Interleukin 3 promotes the in vitro proliferation of murine pluripotent hematopoietic stem cells.

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells

1961 • 3,579 citations

Growth of factor-dependent hemopoietic precursor cell lines.

1980 • 793 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse

1984 • 527 citations

The Effect of Differing Demands for Blood Cell Production on DNA Synthesis by Hemopoietic Colony-Forming Cells of Mice

1965 • 515 citations

Properties of haematopoietic stem cells surviving 5-fluorouracil treatment: evidence for a pre-CFU-S cell?

1979 • 513 citations

Procedures for the purification of interleukin 3 to homogeneity.

1982 • 428 citations

Transient nature of early haematopoietic spleen colonies

1982 • 377 citations

Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies.

1982 • 317 citations

Three stages of erythropoietic progenitor cell differentiation distinguished by a number of physical and biologic properties

1978 • 269 citations

Regulation of T cell differentiation: in vitro induction of 20 alpha-hydroxysteroid dehydrogenase in splenic lymphocytes from athymic mice by a unique lymphokine.

1981 • 252 citations

Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors.

1984 • 233 citations

Molecules stimulating early red cell, granulocyte, macrophage, and megakaryocyte precursors in culture: Similarity in size, hydrophobicity, and charge

1982 • 207 citations

A stochastic model of self‐renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture

1982 • 199 citations

A cloned MCGF cDNA encodes a multilineage hematopoietic growth factor: multiple activities of interleukin 3.

1985 • 174 citations

An Inhibitor of Stem Cell Proliferation in Normal Bone Marrow

1976 • 160 citations

Colony formation in agar by multipotential hemopoietic cells

1979 • 159 citations

Phenotypic characteristics of cell lines requiring interleukin 3 for growth.

1982 • 158 citations

Regulation of haemopoietic stem cell proliferation in long term bone marrow cultures.

1977 • 151 citations

Proliferative kinetics and differentiation of murine blast cell colonies in culture: Evidence for variable G₀ periods and constant doubling rates of early pluripotent hemopoietic progenitors

1983 • 145 citations

Granulocyte/macrophage-, megakaryocyte-, eosinophil- and erythroid-colony-stimulating factors produced by mouse spleen cells

1980 • 132 citations

Production by spleen and lymph node cells of conditioned medium with erythroid and other hemopoietic colony‐stimulating activity

1978 • 124 citations

The effect of interleukin 3 and GM-CSA-2 on megakaryocyte and myeloid clonal colony formation

1985 • 121 citations

Thy‐1 determinants are present on many murine hematopoietic Cells other than T Cells

1982 • 121 citations

Computer Simulation of Granulopoiesis: Normal and Impaired Granulopoiesis

1970 • 117 citations

The regulation of hemopoiesis in long-term bone marrow cultures. II. Stimulation and inhibition of stem cell proliferation

1980 • 115 citations

A stimulator of stem cell proliferation in regenerating bone marrow.

1977 • 105 citations

Interleukin 3-dependent hematopoietic progenitor cell lines.

1983 • 83 citations

The effect of interleukin 3 and GM-CSA-2 on megakaryocyte and myeloid clonal colony formation

1985 • 82 citations

Patterns of Proliferation and Differentiation of Hematopoietic Stem Cells After Compartment Depletion

1971 • 73 citations

Expression of Thy-1 antigen is not limited to T cells in cultures of mouse hemopoietic cells.

1982 • 70 citations

Manipulation of the cell cycle of the hemopoietic stem cell.

1975 • 66 citations

A T cell-derived factor stimulating multipotential hemopoietic stem cells: molecular weight and distinction from T cell growth factor and T cell-derived granulocyte-macrophage colony-stimulating factor.

1982 • 58 citations

Stimulation of bone marrow haemopoietic stem cells by a factor from activated T cells

1974 • 58 citations

An antigenic difference between cells forming early and late haematopoietic spleen colonies (CFU-S)

1984 • 50 citations

Factors Affecting the Growth and Differentiation of Haemopoietic Cells in Culture

1984 • 49 citations

Multiple hemopoietic lineages are found after stimulation of mouse bone marrow precursor cells with interleukin 3.

1984 • 47 citations

CFU-S in individual erythroid colonies derived in vitro from adult mouse marrow

1979 • 45 citations

Thy-1 antigen expression by murine high-proliferative capacity hematopoietic progenitor cells. I. Relation between sensitivity to depletion by Thy-1 antibody and stem cell generation potential.

1984 • 44 citations

A preliminary report: preparations containing Interleukin-3 (IL-3) promote proliferation of multipotential stem cells (CFUs) in the mouse.

1983 • 40 citations

Quantitative Histology of Spleen Colonies in Irradiated Mice

1968 • 39 citations

Thy‐1 is a differentiation antigen that characterizes immature murine erythroid and myeloid hematopoietic progenitors

1985 • 23 citations

Three stages of erythropoietic progenitor cell differentiation distinguished by a number of physical and biologic properties

1978 • 21 citations

The regulation of hemopoiesis in long-term bone marrow cultures. II. Stimulation and inhibition of stem cell proliferation

1980 • 4 citations