Rab24 Is an Atypical Member of the Rab GTPase Family

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

All ras proteins are polyisoprenylated but only some are palmitoylated

1989 • 1,806 citations

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

1992 • 1,342 citations

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1989 • 1,244 citations

FUNCTION AND REGULATION OF RAS

1993 • 1,161 citations

The diversity of Rab proteins in vesicle transport

1997 • 762 citations

Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles.

1995 • 694 citations

Protein Prenyltransferases

1996 • 693 citations

The ras protein family: evolutionary tree and role of conserved amino acids

1991 • 573 citations

Biological and biochemical properties of human rasH genes mutated at codon 61

1986 • 538 citations

Rho GTPases

1998 • 534 citations

GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex.

1992 • 497 citations

GTPases: Multifunctional Molecular Switches Regulating Vesicular Traffic

1994 • 411 citations

Three-dimensional structures of H-ras p21 mutants: Molecular basis for their inability to function as signal switch molecules

1990 • 395 citations

Hypervariable C-termmal domain of rab proteins acts as a targeting signal

1991 • 394 citations

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys.

1992 • 323 citations

Rab GTPases, Directors of Vesicle Docking

1998 • 322 citations

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

1993 • 322 citations

GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

1996 • 322 citations

Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange

1994 • 313 citations

Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B).

1991 • 291 citations

Rab proteins and the road maps for intracellular transport

1993 • 276 citations

Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor.

1990 • 268 citations

Identification of a Novel Human Rho Protein with Unusual Properties: GTPase Deficiency and In Vivo Farnesylation

1996 • 265 citations

Rab GDP Dissociation Inhibitor: Putting Rab GTPases in the Right Place

1995 • 240 citations

A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments.

1994 • 226 citations

Evidence for the involvement of Rab3A in Ca(2+)-dependent exocytosis from adrenal chromaffin cells.

1994 • 224 citations

Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI

1997 • 218 citations

Structure and mutational analysis of Rab GDP-dissociation inhibitor

1996 • 173 citations

Rab GDI: a solubilizing and recycling factor for rab9 protein.

1993 • 152 citations

Rab3C is a synaptic vesicle protein that dissociates from synaptic vesicles after stimulation of exocytosis

1994 • 151 citations

Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag.

1993 • 148 citations

Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily

1993 • 146 citations

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A.

1994 • 139 citations

The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach

1992 • 120 citations

Throttles and Dampers: Controlling the Engine of Membrane Fusion

1997 • 107 citations

Mechanism of Digeranylgeranylation of Rab Proteins

1996 • 95 citations

cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase

1993 • 94 citations

Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing factor

1993 • 92 citations

A model system for studying membrane biogenesis: overexpression of cytochrome B5 in yeast results in marked proliferation of the intracellular membrane*

1993 • 90 citations

Mechanism of Rab Geranylgeranylation: Formation of the Catalytic Ternary Complex

1998 • 87 citations

The geranylgeranyl moiety but not the methyl moiety of the smg-25A/rab3A protein is essential for the interactions with membrane and its inhibitory GDP/GTP exchange protein.

1992 • 86 citations

Distinct Functional Properties of Rab3A and Rab3B in PC12 Neuroendocrine Cells

1996 • 77 citations

Association of Rab1B with GDP-dissociation Inhibitor (GDI) Is Required for Recycling but Not Initial Membrane Targeting of the Rab Protein

1996 • 70 citations

Post-translational processing of Schizosaccharomyces pombe YPT proteins.

1992 • 68 citations

Determination of structural requirements for the interaction of Rab6 with RabGDI and Rab geranylgeranyltransferase.

1994 • 65 citations

The Ras-related GTP-binding Protein, Rab1B, Regulates Early Steps in Exocytic Transport and Processing of β-Amyloid Precursor Protein

1995 • 65 citations

Nucleotide Dependence of Rab Geranylgeranylation

1996 • 60 citations

Biochemical and Functional Characterization of a Recombinant GTPase, Rab5, and Two of Its Mutants

1995 • 54 citations

Differential intracellular localizations of GDP dissociation inhibitor isoforms. Insulin-dependent redistribution of GDP dissociation inhibitor-2 in 3T3-L1 adipocytes.

1994 • 54 citations

Prenylation of Rab8 GTPase by type I and type II geranylgeranyl transferases

1998 • 47 citations

Interaction between Cdc42Hs and RhoGDI Is Mediated through the Rho Insert Region

1997 • 46 citations

Guidebook to the small GTPases

1996 • 41 citations

The Putative “Switch 2” Domain of the Ras-related GTPase, Rab1B, Plays an Essential Role in the Interaction with Rab Escort Protein

1998 • 29 citations

Isoprenoid requirement for intracellular transport and processing of murine leukemia virus envelope protein.

1992 • 26 citations

The expression pattern of rab3D in the developing rat exocrine pancreas coincides with the acquisition of regulated exocytosis.

1996 • 23 citations

Expression of Rab3A GTPase and other synaptic proteins is induced in differentiated NT2N neurons

1998 • 18 citations

Chapter 14 Expression of Foreign Proteins in a Human Neuronal System

1994 • 17 citations

Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells

1996 • 15 citations

Cholesterol and phospholipids in cultured skin fibroblasts from patients with dystonia

1984 • 8 citations

Deleted Work

1955 • 0 citations