Asthma: recent advances

Human Chemokines: An Update

1997 • 2,235 citations

Exposure to House-Dust Mite Allergen (Der pI) and the Development of Asthma in Childhood

1990 • 1,677 citations

The Inverse Association Between Tuberculin Responses and Atopic Disorder

1997 • 1,305 citations

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

1996 • 1,304 citations

Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4

1993 • 972 citations

A genome-wide search for quantitative trait loci underlying asthma

1996 • 797 citations

Increase in asthma: a more toxic environment or a more susceptible population?

1994 • 483 citations

Expression cloning of a human B1 bradykinin receptor.

1994 • 455 citations

Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics.

1997 • 416 citations

The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis.

1995 • 378 citations

Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase.

1991 • 326 citations

Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts.

1997 • 309 citations

DNA antisense therapy for asthma in an animal model

1997 • 261 citations

Interleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness.

1996 • 220 citations

IgE regulates mouse basophil Fc epsilon RI expression in vivo.

1997 • 165 citations

Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma

1996 • 142 citations

Complexity and Redundancy in the Pathogenesis of Asthma: Reassessing the Roles of Mast Cells and T Cells

1997 • 119 citations

Eosinophil granule proteins activate human heart mast cells.

1996 • 110 citations

Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitized airway smooth muscle.

1997 • 97 citations

An immunoglobulin E-dependent recombinant histamine-releasing factor induces interleukin-4 secretion from human basophils.

1996 • 85 citations

Characterization of Platelet-activating Factor Acetylhydrolase in Human Bronchoalveolar Lavage

1997 • 56 citations

In vivo characterization of the anti-inflammatory effect of cyclosporin A on human basophils.

1993 • 49 citations

A newly recognized pathway for the negative regulation of mast cell-dependent hypersensitivity and inflammation mediated by an endogenous cell surface receptor of the gp49 family.

1997 • 33 citations