Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation

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Batf3 Deficiency Reveals a Critical Role for CD8α ⁺ Dendritic Cells in Cytotoxic T Cell Immunity

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CELL BIOLOGY OF ANTIGEN PROCESSING IN VITRO AND IN VIVO

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A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on MHC Class I Molecules

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NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

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Cross‐presentation, dendritic cell subsets, and the generation of immunity to cellular antigens

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Phagosomes are competent organelles for antigen cross-presentation

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Phagocytic processing of bacterial antigens for class I MHC presentation to T cells

1993 • 625 citations

Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation

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Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells.

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Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells

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ADP-Ribosylation Factor 6 Regulates a Novel Plasma Membrane Recycling Pathway

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Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

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Cross‐presentation: underlying mechanisms and role in immune surveillance

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Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens

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Important Role of Cathepsin S in Generating Peptides for TAP-Independent MHC Class I Crosspresentation In Vivo

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Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I

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Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells

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Both Dendritic Cells and Macrophages Can Stimulate Naive CD8 T Cells In Vivo to Proliferate, Develop Effector Function, and Differentiate into Memory Cells

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An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope

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Analysis of Protease Activity in Live Antigen-presenting Cells Shows Regulation of the Phagosomal Proteolytic Contents During Dendritic Cell Activation

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The Phagosomal Proteome in Interferon-γ-Activated Macrophages

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The cell biology of cross‐presentation and the role of dendritic cell subsets

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Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation.

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Hepatitis B virus small surface antigen particles are processed in a novel endosomal pathway for major histocompatibility complex class I‐restricted epitope presentation

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Binding of Lysozyme to Phospholipid Bilayers: Evidence for Protein Aggregation upon Membrane Association

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Macrophage Activation Downregulates the Degradative Capacity of the Phagosome

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Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases

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Early endosomes and a late endocytic compartment generate different peptide-class II MHC complexes via distinct processing mechanisms.

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Leishmania Antigens Are Presented to CD8+ T Cells by a Transporter Associated with Antigen Processing-Independent Pathway In Vitro and In Vivo

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Kaposi's Sarcoma-Associated Herpesvirus K3 Utilizes the Ubiquitin-Proteasome System in Routing Class I Major Histocompatibility Complexes to Late Endocytic Compartments

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The many roads to cross-presentation

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T Cells Distinguish MHC-Peptide Complexes Formed in Separate Vesicles and Edited by H2-DM

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Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells

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Quantifying Cathepsin S Activity in Antigen Presenting Cells Using a Novel Specific Substrate

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Selective involvement of proteasomes and cysteine proteases in MHC class I antigen presentation.

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Tapasin−/− and TAP1−/− Macrophages Are Deficient in Vacuolar Alternate Class I MHC (MHC-I) Processing due to Decreased MHC-I Stability at Phagolysosomal pH

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Bacterial Proteins Can Be Processed by Macrophages in a Transporter Associated with Antigen Processing-Independent, Cysteine Protease-Dependent Manner for Presentation by MHC Class I Molecules

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Conformational isomers of a peptide–class II major histocompatibility complex

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Chondroitin sulfate is involved in lysosomal transport of lysozyme in U937 cells

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Activation of CXCR4 Triggers Ubiquitination and Down-regulation of Major Histocompatibility Complex Class I (MHC-I) on Epithelioid Carcinoma HeLa Cells

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Chemical Identification of a Low Abundance Lysozyme Peptide Family Bound to I-Ak Histocompatibility Molecules

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