Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathway.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

A simplified method for cyanogen bromide activation of agarose for affinity chromatography

1974 • 1,951 citations

Carbohydrate-Specific Receptors of the Liver

1982 • 1,895 citations

Endocytosis and the recycling of plasma membrane.

1983 • 1,447 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1983 • 780 citations

Radioiodination of proteins in single polyacrylamide gel slices. Tryptic peptide analysis of all the major members of complex multicomponent systems using microgram quantities of total protein.

1977 • 778 citations

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

1984 • 656 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

1979 • 517 citations

The galactose-specific recognition system of mammalian liver: The route of ligand internalization in rat hepatocytes

1980 • 484 citations

Low temperature selectively inhibits fusion between pinocytic vesicles and lysosomes during heterophagy of 125I-asialofetuin by the perfused rat liver.

1980 • 451 citations

Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts.

1984 • 357 citations

Ultrastructural localization of several phosphatases with cerium.

1983 • 338 citations

Nerve growth factor receptors on PC12 cells: Evidence for two receptor classes with differing cytoskeletal association

1981 • 302 citations

Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes.

1984 • 295 citations

The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae

1984 • 291 citations

Molecular mechanism of mitogen action: Processing of receptor induced by epidermal growth factor

1978 • 271 citations

Studies on a mammalian hepatic binding protein specific for asialoglycoproteins. Evidence for receptor recycling in isolated rat hepatocytes.

1980 • 270 citations

Receptor-mediated endocytosis of epidermal growth factor by hepatocytes in the perfused rat liver: ligand and receptor dynamics.

1984 • 265 citations

Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654.

1985 • 244 citations

Glycosylation of the epidermal growth factor receptor in A-431 cells. The contribution of carbohydrate to receptor function.

1984 • 229 citations

Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

1984 • 219 citations

The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts.

1983 • 196 citations

Assessment of protein turnover in perfused rat liver. Evidence for amino acid compartmentation from differential labeling of free and tRNA-gound valine.

1976 • 192 citations

Immunoaffinity purification of the epidermal growth factor receptor. Stoichiometry of binding and kinetics of self-phosphorylation.

1984 • 186 citations

Synthesis, turnover, and down-regulation of epidermal growth factor receptors in human A431 epidermoid carcinoma cells and skin fibroblasts.

1982 • 185 citations

Purification and characterization of epidermal growth factor receptor/protein kinase from normal mouse liver.

1982 • 183 citations

Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment.

1984 • 176 citations

Intracellular dissociation of receptor-bound asialoglycoproteins in cultured hepatocytes. A pH-mediated nonlysosomal event.

1983 • 176 citations

Uptake of Insulin and Other Ligands into Receptor-Rich Endocytic Components of Target Cells: The Endosomal Apparatus

1985 • 163 citations

Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line.

1983 • 155 citations

Internalized insulin receptors are recycled to the cell surface in rat hepatocytes.

1982 • 142 citations

Identification of rat hepatocyte plasma membrane proteins using monoclonal antibodies.

1985 • 140 citations

Receptor-mediated biliary transport of immunoglobulin A and asialoglycoprotein: sorting and missorting of ligands revealed by two radiolabeling methods.

1984 • 122 citations

Post-translational processing of the epidermal growth factor receptor. Glycosylation-dependent acquisition of ligand-binding capacity.

1985 • 119 citations

Degradation of the acetylcholine receptor in cultured muscle cells: Selective inhibitors and the fate of undegraded receptors

1980 • 111 citations

A domain-specific marker for the hepatocyte plasma membrane: localization of leucine aminopeptidase to the bile canalicular domain.

1983 • 111 citations

Inhibition of 125I-asialofetuin catabolism by leupeptin in the perfused rat liver and in vivo.

1979 • 105 citations

Evidence for different pathways for the degradation of insulin and insulin receptor in the chick liver cell.

1982 • 93 citations

Endogenous and exogenous domain markers of the rat hepatocyte plasma membrane.

1985 • 92 citations

Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin.

1984 • 89 citations

Cytochemical localization of acid phosphatase and trimetaphosphatase activities in exocrine acinar cells.

1980 • 80 citations

125I-wheat germ agglutinin blotting: Increased sensitivity with polyvinylpyrrolidone quenching and periodate oxidation/reductive phenylamination

1984 • 71 citations

Conformational changes in the receptors for epidermal growth factor and asialoglycoproteins induced by the mildly acidic pH found in endocytic vesicles.

1984 • 67 citations

Properties of the nerve growth factor receptor. Relationship between receptor structure and affinity.

1985 • 66 citations

Insulin receptor regulation and desensitization in rat hepatoma cells. The loss of the oligomeric forms of the receptor correlates with the change in receptor affinity.

1984 • 62 citations

Solubilization of EGF receptor with Triton X-100 alters stimulation of tyrosine residue phosphorylation by EGF and dimethyl sulfoxide.

1983 • 42 citations

[18] Use of isolated, perfused liver in studies of receptor-mediated endocytosis

1983 • 39 citations

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