Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

A New Mouse Myeloma Cell Line that Has Lost Immunoglobulin Expression but Permits the Construction of Antibody-Secreting Hybrid Cell Lines

1979 • 1,885 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

Structure and expression of a cloned cDNA for human interleukin-2

1983 • 1,176 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

A plaque assay for all cells secreting Ig of a given type or class

1976 • 1,034 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Murine Sarcoma and Leukemia Viruses: Assay Using Clonal Lines of Contact-Inhibited Mouse Cells

1969 • 821 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

A new dominant hybrid selective marker for higher eukaryotic cells

1981 • 662 citations

Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities.

1986 • 529 citations

Continuous proliferation of murine antigen-specific helper T lymphocytes in culture.

1979 • 522 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

Interleukin 2

1984 • 497 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Synthesis in E. coli of a polypeptide with human leukocyte interferon activity

1980 • 484 citations

Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter

1986 • 480 citations

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

1984 • 451 citations

Regulation of B-Cell Growth and Differentiation by Soluble Factors

1983 • 432 citations

Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II

1986 • 405 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

Factors Affecting B-Cell Growth and Differentiation

1985 • 354 citations

Molecular cloning of human interleukin 2 cDNA and its expression inE. coli

1983 • 307 citations

Helper-independent transformation by unintegrated Harvey sarcoma virus DNA

1978 • 277 citations

Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity

1985 • 273 citations

Spontaneous murine B-cell leukaemia

1978 • 264 citations

Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12.

1979 • 238 citations

Constitutive production of a unique lymphokine (IL 3) by the WEHI-3 cell line.

1982 • 227 citations

Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.

1982 • 180 citations

Cytotoxic T lymphocytes against a soluble protein

1987 • 178 citations

Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit.

1983 • 176 citations

Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector.

1981 • 172 citations

Expression and characterization of the product of a human immune interferon cDNA gene in Chinese hamster ovary cells.

1983 • 167 citations

Transformation of mouse fibroblasts to methotrexate resistance by a recombinant plasmid expressing a prokaryotic dihydrofolate reductase.

1981 • 164 citations

A New Selective Agent for Eukaryotic Cloning Vectors

1980 • 131 citations

Factors Controlling the B-Cell Cycle

1986 • 116 citations

Ly1+ PRO-B lymphocyte clones. Phenotype, growth requirements and differentiation in vitro and in vivo.

1987 • 113 citations

BCGFII activity on activated B cells of a purified murine T cell-replacing factor (TRF) from a T cell hybridoma (B151K12).

1985 • 100 citations

Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin.

1985 • 98 citations

Transfer of a cloned immunoglobulin light-chain gene to mutant hybridoma cells restores specific antibody production

1983 • 78 citations

Production of interleukin 3 and gamma-interferon by an antigen-specific mouse suppressor T cell clone.

1985 • 77 citations

Secretion of IgG₁ induction factor by T cell clones and hybridomas

1985 • 68 citations

Constitutive, long-term production of human interferons by hamster cells contalning multiple copies of a cloned interferon gene

1983 • 65 citations

Plasmidial maintenance in rodent fibroblasts of a BPV1-pBR322 shuttle vector without immediately apparent oncogenic transformation of the recipient cells.

1984 • 49 citations

Control of the Cell Cycle of Murine B Lymphocytes: The Nature of α‐ and β‐B‐Cell Growth Factors and of B‐Cell Maturation Factors

1987 • 32 citations