Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin.

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Coated pits, coated vesicles, and receptor-mediated endocytosis

1979 • 2,073 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1983 • 780 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

Binding of apotransferrin to K562 cells: explanation of the transferrin cycle.

1983 • 603 citations

Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses*

1981 • 596 citations

Receptor-mediated endocytosis of transferrin in K562 cells.

1983 • 576 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431.

1979 • 528 citations

Receptor-mediated endocytosis of transferrin and the uptake of fe in K562 cells: identification of a nonlysosomal acidic compartment.

1982 • 486 citations

[45] The use of intensifying screens or organic scintillators for visualizing radioactive molecules resolved by gel electrophoresis

1980 • 367 citations

Two species of lysosomal organelles in cultured human fibroblasts

1979 • 360 citations

Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts.

1984 • 357 citations

Insulin-induced receptor loss in cultured human lymphocytes is due to accelerated receptor degradation.

1981 • 217 citations

[46] Enzymic diagnosis of the genetic mucopolysaccharide storage disorders

1978 • 204 citations

The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts.

1983 • 196 citations

Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis.

1983 • 195 citations

Intracellular dissociation of receptor-bound asialoglycoproteins in cultured hepatocytes. A pH-mediated nonlysosomal event.

1983 • 176 citations

Degradation of receptor-bound human choriogonadotropin by murine Leydig tumor cells.

1978 • 165 citations

Monensin inhibits intracellular dissociation of asialoglycoproteins from their receptor.

1983 • 157 citations

Internalization and degradation of receptor-bound human choriogonadotropin in Leydig tumor cells. Fate of the hormone subunits.

1982 • 155 citations

Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line.

1983 • 155 citations

Defective acidification of endosomes in Chinese hamster ovary cell mutants "cross-resistant" to toxins and viruses.

1983 • 153 citations

On the mechanisms involved in the regulation of the cell-surface receptors for human choriogonadotropin and mouse epidermal growth factor in cultured Leydig tumor cells.

1983 • 106 citations

Inhibition of the degradation of receptor-bound human choriogonadotropin by lysosomotropic agents, protease inhibitors, and metabolic inhibitors

1978 • 87 citations

Removal of the surface-bound human choriogonadotropin results in the cessation of hormonal responses in cultured Leydig tumor cells.

1981 • 80 citations

Desensitization to gonadotropins in cultured Leydig tumor cells involves loss of gonadotropin receptors and decreased capacity for steroidogenesis.

1981 • 73 citations

Evidence that human platelet alpha-adrenergic receptors coupled to inhibition of adenylate cyclase are not associated with the subunit of adenylate cyclase ADP-ribosylated by cholera toxin.

1982 • 61 citations

Lysosomal Cathepsin B1: Partial Characterization in Rat Preputial Gland and Recompartmentation in Response to Estradiol‐17β

1976 • 58 citations

An Improved Method for the Solubilization of Stable Gonadotropin Receptors*

1983 • 44 citations

Inhibition of the degradation of receptor-bound human choriogonadotropin by leupeptin

1979 • 24 citations