Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells

Dendritic cells and the control of immunity

1998 • 14,345 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 • 1,601 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

MECHANISMS OF MHC CLASS I–RESTRICTED ANTIGEN PROCESSING

1998 • 1,017 citations

Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay.

1976 • 951 citations

Fcγ Receptor–mediated Induction of Dendritic Cell Maturation and Major Histocompatibility Complex Class I–restricted Antigen Presentation after Immune Complex Internalization

1999 • 898 citations

A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on MHC Class I Molecules

1995 • 882 citations

Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

1997 • 860 citations

Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules.

1997 • 837 citations

CAPTURE AND PROCESSING OF EXOGENOUS ANTIGENS FOR PRESENTATION ON MHC MOLECULES

1997 • 779 citations

Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages.

1993 • 592 citations

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

1999 • 586 citations

Lysosomes Behave as Ca2+-regulated Exocytic Vesicles in Fibroblasts and Epithelial Cells

1997 • 520 citations

Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages

1995 • 416 citations

LacZ inducible, antigen/MHC-specific T cell hybrids

1994 • 377 citations

Constitutive macropinocytosis allows TAP‐dependent major histocompatibility compex class I presentation of exogenous soluble antigen by bone marrow‐derived dendritic cells

1997 • 351 citations

Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis.

1995 • 300 citations

Mechanisms of Exogenous Antigen Presentation by MHC Class I Molecules in Vitro and in Vivo: Implications for Generating CD8+ T Cell Responses to Infectious Agents, Tumors, Transplants, and Vaccines

1999 • 293 citations

Mutant Rab7 Causes the Accumulation of Cathepsin D and Cation-independent Mannose 6–Phosphate Receptor in an Early Endocytic Compartment

1998 • 265 citations

Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells

1998 • 262 citations

Cross-presentation: a general mechanism for CTL immunity and tolerance

1998 • 253 citations

In Vivo Cross-Priming of MHC Class I–Restricted Antigens Requires the TAP Transporter

1996 • 225 citations

Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins.

1987 • 197 citations

Endogenous generation and presentation of the ovalbumin peptide/Kb complex to T cells.

1993 • 185 citations

Dendritic cells process exogenous viral proteins and virus‐like particles for class I presentation to CD8⁺ cytotoxic T lymphocytes

1996 • 149 citations

Processing and Presentation of Endocytically Acquired Protein Antigens by MHC Class II and Class I Molecules

1996 • 99 citations

Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells

1998 • 82 citations

Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages.

1996 • 72 citations

The efficiency of antigen delivery from macrophage phagosomes into cytoplasm for MHC class I-restricted antigen presentation

1997 • 42 citations

Endocytosis of antigen, anti-idiotype, and anti-immunoglobulin antibodies and receptor re-expression by murine B cells.

1989 • 30 citations