Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-γ, IL-4, IL-10 and IL-13) in patients with allergic asthma

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

1991 • 1,950 citations

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

1996 • 1,496 citations

Cellular Events in the Bronchi in Mild Asthma and after Bronchial Provocation

1989 • 1,158 citations

IL-18: A TH1 -inducing, proinflammatory cytokine and new member of the IL-1 family

1999 • 806 citations

Activation of CD4+ T cells, increased T-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma

1993 • 593 citations

Interleukin-10 regulation in normal subjects and patients with asthma

1996 • 498 citations

Interleukin‐1β, Interleukin‐18, and the Interleukin‐1β Converting Enzyme^a

1998 • 495 citations

IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

1999 • 435 citations

IL-17 Is Produced by Some Proinflammatory Th1/Th0 Cells But Not by Th2 Cells

1999 • 415 citations

The role of IL-13 and its receptor in allergy and inflammatory responses

1998 • 398 citations

IL-18 Is a Potent Coinducer of IL-13 in NK and T Cells: A New Potential Role for IL-18 in Modulating the Immune Response

1999 • 351 citations

Interleukin-17 is Produced by Both Th1 and Th2 Lymphocytes, and Modulates Interferon-γ- and Interleukin-4-Induced Activation of Human Keratinocytes

2000 • 289 citations

Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus

1999 • 286 citations

Interferon-γ-Inducing Factor, a Novel Cytokine, Enhances Fas Ligand-Mediated Cytotoxicity of Murine T Helper 1 Cells

1996 • 277 citations

Interleukin-10 and Transforming Growth Factor- β Promoter Polymorphisms in Allergies and Asthma

1998 • 250 citations

IFN-γ-Inducing Factor (IL-18) Increases Allergic Sensitization, Serum IgE, Th2 Cytokines, and Airway Eosinophilia in a Mouse Model of Allergic Asthma

2000 • 227 citations

Role of pro- and anti-inflammatory cytokines during inflammation: experimental and clinical findings.

1997 • 206 citations

Interleukin-17

1998 • 201 citations

Delayed eosinophil apoptosis in asthma

2000 • 176 citations

Medical Section of the American Lung Association: Guidelines for the Evaluation of Impairment/Disability in Patients with Asthma

1993 • 175 citations

In vivo administration of IL-18 can induce IgE production through Th2 cytokine induction and up-regulation of CD40 ligand (CD154) expression on CD4+ T cells

2000 • 170 citations

Increased interleukin-10 messenger RNA expression in atopic allergy and asthma.

1996 • 158 citations

Expansion of cytokine-producing CD4-CD8- T cells associated with abnormal Fas expression and hypereosinophilia.

1996 • 149 citations

Sensitization to inhaled allergens as a risk factor for asthma and allergic diseases in Chinese population

1997 • 147 citations

Cellular infiltration of the airways in asthma of varying severity.

1996 • 137 citations

Total blood eosinophils, serum eosinophil cationic protein and eosinophil protein X in childhood asthma: relation to disease status and therapy

1993 • 133 citations

Endogenous interleukin‐10 suppresses allergen‐induced airway inflammation and nonspecific airway responsiveness

2000 • 132 citations

Role of interleukin-4 and vascular cell adhesion molecule-1 in selective eosinophil migration into the airways in allergic asthma.

1996 • 123 citations

Characterization of T Cell Subpopulations Involved in the Pathogenesis of Asthma and Allergic Diseases

2000 • 118 citations

Increased interleukin-13 mRNA expression in bronchoalveolar lavage cells of atopic patients with mild asthma after repeated low-dose allergen provocations

2000 • 108 citations

Apoptosis of eosinophils and lymphocytes in allergic inflammation☆☆☆

1999 • 106 citations

Increase in IL-8, IL-10, IL-13, and RANTES mRNA levels (in situ hybridization) in the nasal mucosa after nasal allergen provocation

1999 • 95 citations

Interleukin-18 Enhances Antigen-induced Eosinophil Recruitment into the Mouse Airways

1999 • 90 citations

Interleukin‐12 Induces Sustained Activation of Multiple Host Inflammatory Mediator Systems in Chimpanzees

1999 • 74 citations

Asthma: recent advances

1998 • 68 citations

Synergistic Effects of Interleukin-4 or Interleukin-13 and Tumor Necrosis Factor- α on Eosinophil ActivationIn Vitro

1999 • 67 citations

Pathological changes according to the severity of asthma

1996 • 52 citations

Predictive nomograms for forced expiratory volume, forced vital capacity, and peak expiratory flow rate, in Chinese adults and children

1983 • 48 citations

Cloned Th Cells Confer Eosinophilic Inflammation and Bronchial Hyperresponsiveness

1999 • 17 citations

Aetiology of allergic rhinitis in Hong Kong

1998 • 7 citations

Serum eosinophil cationic protein (ECP) as a mediator of inflammation in acute asthma, during resolution and during the monitoring of stable asthmatic patients treated with inhaled steroids according to a dose reduction schedule

1999 • 7 citations

Cited By (0)

Loading...