The Hemopoietic Colony-stimulating Factors

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1966 • 1,944 citations

Human bone marrow colony growth in agar‐gel

1970 • 1,317 citations

Purification of human erythropoietin.

1977 • 893 citations

Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells.

1977 • 740 citations

Purification and properties of colony-stimulating factor from mouse lung-conditioned medium.

1977 • 624 citations

Induction of Colonies of Hemoglobin-Synthesizing Cells by Erythropoietin In Vitro

1971 • 620 citations

Erythroid progenitors in mouse bone marrow detected by macroscopic colony formation in culture.

1975 • 444 citations

Demonstration of granulopoietic factor(s) in the plasma of nude mice transplanted with a human lung cancer and in the tumor tissue

1977 • 438 citations

Stimulation by human placental conditioned medium of hemopoietic colony formation by human marrow cells

1977 • 394 citations

In vitro control of the development of macrophage and granulocyte colonies.

1966 • 385 citations

Human Blood Monocytes: Stimulators of Granulocyte and Mononuclear Colony Formation in vitro

1972 • 374 citations

MECHANISM OF EOSINOPHILIA

1970 • 374 citations

The induction of clones of normal mast cells by a substance from conditioned medium

1966 • 358 citations

Pure and mixed erythroid colony formation in vitro stimulated by spleen conditioned medium with no detectable erythropoietin.

1977 • 334 citations

Human erythroid burst-forming unit: T-cell requirement for proliferation in vitro.

1978 • 324 citations

Partial replacement of serum by selenite, transferrin, albumin and lecithin in haemopoitec cell cultures

1976 • 319 citations

Identification of the colony-stimulating cell in human peripheral blood

1972 • 301 citations

Identification of lactoferrin as the granulocyte-derived inhibitor of colony-stimulating activity production.

1978 • 293 citations

Growth of mouse megakaryocyte colonies in vitro.

1975 • 289 citations

Factors regulating macrophage production and growth: identity of colony-stimulating factor and macrophage growth factor.

1976 • 263 citations

Erythropoietic Colonies in Cultures of Human Marrow

1974 • 262 citations

In Vitro Induction of Granulocyte Differentiation in Hematopoietic Cells from Leukemic and Non-Leukemic Patients

1970 • 253 citations

THE ROLE OF ERYTHROPOIETIN IN REGULATION OF POPULATION SIZE AND CELL CYCLING OF EARLY AND LATE ERYTHROID PRECURSORS IN MOUSE BONE MARROW

1977 • 251 citations

Effect of Endotoxin on Granulopoiesis and Colony-Stimulating Factor

1972 • 248 citations

Role for monocyte-macrophage-derived colony-stimulating factor and prostaglandin E in the positive and negative feedback control of myeloid stem cell proliferation

1978 • 234 citations

Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor

1970 • 233 citations

Stimulation by Granulocyte-Macrophage Colony-Stimulating Factor of Leishmania Tropica Killing by Macrophages

1979 • 227 citations

The effect of oxygen tension on haemopoietic and fibroblast cell proliferation in vitro

1978 • 227 citations

Characterization of the factor in L‐cell conditioned medium capable of stimulating colony formation by mouse marrow cells in culture

1971 • 222 citations

Production of Colony-Stimulating Factor in Mitogen-Stimulated Lymphocyte Cultures

1974 • 213 citations

Acute antigen-induced elevation of serum colony stimulating factor (CFS) levels.

1971 • 206 citations

Hemopoietic colonies: in vitro cloning of normal and leukemic cells.

1977 • 202 citations

In Vitro Growth of Granulocytic and Mononuclear Cell Colonies From Blood of Normal Individuals

1971 • 202 citations

Separation of functionally distinct human granulocyte-macrophage colony- stimulating factors

1979 • 200 citations

Production of colony-stimulating activity by human lymphocytes

1974 • 192 citations

Stimulation by normal and leukemic mouse sera of colony formation in vitro by mouse bone marrow cells

1967 • 192 citations

Direct stimulation by purified GM-CSF of the proliferation of multipotential and erythroid precursor cells

1980 • 188 citations

FACTORS FROM MOUSE TISSUES STIMULATING COLONY GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1971 • 187 citations

Induction of megakaryocyte colonies with platelet formation in vitro

1976 • 182 citations

Studies of Leukemic Cell Populations in Culture

1974 • 179 citations

A low molecular weight factor in lung‐conditioned medium stimulating granulocyte and monocyte colony formation in vitro

1973 • 172 citations

Erythroid colony formation in cultures of human marrow: Effect of leukocyte conditioned medium

1977 • 163 citations

Colony-stimulating factor (CSF) radioimmunoassay: detection of a CSF subclass stimulating macrophage production.

1979 • 162 citations

Separation of the erythropoietin-responsive progenitors BFU-E and CFU-E in mouse bone marrow by unit gravity sedimentation

1976 • 162 citations

Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor

1978 • 161 citations

Colony formation in agar by multipotential hemopoietic cells

1979 • 159 citations

STIMULATION OF MOUSE BONE MARROW COLONY GROWTH IN VITRO BY CONDITIONED MEDIUM

1968 • 157 citations

In Vitro Colony Assay for a New Class of Megakaryocyte Precursor: Colony-Forming Unit Megakaryocyte (CFU-M)

1976 • 151 citations

Purification and characterisation of the in vitro colony forming cell in monkey hemopoietic tissue

1972 • 151 citations

Formation of eosinophilic‐like granulocytic colonies by mouse bone marrow cells in vitro

1974 • 148 citations

Regulation of megakaryopoiesis in long-term murine bone marrow cultures

1978 • 144 citations

Colony Formation <italic>In Vitro</italic> by Myelomonocytic Leukemic Cells<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1969 • 138 citations

Evidence that Lithium Induces Human Granulocyte Proliferation: Elevated Serum Vitamin B₁₂ Binding Capacity in Vivo and Granulocyte Colony Proliferation in Vitro

1973 • 135 citations

Human cell lines that elaborate colon-stimulating activity for the marrow cells of man and other species

1978 • 133 citations

Stimulation and Inhibition by Normal Human Serum of Colony Formation in Vitro by Bone Marrow Cells

1971 • 133 citations

Granulocyte/macrophage-, megakaryocyte-, eosinophil- and erythroid-colony-stimulating factors produced by mouse spleen cells

1980 • 132 citations

In Vitro Colony Formation by Normal and Leukemic Human Hematopoietic Cells: Interaction Between Colony-Forming and Colony-Stimulating Cells2

1973 • 131 citations

Theta-Sensitive Cell and Erythropoiesis: Identification of a Defect in W / W ^v Anemic Mice

1977 • 129 citations

Enhancement of colony-stimulating activity production by lithium

1977 • 128 citations

PARTIAL PURIFICATION AND SOME PROPERTIES OF THE FACTOR IN NORMAL AND LEUKAEMIC HUMAN URINE STIMULATING MOUSE BONE MARROW COLONY GROWTH IN VITRO

1969 • 126 citations

Bone Marrow Colony Stimulating Activity in Human Sera. RESULTS OF TWO INDEPENDENT SURVEYS IN BUFFALO AND MELBOURNE*

1968 • 125 citations

Specific release of neutrophillic- and eosinophilic-stimulating factors from sensitized lymphocytes

1976 • 124 citations

Production by spleen and lymph node cells of conditioned medium with erythroid and other hemopoietic colony‐stimulating activity

1978 • 124 citations

Direct toxic effects of immunopotentiators on monocytic, myelomonocytic, and histiocytic or macrophage tumor cells in culture.

1977 • 122 citations

Colony stimulating factor and the regulation of granulopoiesis and macrophage production.

1975 • 122 citations

Similar molecular properties of granulocyte-macrophage colony-stimulating factors produced by different mouse organs in vitro and in vivo.

1979 • 119 citations

Physical separation of colony stimulating cells from in vitro colony forming cells in hemopoietic tissue

1972 • 118 citations

Tissue sources of bone marrow colony stimulating factor

1971 • 117 citations

Heterogeneity of in vitro colony‐ and cluster‐forming cells in the mouse marrow: Segregation by velocity sedimentation

1975 • 117 citations

Cell-free granulocyte colony inhibiting activity derived from human polymorphonuclear neutrophils.

1977 • 107 citations

In vivo induction of normal differentiation in myeloid leukemia cells

1978 • 103 citations

Haematological Effects in Mice of Partially Purified Colony Stimulating Factor (CSF) Prepared from Human Urine

1971 • 103 citations

Cyclic hematopoiesis: the mechanism of cyclic neutropenia in grey collie dogs

1972 • 102 citations

Clonal analysis of the action of GM‐CSF on the proliferation and differentiation of myelomonocytic leukemic cells

1979 • 101 citations

Characterization of the Inducer Required for the Development of Macrophage and Granulocyte Colonies

1971 • 101 citations

IN VITRO PRODUCTION OF COLONY‐STIMULATING ACTIVITY. I. EXPOSURE OF MOUSE PERITONEAL CELLS TO ENDOTOXIN

1974 • 99 citations

Brief Report: Stimulation of Bone Marrow Colony Growth In Vitro by Human Urine

1969 • 98 citations

Release of colony-stimulating activity from thymus-derived lymphocytes.

1975 • 97 citations

Peritoneal exudate cells. I. Growth requirement of cells capable of forming colonies in soft agar

1974 • 93 citations

Felty's syndrome

1976 • 92 citations

Kinetics of Haemopoietic Colony Growth

1971 • 88 citations

Local Production of Colony-stimulating Factor Within the Bone Marrow: Role of Nonhematopoietic Cells

1972 • 87 citations

The continued requirement for inducer for the development of macrophage and granulocyte colonies

1968 • 85 citations

Monocyte Production of Colony Stimulating Factor in Familial Cyclic Neutropenia

1974 • 83 citations

The isolation and properties of granulocytic colony-stimulating activities from medium conditioned by human peripheral leucocytes

1975 • 82 citations

Bone Marrow Colony-Stimulating Activity of Serum From Mice With Viral-Induced Leukemia<xref ref-type="fn" rid="FN1">2</xref>

1967 • 81 citations

Isolation and surface labeling of murine polymorphonuclear neutrophils

1979 • 81 citations

Cytochemical and Morphologic Identification of Macrophages and Eosinophils in Tissue Cultures of Normal Human Bone Marrow

1974 • 81 citations

Preferential inhibition of murine macrophage colony formation by prostaglandin E

1979 • 79 citations

Studies on the bone marrow colony stimulating factor (CSF): Relation of tissue CSF to serum CSF

1972 • 77 citations

Erythropoietin-Independence of Early Erythropoiesis and a Two-Regulator Model of Proliferative Control in the Hemopoietic System

1978 • 75 citations

Detection of a new type of mouse eosinophil colony by Luxol-fast-blue staining.

1980 • 75 citations

Growth stimulation of human bone marrow cells in agar culture by vascular cells

1975 • 74 citations

Preparation of colony stimulating factors from human placental conditioned medium

1978 • 72 citations

Tolerance to the granulocyte-releasing and colony-stimulating factor elevating effects of endotoxin

1975 • 71 citations

Colony-stimulating Factor and Inhibitor Levels in Acute Granulocytic Leukemia

1971 • 69 citations

Regulation of Platelet Production: ‘Thrombopoietin’

1967 • 68 citations

CONTROL OF GRANULOCYTE PRODUCTION: SEPARATION AND CHEMICAL IDENTIFICATION OF A SPECIFIC INHIBITOR (CHALONE)

1971 • 67 citations

QUANTITATIVE STUDIES ON THE STIMULATION OF MOUSE BONE MARROW COLONY GROWTH IN VITRO BY NORMAL HUMAN URINE

1969 • 67 citations

Control of macrophage and granulocyte colony formation by two different factors

1977 • 67 citations

Behavior on Transfer of Serum Stimulated Bone Marrow Colonies.

1967 • 66 citations

Characterization of colony-stimulating activity produced by human monocytes and phytohemagglutinin-stimulated lymphocytes

1977 • 65 citations

Regulation of proliferation of murine megakaryocyte progenitor cells by cell cycle

1978 • 62 citations

Molecular and biological properties of a macrophage colony-stimulating factor from mouse yolk sacs

1978 • 62 citations

Preparation and neutralization characteristics of an anti-CSF antibody

1975 • 62 citations

Antigenic stimulation of bone marrow colony forming cells. 3. Effect in vivo.

1970 • 61 citations

LYMPHOID CELL DEPENDENCE OF EOSINOPHIL RESPONSE TO ANTIGEN

1971 • 61 citations

The effect of colony stimulating factor on the synthesis of ribonucleic acid by mouse bone marrow cells in vitro

1977 • 60 citations

Release of colony-stimulating factor from monocytes by endotoxin and polyinosinic-polycytidylic acid.

1974 • 59 citations

Eosinophil colony formation in semisolid cultures of human bone marrow cells

1977 • 57 citations

Separation of subpopulations of in vitro colony forming cells from mouse marrow by equilibrium density centrifugation

1975 • 57 citations

Human marrow erythropoiesis in culture: II. Heterogeneity in the morphology, time course of colony formation, and sedimentation velocities of the colony‐forming cells

1977 • 56 citations

Some Factors Influencing Granulocytic Colony Formation In Vitro by Human White Blood Cells

1974 • 54 citations

Properties of the mouse embryo conditioned medium factor(s) stimulating colony formation by mouse bone marrow cells grown in vitro

1971 • 54 citations

Production of colony-stimulating factor in mixed leucocyte cultures.

1974 • 54 citations

Immunostimulators induce granulocyte/macrophage colony-stimulating activity and block proliferation in a monocyte tumor cell line.

1977 • 53 citations

Genetic control of lipopolysaccharide induced generation of serum colony stimulating factor and proliferation of splenic granulocyte/macrophage precursor cells

1976 • 53 citations

Effect of endotoxin and postendotoxin plasma on in vitro granulopoiesis.

1972 • 53 citations

Modulation of myelopoiesis by different bacterial cell-wall components: Induction of colony-stimulating activity (by pure preparations, low-molecular-weight degradation products and a synthetic low-molecular analog of bacterial cell-wall components) in vitro

1978 • 51 citations

Inhibition in vivo of mouse granulopoiesis by cell-free activity derived from human polymorphonuclear neutrophils

1978 • 51 citations

Cortisone Action on Serum Colony-Stimulating Factor and Bone Marrow in Vitro Colony-Forming Cells

1969 • 50 citations

Maturation and regulation of megakaryocytopoiesis.

1979 • 49 citations

Effect of Corynebacterium parvum on colony-stimulating factor and granulocyte-macrophage colony formation.

1977 • 49 citations

The maturation state of three types of granulocyte/macrophage progenitor cells from mouse bone marrow

1980 • 49 citations

THE PRESENCE OF A CSF ENHANCING ACTIVITY IN THE SERUM OF ENDOTOXIN‐TREATED MICE

1975 • 49 citations

Endotoxin-Induced Release of Colony-Stimulating Activity in Man

1975 • 49 citations

Interacting populations affecting proliferation of leukemic cells in culture

1975 • 48 citations

Colony-Stimulating Factors in Cultures of Human Peripheral Blood Cells&lt;xref ref-type="fn" rid="fn2"&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/xref&gt;

1974 • 48 citations

Marrow adherent cell colony-stimulating activity production in acute myeloid leukemia

1978 • 48 citations

Cyclic Neutropenia: The Relationship Between Urine Granulocyte Colony Stimulating Activity and Neutrophil Count

1973 • 46 citations

Release of Bone Marrow Colony Stimulating Activity during Immunological Reactions in vitro

1973 • 46 citations

QUANTITATIVE IN VITRO STUDIES ON STIMULATION OF MURINE HAEMOPOIETIC CELLS BY COLONY STIMULATING FACTOR

1974 • 46 citations

LOCAL AND SYSTEMIC CONTROL OF GRANULOCYTIC AND MACROPHAGE PROGENITOR CELL REGENERATION AFTER IRRADIATION

1973 • 46 citations

Peritoneal Cell Population of Mice Infected with &lt;i&gt;Mesocestoides corti&lt;/i&gt; as a Source of Eosinophils

1979 • 45 citations

Bone Marrow Colony-stimulating Activity of Sera in Infectious Mononucleosis

1968 • 44 citations

The Effects of Whole Body Irradiation on Serum Colony Stimulating Factor and in Vitro Colony‐Forming Cells in the Bone Marrow

1969 • 44 citations

Colony stimulating activity of serum from germfree normal and leukemic mice

1967 • 44 citations

Nature of cells forming erythroid colonies in agar after stimulation by spleen conditioned medium

1978 • 42 citations

Interactions between purified GM‐CSF, purified erythropoietin and spleen conditioned medium on hempoietic colony formation in vitro

1979 • 38 citations

Influence of serum inhibitors on colony development in vitro by bone marrow cells.

1971 • 37 citations

Changes in hemopoiesis during the course of acute LCM virus infection in mice

1977 • 37 citations

Granulocyte-Macrophage Precursor Cell and Colony-Stimulating Factor Responses of Mice Infected with Salmonella typhimurium

1973 • 36 citations

Further studies on the factor in lung‐conditioned medium stimulating granulocyte and monocyte colony formation in vitro

1974 • 36 citations

T-cell hybridoma secreting hemopoietic regulatory molecules: Granulocyte-macrophage and eosinophil colony-stimulating factors

1979 • 36 citations

Serum Colony Stimulating Factor Levels in Irradiated Germfree and Conventional GFW Mice

1972 • 36 citations

THE IN VITRO DIFFERENTIATION OF DENSITY SUB‐POPULATIONS OF COLONY‐FORMING CELLS UNDER THE INFLUENCE OF DIFFERENT TYPES OF COLONY‐STIMULATING FACTOR

1977 • 35 citations

Production of hemopoietic stimulating factors by pokeweed-mitogen-stimulated spleen cells.

1978 • 35 citations

Inhibition by mouse serum of hemopoietic colony formation in vitro.

1976 • 35 citations

ULTRASTRUCTURAL ANALYSIS OF HEMATOPOIETIC COLONIES DERIVED FROM HUMAN PERIPHERAL BLOOD

1974 • 34 citations

Proliferation of macrophage and granulocyte precursors in response to primary and transplanted tumors.

1971 • 33 citations

Possible mechanisms of action of lithium on augmentation of in vitro spontaneous myeloid colony formation.

1979 • 33 citations

Megakaryocytes in agar cultures of mouse bone marrow.

1975 • 32 citations

Inhibition of Diffusion Chamber (DC) Granulopoiesis by Anti-CSF Serum

1978 • 32 citations

INDUCTION OF BONE MARROW COLONY-STIMULATING ACTIVITY BY A FILTERABLE AGENT IN LEUKEMIC AND NORMAL MOUSE SERUM

1968 • 32 citations

Human Cyclic Neutropenia: Urinary Colony-stimulating Factor and Erythropoietin Levels

1974 • 31 citations

Eosinophil and neutrophil colony-forming cells in culture

1977 • 31 citations

Inhibition of agar colony formation by partially purified granulocyte extracts (chalone)

1977 • 31 citations

Serum half-life and organ distribution of radiolabeled colony stimulating factor in mice.

1977 • 31 citations

Fractionation of antibodies to L-cell colony-stimulating factor by affinity chromatography

1979 • 29 citations

Stimulation by human urine or plasma of granulopoiesis by human marrow cells in agar.

1974 • 28 citations

Cellular responsiveness to stimulation in vitro: Strain differences in hemopoietic colony forming cell responsiveness to stimulating factor and suppression of responsiveness by glucocorticoids

1973 • 28 citations

Serum potentiation of granulocyte and macrophage colony formation in vitro.

1975 • 28 citations

An amplifier cell in hemopoiesis.

1978 • 28 citations

Ultrastructure and cytochemistry of bone marrow granulocytes in culture.

1976 • 28 citations

A diffusible stimulator of eosinophilopoiesis produced by lymphoid cells as demonstrated with diffusion chambers

1976 • 27 citations

Cyclic expression of a growth conditioning factor (MGF) on the cell surface

1974 • 27 citations

Molecular weight and some chemical properties of the Granulocytic Chalone

1978 • 26 citations

Alteration of colony‐stimulating factor output, endotoxemia, and granulopoiesis in cyclic neutropenia

1976 • 25 citations

The isolation and characterization of a colony stimulating factor from human lung

1977 • 25 citations

Cell membranes as sources of granulocyte colony stimulating activities.

1975 • 25 citations

Granulocyte kinetics in health and disease.

1969 • 24 citations

Bacterial, serum and cellular modulation of granulopoietic activity

1977 • 23 citations

Studies on inhibitors of bone marrow colony formation in normal human sera and during a viral infection

1973 • 23 citations

Inhibitors of the bone‐marrow colony formation in sera of patients with leukemia

1972 • 21 citations

Production of Colony Stimulating Factors by Lymphoid Tissues

1979 • 21 citations

Effects of fibroblasts on the growth of erythroid progenitor cells in vitro.

1977 • 20 citations

Erythropoietic precursors in murine blood.

1977 • 20 citations

Production of differentiation-stimulating factor in cultured mouse myeloid leukemia cells treated by glucocorticoids

1978 • 20 citations

Studies on Colony-Stimulating Factor (CSF): Role of the Kidney in Clearing Serum CSF

1970 • 19 citations

Bacillus Calmette-Guérin enhancement of colony-stimulating activity and myeloid colony formation following administration of cyclophosphamide.

1979 • 19 citations

Sources and nature of granulocyte-macrophage colony stimulating factor in fetal mice.

1978 • 18 citations

Serum Half Life in Mice of Colony Stimulating Factor Prepared from Human Urine

1971 • 17 citations

Colony-stimulating factors active on human bone marrow cells from a Yoshida sarcoma cell line

1978 • 16 citations

Effects of Microbial Flora on Levels of Colony Stimulating Factor in Serums of Irradiated CFW Mice

1973 • 16 citations

Granulocyte modulation of endotoxin-stimulated colony-stimulating activity (CSA) production

1978 • 16 citations

Humoral granulopoietic inhibitors: a review.

1975 • 15 citations

The Control of Neutrophil and Macrophage Production at the Progenitor Cell Level

1978 • 14 citations

Characterization of mouse fetal liver granulocyte-macrophage colony-forming cells using velocity sedimentation.

1978 • 14 citations

Hemopoietic Colony-Forming Cell Responses in Mice Infected with Ectromelia Virus

1971 • 14 citations

Lack of effect of a granulocyte proliferation inhibitor or their committed precursor cells.

1977 • 12 citations

Starting procedures for the isolation and purification of granulocyte chalone activities

1976 • 12 citations

Depressed responses of the granulocyte-macrophage system to bacterial antigens following preimmunization.

1974 • 11 citations

Amplification of colony stimulating activity in human serum by interaction with CSA from other sources.

1975 • 11 citations

The effect of syngeneic lymphoid tumors upon mouse B-lymphocyte and granulocyte-macrophage colony forming cells

1978 • 10 citations

Cell growth regulating factors in viral infections and other diseases

1971 • 9 citations

Diminished response of granulocyte-macrophage colony-stimulating factor (GM-CSF) in mice after sensitisation with bacterial cell-wall components.

1980 • 8 citations

Synergism between lymph node and bone marrow cells for production of granulocytes. II. Enhanced colony-stimulating activity of sera of mice with graft-versus-host reaction.

1974 • 8 citations

The Bone Marrow Colony Stimulating Factor (CSF): Relation of Serum CSF to Urine CSF

1973 • 8 citations

In Vitro Aspects of Erythropoietin Production

1978 • 7 citations

Bone Marrow Colony-Stimulating Factor Following Ureteral Ligation in Germfree Mice

1970 • 7 citations

The influence of mouse sera on colony formation and on the production of colony stimulating factor in vitro.

1975 • 5 citations

Recent Advances in Erythropoietin Physiology

1978 • 3 citations

Haemopoietic progenitor-cell responses in mice with the transplanted lymphoid leukaemia ABE-8

1979 • 2 citations

Bone marrow colony stimulating factor (CSF) and inhibitor levels in renal disease.

1972 • 1 citations