Endogenous interleukin‐10 suppresses allergen‐induced airway inflammation and nonspecific airway responsiveness

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Predominant T_H2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

1992 • 2,802 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Eosinophilic Inflammation in Asthma

1990 • 2,535 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Anti-inflammatory Actions of Glucocorticoids: Molecular Mechanisms

1998 • 1,516 citations

Cellular Events in the Bronchi in Mild Asthma and after Bronchial Provocation

1989 • 1,158 citations

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses.

1996 • 1,128 citations

Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production.

1993 • 945 citations

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

1996 • 734 citations

IgE Versus IgG4 Production Can Be Differentially Regulated by IL-10

1998 • 565 citations

Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance.

1993 • 526 citations

Inhaled Corticosteroids Increase Interleukin-10 but Reduce Macrophage Inflammatory Protein-1 α , Granulocyte-Macrophage Colony-stimulating Factor, and Interferon- γ Release from Alveolar Macrophages in Asthma

1998 • 345 citations

Interleukin-10 Is a Natural Suppressor of Cytokine Production and Inflammation in a Murine Model of Allergic Bronchopulmonary Aspergillosis

1997 • 324 citations

A Novel T Cell-Regulated Mechanism Modulating Allergen-Induced Airways Hyperreactivity in BALB/c Mice Independently of IL-4 and IL-5

1998 • 291 citations

Interleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice.

1995 • 283 citations

Requirement for γδ T Cells in Allergic Airway Inflammation

1998 • 268 citations

Interleukin-12 inhibits antigen-induced airway hyperresponsiveness in mice.

1996 • 206 citations

Development of airway hyperresponsiveness is dependent on interferon-gamma and independent of eosinophil infiltration.

1997 • 191 citations

IL-10: Evolving concepts☆☆☆★★★

1998 • 167 citations

Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia.

1998 • 142 citations

Cellular infiltration of the airways in asthma of varying severity.

1996 • 137 citations

Modulation by IL-10 of antigen-induced IL-5 generation, and CD4+ T lymphocyte and eosinophil infiltration into the mouse peritoneal cavity.

1996 • 90 citations

Effect of antigen provocation of IL-5 transgenic mice on eosinophil mobilization and bronchial hyperresponsiveness

1996 • 78 citations

Requirement of CD4-positive T cells for cellular recruitment to the lungs of mice in response to a particulate intratracheal antigen.

1991 • 70 citations

Eosinophils are not required to induce airway hyperresponsiveness after nematode infection

1998 • 60 citations

Specificity of Fc receptors of activated T cells. Relation with released immunoglobulin‐binding factor

1975 • 59 citations

Pathological changes according to the severity of asthma

1996 • 52 citations

Role of IL-13 in CD4 T Cell-Dependent IgE Production in Atopy

1997 • 45 citations

Induction of antigen-specific IgE response in murine lymphocytes by IL-10

1995 • 23 citations

Inhibition of Pulmonary Eosinophilia Does Not Necessarily Prevent the Airway Hyperresponsiveness Induced by Sephadex Beads

1998 • 16 citations