Internalized insulin receptors are recycled to the cell surface in rat hepatocytes.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Insulin-Dependent Regulation of Insulin Receptor Concentrations: A Direct Demonstration in Cell Culture

1974 • 1,037 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells.

1978 • 678 citations

Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts

1981 • 593 citations

Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: Characterization and evidence for receptor recycling

1980 • 574 citations

The Relationship between the Insulin-binding Capacity of Fat Cells and the Cellular Response to Insulin

1971 • 464 citations

Interaction of cross-linking agents with the insulin effector system of isolated fat cells. Covalent linkage of 125I-insulin to a plasma membrane receptor protein of 140,000 daltons.

1979 • 422 citations

A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts

1977 • 280 citations

Studies on a mammalian hepatic binding protein specific for asialoglycoproteins. Evidence for receptor recycling in isolated rat hepatocytes.

1980 • 270 citations

Insulin-induced receptor loss in cultured human lymphocytes is due to accelerated receptor degradation.

1981 • 217 citations

Photoaffinity labeling of insulin receptor of rat adiopocyte plasma membrane.

1978 • 216 citations

Primary amines inhibit recycling of α2M receptors in fibroblasts

1980 • 213 citations

Characterization of the low density lipoprotein receptor in membranes prepared from human fibroblasts.

1978 • 211 citations

Internalization of polypeptide hormones

1980 • 207 citations

On the mechanism of ligand-induced down-regulation of insulin receptor level in the liver cell.

1981 • 198 citations

Polypeptide-Binding Membrane Receptors: Analysis and Classification

1981 • 195 citations

Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes.

1981 • 188 citations

Down Regulation of Insulin Receptors in Primary Cultures of Adult Rat Hepatocytes in Monolayer*

1978 • 178 citations

Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography.

1979 • 174 citations

Insulin Today

1977 • 172 citations

125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography.

1978 • 171 citations

Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level.

1980 • 168 citations

Insulin and glucagon stimulation of amino acid transport in isolated rat hepatocytes. Synthesis of a high affinity component of transport.

1979 • 155 citations

Insulin-induced loss of the insulin receptor in IM-9 lymphocytes. A biological process mediated through the insulin receptor.

1980 • 149 citations

Fate of plasma membrane during endocytosis. II. Evidence for recycling (shuttle) of plasma membrane constituents

1979 • 145 citations

Acetylcholine receptor degradation measured by density labeling: Effects of cholinergic ligands and evidence against recycling

1979 • 125 citations

Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes.

1982 • 102 citations

Evidence for reutilization of surface receptors for α-macroglobulin · protease complexes in rabbit alveolar macrophages

1980 • 100 citations

Solubilization of the low density lipoprotein receptor

1979 • 87 citations

Regulation of insulin receptors: evidence for involvement of an endocytotic internalization pathway.

1980 • 72 citations

Hormone Binding Alters the Conformation of the Insulin Receptor

1980 • 70 citations

Autoantibodies Against the Insulin Receptor Recognize the Insulin Binding Subunits of an Oligomeric Receptor

1981 • 64 citations

Insulin-induced receptor loss in the cultured human lymphocyte: quantitative morphological perturbations in the cell and plasma membrane

1979 • 39 citations

Accumulation of epidermal growth factor within cells does not depend on receptor recycling

1980 • 36 citations

The Fate of [¹²⁵I]Iodoepidermal Growth Factor in Isolated Hepatocytes: A Quantitative Electron Microscopic Autoradiographic Study*

1981 • 35 citations