The Role of the Colony‐Stimulating Factors in Resistance to Acute Infections

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1966 • 1,944 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

1986 • 1,260 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors

1986 • 901 citations

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

1986 • 831 citations

Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells.

1977 • 740 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

Purification and properties of colony-stimulating factor from mouse lung-conditioned medium.

1977 • 624 citations

Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor.

1983 • 568 citations

Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator

1985 • 566 citations

The Hemopoietic Colony-stimulating Factors

1995 • 565 citations

Molecular Cloning of a Complementary DNA Encoding Human Macrophage-Specific Colony-Stimulating Factor (CSF-1)

1985 • 542 citations

Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor.

1985 • 522 citations

Purified Human Granulocyte-Macrophage Colony-Stimulating Factor: Direct Action on Neutrophils

1984 • 506 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

1984 • 451 citations

Procedures for the purification of interleukin 3 to homogeneity.

1982 • 428 citations

Stimulation of haematopoiesis in primates by continuous infusion of recombinant human GM-CSF

1986 • 405 citations

Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor, and colony stimulating activity.

1986 • 397 citations

In vitro control of the development of macrophage and granulocyte colonies.

1966 • 385 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

Hierarchical down-modulation of hemopoietic growth factor receptors

1985 • 314 citations

Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice

1986 • 313 citations

Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity

1985 • 273 citations

Production of lymphocyte-activating factor (Interleukin 1) by macrophages activated with colony-stimulating factors.

1980 • 272 citations

Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factors

1986 • 269 citations

Activation of antibody-dependent cell-mediated cytotoxicity of human neutrophils and eosinophils by separate colony-stimulating factors.

1983 • 248 citations

Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues.

1981 • 239 citations

Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3.

1986 • 238 citations

The Human Gene Encoding GM-CSF Is at 5q21-q32, the Chromosome Region Deleted in the 5q ^- Anomaly

1985 • 237 citations

Evidence for the Involvement of GM-CSF and FMS in the Deletion (5q) in Myeloid Disorders

1986 • 233 citations

Stimulation by Granulocyte-Macrophage Colony-Stimulating Factor of Leishmania Tropica Killing by Macrophages

1979 • 227 citations

Stimulation of macrophage plasminogen activator activity by colony‐stimulating factors

1980 • 223 citations

Proliferative effects of purified granulocyte colony‐stimulating factor (G‐CSF) on normal mouse hemopoietic cells

1983 • 221 citations

Binding of125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic cells

1985 • 215 citations

Acute antigen-induced elevation of serum colony stimulating factor (CFS) levels.

1971 • 206 citations

Activation of granulocyte cytotoxic function by purified mouse colony-stimulating factors.

1983 • 193 citations

Induction of prostaglandin E synthesis in normal and neoplastic macrophages: role for colony-stimulating factor(s) distinct from effects on myeloid progenitor cell proliferation.

1979 • 189 citations

Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor

1978 • 161 citations

In vitro actions on hemopoietic cells of recombinant murine GM‐CSF purified after production in Escherichia coli: Comparison with purified native GM‐CSF

1986 • 149 citations

Clonal analysis of proliferation and differentiation of paired daughter cells: action of granulocyte-macrophage colony-stimulating factor on granulocyte-macrophage precursors.

1980 • 147 citations

Clonal analysis of progenitor cell commitment to granulocyte or macrophage production

1982 • 145 citations

The structure and expression of the murine gene encoding granulocyte-macrophage colony stimulating factor: evidence for utilisation of alternative promoters.

1985 • 129 citations

Synthesis by mouse peritoneal cells of G-CSF, the differentiation inducer for myeloid leukemia cells: Stimulation by endotoxin, M-CSF and multi-CSF

1985 • 124 citations

Characterization of the cell surface receptor for a multi-lineage colony-stimulating factor (CSF-2 alpha).

1986 • 122 citations

Colony stimulating factor and the regulation of granulopoiesis and macrophage production.

1975 • 122 citations

Recombinant murine GM-CSF from E. coli has biological activity and is neutralized by a specific antiserum.

1985 • 121 citations

Granulocyte-macrophage colony-stimulating and binding activities of purified human urinary colony-stimulating factor to murine and human bone marrow cells

1982 • 91 citations

Binding of iodinated multipotential colony‐stimulating factor (interleukin‐3) to murine bone marrow cells

1986 • 85 citations

Studies on the bone marrow colony stimulating factor (CSF): Relation of tissue CSF to serum CSF

1972 • 77 citations

Enhancement of human blood eosinophil cytotoxicity by semi-purified eosinophil colony-stimulating factor(s).

1982 • 75 citations

Pluripoietin alpha: a second human hematopoietic colony-stimulating factor produced by the human bladder carcinoma cell line 5637.

1986 • 74 citations

Clonal heterogeneity in colony stimulating factor production by murine T lymphocytes

1985 • 65 citations

Effects of GM‐CSF deprivation on precursors of granulocytes and macrophages

1982 • 65 citations

The kinetic response of haemopoietic precursor cells, in vivo, to highly purified, recombinant interleukin-3.

1986 • 57 citations

Mononuclear cell-mediated enhancement of granulocyte function in man.

1984 • 57 citations

Eosinophil activation by colony-stimulating factor in man: metabolic effects and analysis by flow cytometry

1983 • 47 citations

Granulocyte macrophage‐colony stimulating factor stimulates the synthesis of membrane and nuclear proteins in murine neutrophils

1983 • 43 citations

Interferon induction in marrow‐derived macrophages: Regulation by L cell conditioned medium

1981 • 40 citations

Induced release and metabolism of arachidonic acid from myeloid cells by purified colony‐stimulating factor

1982 • 22 citations

Selective enhancement of the expression of granulocyte functional antigens 1 and 2 on human neutrophils.

1985 • 13 citations

The Multipotential Colony-Stimulating Factor, Multi-CSF (IL-3)

1988 • 12 citations

A granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) produced by carrageenin‐induced inflammatory cells of mice

1981 • 7 citations