Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.

1991 • 1,880 citations

Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

1990 • 1,155 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

1991 • 752 citations

Structure and Function of Leukocyte Integrins

1990 • 620 citations

Expression of Interleukin-10 Activity by Epstein-Barr Virus Protein BCRF1

1990 • 539 citations

Interleukin 10: a novel stimulatory factor for mast cells and their progenitors.

1991 • 514 citations

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

1988 • 509 citations

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses.

1987 • 490 citations

Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells.

1990 • 487 citations

Isolation and characterization of antigen-la complexes involved in T cell recognition

1986 • 470 citations

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

1990 • 468 citations

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

1990 • 445 citations

Interleukin-4 (IL-4) inhibits secretion of IL-1 beta, tumor necrosis factor alpha, and IL-6 by human monocytes

1990 • 438 citations

A new murine CD4+ T cell subset with an unrestricted cytokine profile.

1989 • 374 citations

IL-10, a novel growth cofactor for mature and immature T cells.

1990 • 371 citations

Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10

1990 • 347 citations

Roles of Adhesion Molecules in T‐Cell Recognition: Fundamental Similarities between Four Integrins on Resting Human T Cells (LFA‐1, VLA‐4, VLA‐5, VLA‐6) in Expression, Binding, and Costimulation

1990 • 322 citations

Antigen Presentation Pathways to Class I and Class II MHC‐Restricted T Lymphocytes

1987 • 322 citations

Selection of a human T helper type 1-like T cell subset by mycobacteria.

1991 • 281 citations

Interferon-beta 2/interleukin 6 is a co-stimulant for human T lymphocytes.

1988 • 125 citations

A mouse monoclonal antibody detecting a DR-related MT2-like specificity: Serology and biochemistry

1984 • 97 citations

Specific killing of cytotoxic T cells and antigen-presenting cells by CD4+ cytotoxic T cell clones. A novel potentially immunoregulatory T-T cell interaction in man.

1990 • 95 citations

Functional and ultrastructural evidence for intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing.

1990 • 81 citations

Functional heterogeneity among herpes simplex virus-specific human CD4+ T cells.

1991 • 71 citations

Lack of detectable endocytosis of B lymphocyte MHC class II antigens using an antibody-independent technique.

1990 • 66 citations

Increase of surface Ia-like antigen expression on human monocytes independent of antigenic stimuli.

1981 • 58 citations

T cell clones which share T cell receptor epitopes differ in phenotype, function and specificity

1986 • 28 citations

A centrifugal elutriation system of separating small numbers of cells

1984 • 26 citations

The Interaction between Protein‐Derived Immunogenic Peptides and Ia

1987 • 6 citations