IL-17 Is Produced by Some Proinflammatory Th1/Th0 Cells But Not by Th2 Cells

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS

1996 • 2,527 citations

Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes

1998 • 1,574 citations

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

1996 • 1,496 citations

Insulin-Dependent Diabetes Mellitus

1996 • 1,171 citations

Human TH1 and TH2 subsets: doubt no more

1991 • 1,103 citations

Selective Expression of the Eotaxin Receptor CCR3 by Human T Helper 2 Cells

1997 • 1,073 citations

Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells

1997 • 1,022 citations

Human IL-17: a novel cytokine derived from T cells.

1995 • 1,014 citations

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

1995 • 991 citations

Selective Expression of an Interleukin-12 Receptor Component by Human T Helper 1 Cells

1997 • 783 citations

How important are t cells in chronic rheumatoid synovitis?

1990 • 553 citations

Enhancing Effect of IL-17 on IL-1-Induced IL-6 and Leukemia Inhibitory Factor Production by Rheumatoid Arthritis Synoviocytes and Its Regulation by Th2 Cytokines

1998 • 451 citations

Role of cytokines in determining T-lymphocyte function

1994 • 396 citations

Divergent T-cell cytokine patterns in inflammatory arthritis.

1994 • 388 citations

Strategies of Anti‐Cytokine Monoclonal Antibody Development: Immunoassay of IL‐10 and IL‐5 in Clinical Samples

1992 • 384 citations

Cytokine production at the site of disease in human tuberculosis

1993 • 379 citations

Shift toward T lymphocytes with a T helper 1 cytokine‐secretion profile in the joints of patients with rheumatoid arthritis

1996 • 299 citations

Th1/Th2 cytokine balance in arthritis

1997 • 259 citations

Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis.

1988 • 249 citations

T Cells Cloned from Human Rheumatoid Synovial Membrane Functionally Represent the Th 1 Subset

1992 • 177 citations

Cytokines in chronic inflammatory arthritis. IV. Granulocyte/macrophage colony-stimulating factor-mediated induction of class II MHC antigen on human monocytes: a possible role in rheumatoid arthritis.

1989 • 166 citations

Natural killer cell stimulatory factor (NKSF) or interleukin-12 is a key regulator of immune response and inflammation

1992 • 164 citations

Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-gamma.

1988 • 147 citations

Rheumatoid Inflammatory T‐Cell Clones express mostly Th1 but also Th2 and Mixed (Th0‐Like) Cytokine Patterns

1993 • 132 citations

High level of interleukin-10 production by the activated t cell population within the rheumatoid synovial membrane

1995 • 121 citations

Peptide recognition, T cell receptor usage and HLA restriction elements of human heat‐shock protein (hsp) 60 and mycobacterial 65‐kDa hsp‐reactive T cell clones from rheumatoid synovial fluid

1992 • 118 citations

Cellular Basis for Rheumatoid Inflammation

1991 • 94 citations

Tγδ Cells in Juvenile Rheumatoid Arthritis and Rheumatoid Arthritis

1990 • 68 citations

Manipulation of the Th1/Th2 Cell Balance: An Approach to Treat Human Autoimmune Diseases?

1996 • 63 citations

The role of T-Iymphocytes in rheumatoid arthritis

1995 • 62 citations

Expression of CD45RB and CD27 identifies subsets of CD4+ memory T cells with different capacities to induce B cell differentiation.

1995 • 61 citations

Immune Responses to 6 and 30‐kDa Mycobacterial Antigens in Rheumatoid Patients, and Vβ Usage by Specific Synovial T‐Cell Lines and Fresh T Cells

1991 • 43 citations

Impact of antigen-presenting cells on cytokine profiles of human Th clones established after stimulation with Mycobacterium tuberculosis antigens

1995 • 15 citations