Exocytotic Insertion of TRPC6 Channel into the Plasma Membrane upon Gq Protein-coupled Receptor Activation

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

The versatility and universality of calcium signalling

2000 • 5,407 citations

Small GTP-Binding Proteins

2001 • 2,449 citations

Calcium - a life and death signal

1998 • 2,040 citations

THE CAVEOLAE MEMBRANE SYSTEM

1998 • 1,947 citations

Depletion of intracellular calcium stores activates a calcium current in mast cells

1992 • 1,748 citations

Capacitative calcium entry revisited

1990 • 1,499 citations

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

1999 • 1,456 citations

Membrane Fusion and Exocytosis

1999 • 1,252 citations

Capacitative calcium entry

1995 • 1,112 citations

The trp ion channel family

2001 • 1,108 citations

Caveolae: From Cell Biology to Animal Physiology

2002 • 977 citations

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

1993 • 892 citations

TRPC1 and TRPC5 Form a Novel Cation Channel in Mammalian Brain

2001 • 737 citations

Subunit composition of mammalian transient receptor potential channels in living cells

2002 • 729 citations

trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry

1996 • 688 citations

Functional interaction between InsP3 receptors and store-operated Htrp3 channels

1998 • 620 citations

TRP Channel Proteins and Signal Transduction

2002 • 571 citations

Molecular and Functional Characterization of a Novel Mouse Transient Receptor Potential Protein Homologue TRP7

1999 • 451 citations

Store-Operated Ca2+ Entry

1999 • 433 citations

Receptor-mediated Regulation of the Nonselective Cation Channels TRPC4 and TRPC5

2000 • 422 citations

Assembly of Trp1 in a Signaling Complex Associated with Caveolin-Scaffolding Lipid Raft Domains

2000 • 403 citations

Cloning and Functional Expression of a Human Ca2+-Permeable Cation Channel Activated by Calcium Store Depletion

1996 • 391 citations

Regulation of receptor-mediated endocytosis by Rho and Rac

1996 • 386 citations

Modulation of Ca ²⁺ entry by polypeptides of the inositol 1,4,5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in store depletion-activated Ca ²⁺ entry

1999 • 377 citations

Cloning and Expression of a Novel Mammalian Homolog ofDrosophila Transient Receptor Potential (Trp) Involved in Calcium Entry Secondary to Activation of Receptors Coupled by the Gq Class of G Protein

1997 • 337 citations

Selective Association of TRPC Channel Subunits in Rat Brain Synaptosomes

2002 • 314 citations

Identification of Common Binding Sites for Calmodulin and Inositol 1,4,5-Trisphosphate Receptors on the Carboxyl Termini of Trp Channels

2001 • 296 citations

A GTP-dependent step in the activation mechanism of capacitative calcium influx.

1993 • 283 citations

Trp1, a Candidate Protein for the Store-operated Ca2+Influx Mechanism in Salivary Gland Cells

2000 • 276 citations

Rho Proteins: Linking Signaling with Membrane Trafficking

2001 • 274 citations

The N-Terminal Domain of the IP3 Receptor Gates Store-Operated hTrp3 Channels

1999 • 268 citations

Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger

1999 • 260 citations

Association of Mammalian Trp4 and Phospholipase C Isozymes with a PDZ Domain-containing Protein, NHERF

2000 • 250 citations

Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain

2001 • 219 citations

RhoA Interaction with Inositol 1,4,5-Trisphosphate Receptor and Transient Receptor Potential Channel-1 Regulates Ca2+ Entry

2003 • 218 citations

Calcium Oscillation Linked to Pacemaking of Interstitial Cells of Cajal

2002 • 201 citations

A Role for the Actin Cytoskeleton in the Initiation and Maintenance of Store-mediated Calcium Entry in Human Platelets

2000 • 191 citations

Identification of mouse trp homologs and lipid rafts from spermatogenic cells and sperm

2001 • 174 citations

Regulated exocytosis and SNARE function (Review)

2003 • 173 citations

Coupling between inositol 1,4,5-trisphosphate receptors and human transient receptor potential channel 1 when intracellular Ca2+ stores are depleted

2000 • 165 citations

Calmodulin Regulates Ca2+-Dependent Feedback Inhibition of Store-Operated Ca2+ Influx by Interaction with a Site in the C Terminus of TrpC1

2002 • 148 citations

Stabilization of Cortical Actin Induces Internalization of Transient Receptor Potential 3 (Trp3)-associated Caveolar Ca2+ Signaling Complex and Loss of Ca2+ Influx without Disruption of Trp3-Inositol Trisphosphate Receptor Association

2001 • 144 citations

Intimate Plasma Membrane–ER Interactions Underlie Capacitative Calcium Entry: “Kissin' Cousins”

1999 • 134 citations

Cell biology of caveolae and caveolin

2001 • 133 citations

A C. elegans Sperm TRP Protein Required for Sperm-Egg Interactions during Fertilization

2003 • 133 citations

The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways.

1996 • 130 citations

A Molecular Sensor Detects Signal Transduction from Caveolae in Living Cells

2002 • 122 citations

Membrane Tethering and Fusion in the Secretory and Endocytic Pathways

2000 • 116 citations

Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes.

1995 • 110 citations

Functional expression of TrpC1: a human homologue of the Drosophila Trp channel

1998 • 109 citations

20-Hydroxyeicosatetraenoic Acid (20-HETE) Activates Mouse TRPC6 Channels Expressed in HEK293 Cells

2003 • 96 citations

Induction of Exocytosis from Permeabilized Mast Cells by the Guanosine Triphosphatases Rac and Cdc42

1998 • 89 citations

Ca2+-calmodulin regulates receptor-operated Ca2+ entry activity of TRPC6 in HEK-293 cells

2002 • 86 citations

The transient receptor potential, TRP4, cation channel is a novel member of the family of calmodulin binding proteins

2001 • 76 citations

Mechanism of capacitative Ca2+ entry (CCE): interaction between IP3 receptor and TRP links the internal calcium storage compartment to plasma membrane CCE channels.

2000 • 72 citations

Store-operated Ca2+ Current in Prostate Cancer Epithelial Cells

2003 • 64 citations

On the characterisation of the mechanism underlying passive activation of the Ca²⁺ release‐activated Ca²⁺ current I_CRAC in rat basophilic leukaemia cells

1999 • 39 citations

Evidence for a vesicle-mediated maintenance of store-operated calcium channels in a human embryonic kidney cell line

2000 • 31 citations

Thapsigargin activates univalent- and bivalent-cation entry in human neutrophils by a SK&F I3 96365- and Gd3+-sensitive pathway and is a partial secretagogue: involvement of pertussis-toxin-sensitive G-proteins and protein phosphatases 1/2A and 2B in the signal-transduction pathway

1996 • 27 citations

RhoA-sensitive trafficking of muscarinic acetylcholine receptors.

1999 • 25 citations

Depletion and refilling of intracellular calcium pools in bovine chromaffin cells

1994 • 8 citations