TRPC1 and TRPC5 Form a Novel Cation Channel in Mammalian Brain

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Ionic channels of excitable membranes

1985 • 7,199 citations

Ionic Channels of Excitable Membranes

1985 • 3,014 citations

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

1999 • 1,456 citations

A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle

1987 • 786 citations

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors

1992 • 732 citations

trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry

1996 • 688 citations

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

1988 • 669 citations

TRPC1, a human homolog of a Drosophila store-operated channel.

1995 • 623 citations

Functional interaction between InsP3 receptors and store-operated Htrp3 channels

1998 • 620 citations

Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging

1998 • 575 citations

From worm to man: three subfamilies of TRP channels

2000 • 490 citations

Molecular and Functional Characterization of a Novel Mouse Transient Receptor Potential Protein Homologue TRP7

1999 • 451 citations

TRP2: A candidate transduction channel for mammalian pheromone sensory signaling

1999 • 440 citations

Receptor-mediated Regulation of the Nonselective Cation Channels TRPC4 and TRPC5

2000 • 422 citations

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL

1999 • 400 citations

Cloning and Functional Expression of a Human Ca2+-Permeable Cation Channel Activated by Calcium Store Depletion

1996 • 391 citations

The Drosophila Light-Activated Conductance Is Composed of the Two Channels TRP and TRPL

1996 • 368 citations

Molecular cloning of a widely expressed human homologue for the Drosophila trp gene

1995 • 351 citations

Activation of a TRPC3-Dependent Cation Current through the Neurotrophin BDNF

1999 • 343 citations

Cloning and Expression of a Novel Mammalian Homolog ofDrosophila Transient Receptor Potential (Trp) Involved in Calcium Entry Secondary to Activation of Receptors Coupled by the Gq Class of G Protein

1997 • 337 citations

Permeation and Gating Properties of the Novel Epithelial Ca2+ Channel

2000 • 318 citations

Mammalian ionotropic glutamate receptors

1993 • 312 citations

Coassembly of TRP and TRPL Produces a Distinct Store-Operated Conductance

1997 • 310 citations

A novel capacitative calcium entry channel expressed in excitable cells

1998 • 308 citations

Coassembly of Trp1 and Trp3 Proteins Generates Diacylglycerol- and Ca2+-sensitive Cation Channels

2000 • 299 citations

Nicotinic receptor function: new perspectives from knockout mice

2000 • 297 citations

Molecular Cloning and Functional Characterization of a Novel Receptor-activated TRP Ca2+ Channel from Mouse Brain

1998 • 294 citations

Visual Transduction in Drosophila

1999 • 288 citations

A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL.

1996 • 286 citations

Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca ²⁺ entry channel

1999 • 278 citations

Trp1, a Candidate Protein for the Store-operated Ca2+Influx Mechanism in Salivary Gland Cells

2000 • 276 citations

Neurotransmitter action: Opening of ligand-gated ion channels

1993 • 267 citations

Axonal Membrane Proteins Are Transported in Distinct Carriers: A Two-Color Video Microscopy Study in Cultured Hippocampal Neurons

2000 • 264 citations

Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization

1993 • 262 citations

The Role of Selective Transport in Neuronal Protein Sorting

2000 • 261 citations

Expression of TRPC3 in Chinese Hamster Ovary Cells Results in Calcium-activated Cation Currents Not Related to Store Depletion

1997 • 259 citations

Association of Mammalian Trp4 and Phospholipase C Isozymes with a PDZ Domain-containing Protein, NHERF

2000 • 250 citations

The Store-Operated Calcium Current ICRAC: Nonlinear Activation by InsP3 and Dissociation from Calcium Release

1997 • 231 citations

Activation of recombinant trp by thapsigargin in Sf9 insect cells

1994 • 226 citations

InsP3 Receptor Is Essential for Growth and Differentiation but Not for Vision in Drosophila

1997 • 222 citations

Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues

1995 • 193 citations

The biology of vision of Drosophila.

1996 • 192 citations

Muscarinic Activation of a Voltage-Dependent Cation Nonselective Current in Rat Association Cortex

1996 • 192 citations

Paracrine neurotransmission in the CNS: involvement of 5-HT

1999 • 190 citations

In Vivo Analysis of the Drosophila Light-Sensitive Channels, TRP and TRPL

1997 • 189 citations

TRP4 (CCE1) Protein Is Part of Native Calcium Release-activated Ca2+-like Channels in Adrenal Cells

2000 • 186 citations

Sense and specificity: a molecular identity for nociceptors

1999 • 181 citations

A Long-Lasting Calcium-Activated Nonselective Cationic Current Is Generated by Synaptic Stimulation or Exogenous Activation of Group I Metabotropic Glutamate Receptors in CA1 Pyramidal Neurons

1997 • 174 citations

Trp proteins form store‐operated cation channels in human vascular endothelial cells

1998 • 162 citations

Gating of Store-Operated Channels by Conformational Coupling to Ryanodine Receptors

2000 • 155 citations

Differential Expression of MammalianTRPHomologues across Tissues and Cell Lines

1997 • 153 citations

TRPγ, a Drosophila TRP–Related Subunit, Forms a Regulated Cation Channel with TRPL

2000 • 151 citations

Molecular biology of glutamate receptors

1994 • 141 citations

Normal Phototransduction in Drosophila Photoreceptors Lacking an InsP3 Receptor Gene

2000 • 132 citations

Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons

1994 • 113 citations

Coexpression of Drosophila TRP and TRP-like proteins in Xenopus oocytes reconstitutes capacitative Ca ²⁺ entry

1996 • 105 citations

Activity and Synaptic Receptor Targeting

1998 • 95 citations

GIRK1 immunoreactivity is present predominantly in dendrites, dendritic spines, and somata in the CA1 region of the hippocampus

1997 • 95 citations

Calcium-activated non-selective channels in the nervous system

1994 • 93 citations

Evidence for Direct Physical Association between a K⁺Channel (Kir6.2) and an ATP-Binding Cassette Protein (SUR1) Which Affects Cellular Distribution and Kinetic Behavior of an ATP-Sensitive K⁺ Channel

1998 • 81 citations

Molecular cloning and characterization of rat trp homologues from brain

1999 • 76 citations

Differential distribution of TRP Ca2+ channel isoforms in mouse brain.

1998 • 74 citations

Muscarinic receptors regulate two different calcium‐dependent non‐selective cation currents in rat prefrontal cortex

1999 • 62 citations

Concomitant and hormonally regulated expression of trp genes in bovine aortic endothelial cells

1997 • 61 citations

Calmodulin Regulation of Calcium Stores in Phototransduction of Drosophila

1997 • 57 citations

A novel voltage‐dependent cation current in rat neocortical neurones.

1994 • 52 citations

Calcium‐induced inactivation of NMDA receptor‐channels evolves independently of run‐down in cultured rat brain neurones.

1996 • 50 citations

Receptor targeting and heterogeneity at interneuronal nicotinic cholinergic synapses in vivo

2000 • 44 citations

Functional diversity of muscarinic receptor subtypes in cellular signal transduction and growth.

1989 • 42 citations

Expression and Characterization of atrplHomolog from Rat

1997 • 36 citations

Calmodulin regulation of light adaptation and store-operated dark current in Drosophila photoreceptors

1997 • 35 citations

Expression of human TRPC genes in the megakaryocytic cell lines MEG01, DAMI and HEL

1997 • 30 citations

Chapter 6 Molecular organization of cerebellar glutamate synapses

1997 • 18 citations

Ligand-gated channel: postsynaptic receptors and drug targets.

1999 • 17 citations

Divalent cation permeability and blockade of Ca²⁺‐permeant non‐selective cation channels in rat adrenal zona glomerulosa cells

1999 • 9 citations