Expressed by Retinal Progenitor Cells

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Sonic hedgehog mediates the polarizing activity of the ZPA

1993 • 2,313 citations

Production of high-titer helper-free retroviruses by transient transfection.

1993 • 2,280 citations

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

1989 • 2,267 citations

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1990 • 2,129 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Growth factor signaling by receptor tyrosine kinases

1992 • 1,450 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

A common progenitor for neurons and glia persists in rat retina late in development

1987 • 1,395 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

Notch Signaling

1995 • 1,282 citations

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1994 • 1,249 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

SIGNALLING BY RECEPTOR TYROSINE KINASES

1993 • 1,098 citations

Cell differentiation in the retina of the mouse

1985 • 1,041 citations

Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia

1995 • 990 citations

Cell fate determination in the vertebrate retina.

1996 • 976 citations

In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

1995 • 849 citations

Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

1994 • 801 citations

Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

1995 • 740 citations

Cell Cycle Dependence of Laminar Determination in Developing Neocortex

1991 • 718 citations

flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors

1993 • 707 citations

Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta

1995 • 669 citations

Widespread Dispersion of Neuronal Clones Across Functional Regions of the Cerebral Cortex

1992 • 610 citations

Cell lineage analysis reveals multipotency of some avian neural crest cells

1988 • 585 citations

A self-renewing multipotential stem cell in embryonic rat cerebral cortex

1994 • 578 citations

Fibroblast growth factors induce additional limb development from the flank of chick embryos

1995 • 578 citations

Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells.

1989 • 568 citations

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.

1991 • 516 citations

Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis

1995 • 476 citations

Spatial and Temporal Patterns of Neurogenesis in the Chick Retina

1991 • 435 citations

Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch

1995 • 409 citations

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases

1994 • 332 citations

Cell cycle dependence of laminar determination in developing neocortex

1991 • 327 citations

Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons

1995 • 307 citations

The Vascular System of the Cerebral Cortex

1980 • 306 citations

Platelet endothelial cell adhesion molecule-1 (PECAM-1 / CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development

1994 • 301 citations

Rod photoreceptor development in vitro: Intrinsic properties of proliferating neuroepithelial cells change as development proceeds in the rat retina

1990 • 299 citations

Xotch inhibits cell differentiation in the xenopus retina

1995 • 293 citations

Cytogenesis in the monkey retina

1991 • 285 citations

Control of proliferation in the retina: temporal changes in responsiveness to FGF and TGFα

1992 • 276 citations

Lineage, arrangement, and death of clonally related motoneurons in chick spinal cord

1990 • 249 citations

Changes in retinal cell fate induced by overexpression of EGF receptor

1995 • 248 citations

Regeneration of neural retina from the pigmented epithelium in the chick embryo

1965 • 242 citations

Signaling by Receptor Tyrosine Kinases

1993 • 242 citations

Development of the pattern of photoreceptors in the chick retina

1996 • 213 citations

Lineage of radial glia in the chicken optic tectum

1992 • 187 citations

Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps

1995 • 187 citations

Evidence for multiple precursor cell types in the embryonic rat cerebral cortex

1995 • 182 citations

A temporally regulated, diffusible activity is required for rod photoreceptor development in vitro

1992 • 180 citations

The neurotrophins and their receptors

1993 • 173 citations

Introduction

1980 • 163 citations

Receptor tyrosine kinases: genetic evidence for their role in Drosophila and mouse development

1990 • 161 citations

bFGF, neurotrophins, and the control of cortical neurogenesis

1995 • 161 citations

Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain

1994 • 135 citations

eph, the largest known family of putative growth factor receptors

1994 • 112 citations

The Torso Pathway in Drosophila: Lessons on Receptor Tyrosine Kinase Signaling and Pattern Formation

1994 • 109 citations

Cell cycle dependence of laminar determination in developing neocortex

1992 • 108 citations

Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila

1994 • 102 citations

Self-renewal of stem cells and differentiation of nerve cells in the developing chick retina

1983 • 90 citations

Clones in the chick diencephalon contain multiple cell types and siblings are widely dispersed

1996 • 78 citations

Signal transduction during C. elegans vulval induction

1991 • 75 citations

Mitogenic response to colony-stimulating factor 1

1991 • 62 citations

A perfect vulva every time: Gradients and signaling cascades in C. elegans

1995 • 58 citations

Molecular cloning of the murine JAK1 protein tyrosine kinase and its expression in the mouse central nervous system

1993 • 40 citations

Roles of receptor tyrosine kinases in Drosophila development

1992 • 37 citations

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases

1995 • 35 citations

Control of photoreceptor development

1992 • 17 citations

Induction of the R7 Neuron in the Drosophila Compound Eye: The bride of sevenless and sevenless Interaction

1992 • 6 citations

Deleted Work

1955 • 0 citations