Myeloid haemopoietic growth factors

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Van Damme A.

1986 • 3,477 citations

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1966 • 1,944 citations

The Human Hematopoietic Colony-Stimulating Factors

1987 • 1,728 citations

The Cell Biology of Macrophage Activation

1984 • 1,623 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

1986 • 1,260 citations

There is more than one interleukin 1

1986 • 1,226 citations

The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression

1987 • 1,180 citations

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1988 • 1,086 citations

The Granulocyte-Macrophage Colony-Stimulating Factors

1985 • 1,007 citations

Growth of factor-dependent hemopoietic precursor cell lines.

1980 • 793 citations

Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Hematopoietic Reconstitution after High-Dose Chemotherapy and Autologous Bone Marrow Transplantation

1988 • 779 citations

Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells.

1977 • 740 citations

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

1986 • 733 citations

IL3-dependent mouse clones that express B-220 surface antigen, contain ig genes in germ-line configuration, and generate B lymphocytes in vivo

1985 • 718 citations

Granulocyte- and granulocyte– macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate

1989 • 652 citations

Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment

1987 • 636 citations

Effect of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor on Myelopoiesis in the Acquired Immunodeficiency Syndrome

1987 • 633 citations

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor.

1988 • 619 citations

Interleukin 1: An Immunological Perspective

1985 • 576 citations

Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator

1985 • 566 citations

The Hemopoietic Colony-stimulating Factors

1995 • 565 citations

Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells.

1988 • 565 citations

Molecular Cloning of a Complementary DNA Encoding Human Macrophage-Specific Colony-Stimulating Factor (CSF-1)

1985 • 542 citations

CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factor

1983 • 536 citations

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors.

1988 • 528 citations

Recombinant human TNF induces production of granulocyte–monocyte colony-stimulating factor

1986 • 528 citations

Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells.

1987 • 523 citations

Apparent role of the macrophage growth factor, CSF-1, in placental development

1987 • 506 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus

1986 • 478 citations

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

1984 • 451 citations

Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates.

1987 • 428 citations

Induction of Macrophage Tumoricidal Activity by Granulocyte-Macrophage Colony-Stimulating Factor

1986 • 418 citations

Adherence induces selective mRNA expression of monocyte mediators and proto-oncogenes.

1988 • 411 citations

Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts.

1987 • 408 citations

Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II

1986 • 405 citations

Stimulation of haematopoiesis in primates by continuous infusion of recombinant human GM-CSF

1986 • 405 citations

Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor, and colony stimulating activity.

1986 • 397 citations

Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage

1987 • 384 citations

Human CSF-1: Molecular Cloning and Expression of 4-kb cDNA Encoding the Human Urinary Protein

1987 • 381 citations

Transient nature of early haematopoietic spleen colonies

1982 • 377 citations

Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation

1987 • 377 citations

Human Recombinant Granulocyte-Macrophage Colony-Stimulating Factor: A Multilineage Hematopoietin

1985 • 374 citations

The induction of clones of normal mast cells by a substance from conditioned medium

1966 • 358 citations

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor)

1987 • 357 citations

Cell Surface Receptors: A Short Course on Theory and Methods

1996 • 351 citations

Human IL-3 and GM-CSF Act Synergistically in Stimulating Hematopoiesis in Primates

1988 • 333 citations

Human GM-CSF primes neutrophils for enhanced oxidative metabolism in response to the major physiological chemoattractants

1987 • 333 citations

Synergism between interleukin-6 and interleukin-3 in supporting proliferation of human hematopoietic stem cells: comparison with interleukin-1 alpha

1988 • 331 citations

Molecular mechanisms of signal transduction in macrophages

1987 • 331 citations

Granulocyte-macrophage colony-stimulating factor enhances phagocytosis of bacteria by human neutrophils

1986 • 331 citations

Hierarchical down-modulation of hemopoietic growth factor receptors

1985 • 314 citations

Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice

1986 • 313 citations

Enhancement of human eosinophil cytotoxicity and leukotriene synthesis by biosynthetic (recombinant) granulocyte-macrophage colony-stimulating factor.

1986 • 297 citations

Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3, and functional properties of eosinophils produced in cultures.

1985 • 296 citations

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

1986 • 288 citations

Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes.

1986 • 284 citations

Hemopoietic responses in mice injected with purified recombinant murine GM-CSF.

1987 • 284 citations

Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1

1986 • 283 citations

Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF

1988 • 277 citations

Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factors

1986 • 269 citations

Interdependence of the radioprotective effects of human recombinant interleukin 1 alpha, tumor necrosis factor alpha, granulocyte colony-stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor.

1988 • 265 citations

Control of hemopoiesis by a bone marrow stromal cell clone: lipopolysaccharide- and interleukin-1-inducible production of colony- stimulating factors

1987 • 263 citations

Limitation of Excessive Myelopoiesis by the Intrinsic Modulation of Macrophage-Derived Prostaglandin E

1978 • 263 citations

Interleukin 1 stimulates human endothelial cells to produce granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor.

1987 • 259 citations

Regulation of T cell differentiation: in vitro induction of 20 alpha-hydroxysteroid dehydrogenase in splenic lymphocytes from athymic mice by a unique lymphokine.

1981 • 252 citations

Interleukin 1 induces human marrow stromal cells in long-term culture to produce granulocyte colony-stimulating factor and macrophage colony- stimulating factor

1988 • 248 citations

Activation of antibody-dependent cell-mediated cytotoxicity of human neutrophils and eosinophils by separate colony-stimulating factors.

1983 • 248 citations

Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation.

1988 • 247 citations

Cell Surface Receptors: A Short Course on Theory and Methods

1986 • 246 citations

Hemopoietic Growth Factors: A Review

1992 • 239 citations

Additive effects of interleukin 1 and tumour necrosis factor-alpha on the accumulation of the three granulocyte and macrophage colony-stimulating factor mRNAs in human endothelial cells.

1987 • 238 citations

Expression of the M-CSF (CSF-1) gene by human monocytes

1987 • 238 citations

Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells

1985 • 233 citations

The chromosomal gene structure and two mRNAs for human granulocyte colony-stimulating factor.

1986 • 227 citations

Stimulation by Granulocyte-Macrophage Colony-Stimulating Factor of Leishmania Tropica Killing by Macrophages

1979 • 227 citations

Stimulation of macrophage plasminogen activator activity by colony‐stimulating factors

1980 • 223 citations

Proliferative effects of purified granulocyte colony‐stimulating factor (G‐CSF) on normal mouse hemopoietic cells

1983 • 221 citations

Human granulocyte-monocyte colony-stimulating factor and interleukin 3 stimulate monocyte cytotoxicity through a tumor necrosis factor- dependent mechanism

1988 • 221 citations

Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: comparison with recombinant human granulocyte-macrophage colony-stimulating factor

1987 • 216 citations

Binding of125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic cells

1985 • 215 citations

Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma.

1987 • 215 citations

Effects of B cell stimulatory factor-1/interleukin 4 on hematopoietic progenitor cells

1987 • 213 citations

Interleukin-3 supports growth of mouse pre-B-cell clones in vitro

1984 • 213 citations

Production of Colony-Stimulating Factor in Mitogen-Stimulated Lymphocyte Cultures

1974 • 213 citations

Recombinant human TNF alpha stimulates production of granulocyte colony- stimulating factor

1987 • 212 citations

Interleukin 1 induces cultured human endothelial cell production of granulocyte-macrophage colony-stimulating factor.

1987 • 212 citations

Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5

1987 • 209 citations

Long-term in vitro culture of murine mast cells. I. Description of a growth factor-dependent culture technique.

1981 • 208 citations

Recombinant human granulocyte colony-stimulating factor enhances superoxide release in human granulocytes stimulated by the chemotactic peptide

1987 • 207 citations

Molecules stimulating early red cell, granulocyte, macrophage, and megakaryocyte precursors in culture: Similarity in size, hydrophobicity, and charge

1982 • 207 citations

The interaction of 125I-colony-stimulating factor-1 with bone marrow-derived macrophages.

1986 • 205 citations

Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays.

1983 • 204 citations

Biosynthetic (recombinant) human granulocyte-macrophage colony- stimulating factor: effect on normal bone marrow and leukemia cell lines

1986 • 203 citations

Characterization of the human granulocyte-macrophage colony-stimulating factor receptor.

1988 • 202 citations

Recombinant human granulocyte/macrophage colony-stimulating factor activates intracellular killing of Leishmania donovani by human monocyte-derived macrophages.

1987 • 194 citations

Regulation of cytolytic T-lymphocyte generation by B-cell stimulatory factor

1987 • 193 citations

Activation of granulocyte cytotoxic function by purified mouse colony-stimulating factors.

1983 • 193 citations

Characterization and partial purification of a haemopoietic cell growth factor in WEHI-3 cell conditioned medium

1983 • 192 citations

Recombinant human TNF alpha stimulates production of granulocyte colony- stimulating factor

1987 • 189 citations

Direct stimulation by purified GM-CSF of the proliferation of multipotential and erythroid precursor cells

1980 • 188 citations

Leukotriene production in human neutrophils primed by recombinant human granulocyte/macrophage colony-stimulating factor and stimulated with the complement component C5A and FMLP as second signals.

1988 • 185 citations

Recombinant human interleukin 5 is an eosinophil differentiation factor but has no activity in standard human B cell growth factor assays

1987 • 180 citations

Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model.

1987 • 179 citations

Human granulocyte-macrophage colony-stimulating factor induces expression of the tumor necrosis factor gene by the U937 cell line and by normal human monocytes.

1987 • 178 citations

The regulation of mononuclear phagocyte entry into S phase by the colony stimulating factor CSF‐1

1985 • 178 citations

Growth of B-lymphocyte colonies in vitro.

1975 • 173 citations

Characterization of a serum factor stimulating the differentiation of myelomonocytic leukemic cells

1980 • 170 citations

Murine eosinophil differentiation factor. An eosinophil-specific colony-stimulating factor with activity for human cells.

1986 • 170 citations

Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor

1987 • 169 citations

Granulocyte/macrophage colony-stimulating factor induces interleukin 1 production by human polymorphonuclear neutrophils.

1988 • 165 citations

Recombinant human GM-CSF induces leukocytosis and activates peripheral blood polymorphonuclear neutrophils in nonhuman primates

1987 • 164 citations

Human colony-stimulating factor (CSF-1) radioimmunoassay: resolution of three subclasses of human colony-stimulating factors

1981 • 164 citations

Effects of recombinant human granulocyte and macrophage colony-stimulating factors on signal transduction pathways in human granulocytes.

1987 • 160 citations

Protective effect of human granulocyte colony-stimulating factor on microbial infection in neutropenic mice

1987 • 160 citations

Human recombinant granulocyte-macrophage colony-stimulating factor and interleukin 3 cause basophil histamine release.

1988 • 158 citations

Evidence for specific receptors for interleukin 3 on lymphokine-dependent cell lines established from long-term bone marrow cultures.

1984 • 155 citations

Proliferation of Hemopoietic Colony-Forming Cells Transplanted into Irradiated Mice

1964 • 150 citations

Interleukin 1 stimulates T lymphocytes to produce granulocyte-monocyte colony-stimulating factor.

1988 • 150 citations

Characterization of the cell surface receptor for granulocyte-macrophage colony-stimulating factor.

1986 • 149 citations

In vitro actions on hemopoietic cells of recombinant murine GM‐CSF purified after production in Escherichia coli: Comparison with purified native GM‐CSF

1986 • 149 citations

Why do hemopoietic growth factor receptors interact with each other?

1987 • 148 citations

Epidermal cells synthesize a cytokine with interleukin 3-like properties.

1985 • 145 citations

Characterization of the cell surface receptor for human granulocyte/macrophage colony-stimulating factor.

1986 • 141 citations

Induction of neutrophilic granulocytosis in mice by administration of purified human native granulocyte colony-stimulating factor (G-CSF)

1987 • 141 citations

Recombinant murine granulocyte macrophage colony-stimulating factor has megakaryocyte colony-stimulating activity and augments megakaryocyte colony stimulation by interleukin 3.

1987 • 139 citations

Synergism among interleukin 1, interleukin 3, and interleukin 5 in the production of eosinophils from primitive hemopoietic stem cells.

1988 • 138 citations

Interleukin‐1 regulation of hematopoietic growth factor production by human stromal fibroblasts

1988 • 136 citations

Granulocyte/macrophage-, megakaryocyte-, eosinophil- and erythroid-colony-stimulating factors produced by mouse spleen cells

1980 • 132 citations

Interleukin 3-specific tyrosine phosphorylation of a membrane glycoprotein of Mr 150,000 in multi-factor-dependent myeloid cell lines.

1987 • 129 citations

Purified colony stimulating factors (G‐CSF and GM‐CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity

1987 • 125 citations

Primary human myeloid leukemia cells: comparative responsiveness to proliferative stimulation by GM-CSF or G-CSF and membrane expression of CSF receptors.

1987 • 124 citations

Synthesis by mouse peritoneal cells of G-CSF, the differentiation inducer for myeloid leukemia cells: Stimulation by endotoxin, M-CSF and multi-CSF

1985 • 124 citations

Characterization of the cell surface receptor for a multi-lineage colony-stimulating factor (CSF-2 alpha).

1986 • 122 citations

Recombinant murine GM-CSF from E. coli has biological activity and is neutralized by a specific antiserum.

1985 • 121 citations

Human eosinophil hematopoiesis studied in vitro by means of murine eosinophil differentiation factor (IL5): production of functionally active eosinophils from normal human bone marrow

1988 • 120 citations

Similar molecular properties of granulocyte-macrophage colony-stimulating factors produced by different mouse organs in vitro and in vivo.

1979 • 119 citations

Different colony-stimulating factors are detected by the "interleukin- 3"-dependent cell lines FDC-Pl and 32D cl-23

1984 • 118 citations

Mononuclear phagocytes : characteristics, physiology, and function

1985 • 117 citations

Effect of human recombinant granulocyte colony-stimulating factor on hematopoietic injury in mice induced by 5-fluorouracil

1987 • 114 citations

Identification of distinct receptors for two hemopoietic growth factors (granulocyte colony-stimulating factor and multipotential colony-stimulating factor) by chemical cross-linking.

1986 • 113 citations

The v-fms oncogene induces factor independence and tumorigenicity in CSF-1 dependent macrophage cell line

1986 • 113 citations

Granulocyte/macrophage colony-stimulating factor stimulates monocyte and tissue macrophage proliferation and enhances their responsiveness to macrophage colony-stimulating factor

1988 • 112 citations

Demonstration of burst-promoting activity of recombinant human GM-CSF on circulating erythroid progenitors using an assay involving the delayed addition of erythropoietin

1985 • 112 citations

Establishment of continuous cultures of Thy1.2+, Lytl+,2−T cells with purified interleukin 3

1981 • 112 citations

Stimulation of phagocytosis in bone marrow-derived mouse macrophages by bacterial lipopolysaccharide: correlation with biochemical and functional parameters.

1984 • 111 citations

Interleukin-6 enhances growth factor-dependent proliferation of the blast cells of acute myeloblastic leukemia

1988 • 107 citations

Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice.

1987 • 104 citations

Interleukin 3 promotes the in vitro proliferation of murine pluripotent hematopoietic stem cells.

1985 • 98 citations

Colony-stimulating factors regulate the development of multinucleated osteoclasts from recently replicated cells in vitro.

1987 • 95 citations

Effect of haematopoietic cell growth factor on intracellular ATP levels

1983 • 93 citations

Stimulation of macrophage tumoricidal activity by the growth and differentiation factor CSF-1

1987 • 92 citations

Haemopoietic cell growth factor mediates cell survival via its action on glucose transport.

1984 • 92 citations

Activities of four purified growth factors on highly enriched human hematopoietic progenitor cells

1987 • 91 citations

The haemopoietic growth factors interleukin 3 and colony stimulating factor-1 stimulate proliferation but do not induce inositol lipid breakdown in murine bone-marrow-derived macrophages.

1986 • 90 citations

Blood and Its Disorders

1975 • 88 citations

Effect of Abelson murine leukemia virus on granulocytic differentiation and interleukin-3 dependence of a murine progenitor cell line.

1987 • 88 citations

Activation and proliferation signals in murine macrophages: Stimulation of glucose uptake by hemopoietic growth factors and other agents

1988 • 87 citations

Expression, purification and characterization of recombinant marine granulocyte-macrophage colony-stimulating factor and bovine interleukin-2 from yeast

1987 • 86 citations

Binding of iodinated multipotential colony‐stimulating factor (interleukin‐3) to murine bone marrow cells

1986 • 85 citations

Macrophage colony formation supported by purified CSF-1 and/or interleukin 3 in serum-free culture: evidence for hierarchical difference in macrophage colony-forming cells

1986 • 84 citations

Histamine-producing cell-stimulating activity. Interleukin 3 and granulocyte-macrophage colony-stimulating factor induce de novo synthesis of histidine decarboxylase in hemopoietic progenitor cells.

1987 • 83 citations

Granulocyte-macrophage colony-stimulating factor modulates the excitation-response coupling sequence in human neutrophils.

1988 • 82 citations

Activation and proliferation signals in murine macrophages: Stimulation of Na⁺, K⁺‐ATPase activity by hemopoietic growth factors and other agents

1988 • 82 citations

CSF-1-induced resistance to viral infection in murine macrophages.

1987 • 81 citations

Effect of colony stimulating factor on murine macrophages. Induction of antitumor activity.

1982 • 79 citations

Role of carbohydrate in the function of human granulocyte-macrophage colony-stimulating factor

1987 • 78 citations

Recombinant murine granulocyte‐macrophage (GM) colony‐stimulating factor supports formation of GM and multipotential blast cell colonies in culture: Comparison with the effects of interleukin‐3

1987 • 77 citations

Biochemistry of macrophages.

1986 • 77 citations

Isolation of haemopoietic spleen colony forming cells.

1986 • 76 citations

Enhancement of human blood eosinophil cytotoxicity by semi-purified eosinophil colony-stimulating factor(s).

1982 • 75 citations

CSF-1 stimulates Na+K+-ATPase mediated 86Rb+ uptake in mouse bone marrow-derived macrophages

1985 • 74 citations

Interferon β2 as a promoter of growth and differentiation of B cells

1987 • 74 citations

Purification of a multipotential colony-stimulating factor from pokeweed mitogen-stimulated mouse spleen cell conditioned medium.

1985 • 72 citations

Stimulation of murine colony-forming cells with high proliferative potential by the combination of GM-CSF and CSF-1

1988 • 72 citations

Stimulation of guanylate cyclase activity and reduction of adenylate cyclase activity by granulocyte-macrophage colony-stimulating factor in human blood neutrophils.

1988 • 71 citations

Colony-stimulating factor 1-induced Na+ influx into human monocytes involves activation of a pertussis toxin-sensitive GTP-binding protein.

1988 • 69 citations

Binding characteristics and proliferative action of purified granulocyte colony-stimulating factor (G-CSF) on normal and leukemic human promyelocytes.

1988 • 68 citations

Recombinant human granulocyte colony-stimulating factor induces granulocytosis in vivo.

1986 • 65 citations

Clonal heterogeneity in colony stimulating factor production by murine T lymphocytes

1985 • 65 citations

Expression and Purification of Native Human Granulocyte-Macrophage Colony-Stimulating Factor from anEscherichia coliSecretion Vector

1987 • 64 citations

Multi-CSF-dependent colony formation by cells of a murine hemopoietic cell line: specificity and action of multi-CSF

1985 • 61 citations

Return of the magnificent seven

1987 • 60 citations

Augmentation of donor bone marrow engraftment in histoincompatible murine recipients by granulocyte/macrophage colony-stimulating factor

1988 • 58 citations

A T cell-derived factor stimulating multipotential hemopoietic stem cells: molecular weight and distinction from T cell growth factor and T cell-derived granulocyte-macrophage colony-stimulating factor.

1982 • 58 citations

Proliferative capacity of mouse peritoneal macrophages in vitro.

1978 • 57 citations

Platelet-activating factor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate stimulates the production of reactive oxygen intermediates in macrophages

1988 • 57 citations

The kinetic response of haemopoietic precursor cells, in vivo, to highly purified, recombinant interleukin-3.

1986 • 57 citations

Affinity isolation of the interleukin-3 surface receptor

1986 • 57 citations

Binding of iodinated recombinant human GM-CSF to the blast cells of acute myeloblastic leukemia.

1988 • 57 citations

Modulation of receptors for the colony-stimulating factor, CSF-1, by bacterial lipopolysaccharide and CSF-1

1984 • 56 citations

Granulocyte-macrophage colony stimulating factor produced by cloned L3T4a+, class II-restricted T cells induces HT-2 cells to proliferate.

1987 • 55 citations

Clonal analysis of the response of HL60 human myeloid leukemia cells to biological regulators

1983 • 54 citations

A hemopoietic cell line dependent upon a factor in pokeweed mitogen‐stimulated spleen cell conditioning medium

1980 • 53 citations

The opposing actions in vivo on murine myelopoiesis of purified preparations of lactoferrin and the colony stimulating factors.

1987 • 52 citations

Regulation of gene expression of M-, G-, GM-, and multi-CSF in normal and malignant hematopoietic cells.

1988 • 52 citations

Experimental Haematology Today

1980 • 52 citations

Internalisation and recycling of the granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) receptor on a murine myelomonocytic leukemia

1987 • 51 citations

Release of granulocyte-macrophage colony stimulating factors from major histocompatibility complex class II antigen-positive monocytes is enhanced by human gamma interferon

1985 • 51 citations

Bone marrow pro‐T and pro‐B lymphocyte clones express functional receptors for interleukin (IL) 3 and IL4/BSF‐1 and nonfunctional receptors for IL2

1987 • 50 citations

Establishment of eosinophilic sublines from human promyelocytic leukemia (HL-60) cells: demonstration of multipotentiality and single- lineage commitment of HL-60 stem cells

1986 • 50 citations

Biochemical comparison of murine colony-stimulating factors secreted by a T cell lymphoma and a myelomonocytic leukemia.

1984 • 49 citations

The Role of the Colony‐Stimulating Factors in Resistance to Acute Infections

1987 • 49 citations

Recombinant murine IL-3 fails to stimulate T or B lymphopoiesis in vivo, but enhances immune responses to T cell-dependent antigens.

1988 • 49 citations

Factors Affecting the Growth and Differentiation of Haemopoietic Cells in Culture

1984 • 49 citations

Recombinant human granulocyte-colony stimulating factor: in vitro and in vivo effects on myelopoiesis.

1987 • 48 citations

Establishment and characterization of an undifferentiated human T leukemia cell line which requires granulocyte-macrophage colony stimulatory factor for growth.

1987 • 48 citations

Biosynthetic granulocyte-macrophage colony-stimulating factor enhances neutrophil cytotoxicity toward human leukemia cells.

1987 • 47 citations

The response of haemopoietic cells to growth factors: developmental implications of synergistic interactions

1988 • 47 citations

Effects of human colony-stimulating factor on the uptake and destruction of a pathogenic parasite (Trypanosoma cruzi) by human neutrophils.

1986 • 46 citations

Independent regulation of granulocyte-macrophage colony-stimulating factor and multi-lineage colony-stimulating factor production in T lymphocyte clones.

1986 • 46 citations

Unicellular or multicellular origin of human granulocyte-macrophage colonies in vitro

1979 • 45 citations

Induction by recombinant human granulocyte colony‐stimulating factor of differentiation of mouse myeloid leukemic M1 cells

1986 • 45 citations

The roles of granulocyte-macrophage colony-stimulating factor and interleukin 3 in stromal cell-mediated hemopoiesis in vivo.

1988 • 44 citations

Induction of IL 2 responsiveness in a murine IL 3-dependent cell line.

1985 • 44 citations

Multilineage hematopoietic growth factor interleukin 3 and direct activators of protein kinase C stimulate phosphorylation of common substrates

1986 • 44 citations

Granulocyte macrophage‐colony stimulating factor stimulates the synthesis of membrane and nuclear proteins in murine neutrophils

1983 • 43 citations

CSF-1 stimulates glucose uptake in murine bone marrow-derived macrophages

1986 • 43 citations

Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor in Patients with Myelodysplastic Syndromes – a Phase-I/II Trial

1988 • 42 citations

Inhibition of interleukin 3 and colony-stimulating factor 1-stimulated marrow cell proliferation by pertussis toxin

1988 • 42 citations

Interleukin-3-stimulated haemopoietic stem cell proliferation. Evidence for activation of protein kinase C and Na+/H+ exchange without inositol lipid hydrolysis

1988 • 42 citations

P‐cell Stimulating Factor: Characterization, Action on Multiple Lineages of Bone‐marrow‐derived Cells and Role in Oncogenesis

1983 • 41 citations

Stromal growth factor production in irradiated lectin exposed long-term murine bone marrow cultures

1987 • 40 citations

Human granulocyte colony-stimulating factor produced by Escherichia coli shortens the period of granulocytopenia induced by irradiation in mice.

1987 • 40 citations

Detection of eosinophil differentiation factor and its relationship to eosinophilia in Mesocestoides corti-infected mice.

1986 • 34 citations

Recombinant T cell replacing factor (interleukin 5) acts with antigen to promote the growth and differentiation of single hapten-specific B lymphocytes.

1987 • 33 citations

Identification of the hematopoietic growth factors elaborated by bone marrow stromal cells using antibody neutralization analysis.

1987 • 33 citations

Persistent production of colony‐stimulating factor (CSF‐1) by cloned bone marrow stromal cell line D2XRII after X‐irradiation

1986 • 32 citations

The influence in vivo of murine colony-stimulating factor-1 on myeloid progenitor cells in mice recovering from sublethal dosages of cyclophosphamide

1987 • 31 citations

High serum colony-stimulating activity of leukocytopenic patients after intravenous infusions of human urinary colony-stimulating factor

1983 • 31 citations

In vivo transfer of persisting (P) cells; further evidence for their identity with T-dependent mast cells.

1984 • 30 citations

Effects of recombinant murine granulocyte colony-stimulating factor on granulocyte-macrophage and blast colony formation.

1987 • 29 citations

Mutagenesis of murine granulocyte/macrophage-colony-stimulating factor reveals critical residues near the N terminus

1987 • 29 citations

Fractionated populations of normal human marrow cells respond to both human colony-stimulating factors with granulocyte-macrophage activity.

1985 • 29 citations

Granulocyte/macrophage colony-stimulating factor from mouse lung conditioned medium. Purification of multiple forms and radioiodination

1986 • 28 citations

The nature of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA)‐stimulated hemopoiesis, colony stimulating factor (CSF) requirement for colony formation, and the effect of TPA on [¹²⁵I]CSF‐1 binding to macrophages

1983 • 28 citations

The in vivo functions and properties of persisting cell-stimulating factor.

1984 • 27 citations

Efficient Secretion and Processing of Heterologous Proteins inSaccharomyces cerevisiaeIs Mediated Solely by the Pre-Segment of α-Factor Precursor

1988 • 25 citations

Receptor-mediated binding and internalization of colony-stimulating factor (csf-1) by mouse peritoneal exudate macrophages

1984 • 25 citations

The colony-stimulating factors and myeloid leukemia

1995 • 21 citations

The production of hematopoietic growth factors by endothelial accessory cells.

1987 • 21 citations

Interferon-induced inhibition of receptor-mediated endocytosis of colony-stimulating factor (CSF-1) by murine peritoneal exudate macrophages.

1986 • 21 citations

The production of lymphokines by primary alloreactive T-cell clones: a co-ordinate analysis of 233 clones in seven lymphokine assays.

1985 • 19 citations

The effect of colony stimulating factor-1 in vivo.

1987 • 17 citations

Enhanced mitogenic responsiveness to granulocyte-macrophage colony-stimulating factor in HL-60 promyelocytic leukemia cells upon induction of differentiation.

1988 • 16 citations

In vivo effect of murine recombinant interleukin 3 on early hemopoietic progenitors

1987 • 15 citations

Some interleukin-3 dependent mast-cell lines also respond to interleukin-2.

1985 • 15 citations

Tumor Cell Differentiation: Biology and Pharmacology

1987 • 13 citations

Role of phorbol ester receptors in the 12‐0‐tetradecanoyl‐phorbol‐13‐acetate (TPA)‐induced down‐regulation of colony‐stimulating factor (CSF‐1) binding to murine peritoneal exudate macrophages

1985 • 13 citations

Constitutive c-myc expression enhances the response of murine mast cells to IL-3, but does not eliminate their requirement for growth factors.

1988 • 13 citations

Partial primary structures of human and murine macrophage colony stimulating factor (CSF-1)

1987 • 12 citations

Tumor‐promoting phorbol esters stimulate the proliferation of interleukin‐3 dependent cells

1988 • 12 citations

Metabolic effects of interleukin 3 on 32D cl23 cells analyzed by NMR

1987 • 10 citations

Enhancement of neutrophil‐mediated phagocytosis by human granulocyte‐macrophage colony‐stimulating factor demonstrated using a novel mathematical model

1987 • 9 citations

Immature megakaryocytes in the mouse: synergistic response to megakaryocyte potentiator, thrombopoietic stimulatory factor with interleukin 3.

1987 • 9 citations

1,25‐dihydroxycholecalciferol‐induced differentiation of myelomonocytic leukemic cells unresponsive to colony stimulating factors and phorbol esters

1986 • 8 citations

The kinetics of s phase entry by FMP2.1: Effect of il‐3 and gm‐csf receptor expression and ligand affinity

1988 • 6 citations

Cytostasis of tumor cell lines by promyelocytic leukemia cell line HL60 differentiated to granulocyte lineage

1985 • 3 citations

Further studies on the mechanism of CFU-S determination—III. CFU-S cell lineage determination is not influenced by GM-CSF, EPO, multi-CSF nor WEHI 3B conditioned medium

1987 • 3 citations

Genetically Determined Regulators Acting on the Blast Cells of Acute Myeloblastic Leukemia

1987 • 3 citations