Properties of the nerve growth factor receptor. Relationship between receptor structure and affinity.

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

The Nerve Growth Factor: Biochemistry, Synthesis, and Mechanism of Action

1980 • 733 citations

Characterization and isolation of proteolytically modified nerve growth factor

1976 • 677 citations

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

1979 • 627 citations

Site-site interactions among insulin receptors. Characterization of the negative cooperativity.

1976 • 601 citations

Rapid isolation of plasma membranes in high yield from cultured fibroblasts

1977 • 304 citations

Nerve growth factor receptors on PC12 cells: Evidence for two receptor classes with differing cytoskeletal association

1981 • 302 citations

Nerve Growth Factor and Insulin

1972 • 283 citations

Purification of insulin receptor with full binding activity.

1983 • 273 citations

Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states.

1980 • 255 citations

Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin

1978 • 223 citations

Properties of the Specific Binding of 125I-Nerve Growth Factor to Responsive Peripheral Neurons

1974 • 199 citations

Binding of insuling and other hormones to non-receptor materials: Saturability, specificity and apparent “negative cooperativity”

1975 • 197 citations

Cooperative properties of hormone receptors in cell membranes

1976 • 170 citations

Purification of the receptor for nerve growth factor from A875 melanoma cells by affinity chromatography.

1983 • 104 citations

Affinity labeling and partial purification of nerve growth factor receptors from rat pheochromocytoma and human melanoma cells.

1983 • 99 citations

Alteration of binding properties and cytoskeletal attachment of nerve growth factor receptors in PC12 cells by wheat germ agglutinin.

1982 • 98 citations

Properties and Specificity of Binding Sites for 125I-Nerve Growth Factor in Embryonic Heart and Brain

1974 • 98 citations

Insulin receptors convert to a higher affinity state subsequent to hormone binding. A two-state model for the insulin receptor.

1982 • 89 citations

The insulin receptor: structural features

1981 • 65 citations

Formation of a receptor state from which insulin dissociates slowly in hepatic cells and plasma membranes.

1980 • 62 citations

Change in state of nerve growth factor receptor. Modulation of receptor affinity by wheat germ agglutinin.

1983 • 53 citations

Dissociation kinetics of 125I-nerve growth factor from cell surface receptors. Acceleration by unlabeled ligand and its relationship to negative cooperativity.

1981 • 50 citations

A comparison of binding properties and structure of NGF receptor on PC12 pheochromocytoma and A875 melanoma cells

1983 • 48 citations

Hormone-induced conformational changes in the hepatic insulin receptor.

1983 • 46 citations

The Nerve Growth Factor Receptor on PC 12 Cells: Interconversion Between Two Forms with Different Binding Properties

1983 • 35 citations