Hzf Determines Cell Survival upon Genotoxic Stress by Modulating p53 Transactivation

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Surfing the p53 network

2000 • 6,487 citations

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1995 • 4,043 citations

Live or let die: the cell's response to p53

2002 • 3,138 citations

Requirement for p53 and p21 to Sustain G ₂ Arrest After DNA Damage

1998 • 2,784 citations

PUMA, a Novel Proapoptotic Gene, Is Induced by p53

2001 • 2,226 citations

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

2000 • 2,064 citations

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

1998 • 2,034 citations

The p53 pathway: positive and negative feedback loops

2005 • 1,899 citations

The p53-mdm-2 autoregulatory feedback loop.

1993 • 1,795 citations

p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa

2003 • 1,298 citations

Is a p53-Regulated Inhibitor of G2/M Progression

1997 • 1,238 citations

Identification of p53 as a Sequence-Specific DNA-Binding Protein

1991 • 1,109 citations

Regulation of the specific DNA binding function of p53

1992 • 914 citations

p53 Ubiquitination: Mdm2 and Beyond

2006 • 865 citations

Role ofBAXin the Apoptotic Response to Anticancer Agents

2000 • 854 citations

Chk2/hCds1 functions as a DNA damage checkpoint in G₁by stabilizing p53

2000 • 781 citations

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1996 • 746 citations

The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage

2003 • 718 citations

Pirh2, a p53-Induced Ubiquitin-Protein Ligase, Promotes p53 Degradation

2003 • 708 citations

Acetylation of the p53 DNA-Binding Domain Regulates Apoptosis Induction

2006 • 698 citations

The ubiquitin ligase COP1 is a critical negative regulator of p53

2004 • 693 citations

Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis

2006 • 687 citations

The complexity of p53 stabilization and activation

2006 • 670 citations

ASPP Proteins Specifically Stimulate the Apoptotic Function of p53

2001 • 656 citations

SUMO-1 modification activates the transcriptional response of p53

1999 • 627 citations

Transcriptional regulation by p53: one protein, many possibilities

2006 • 488 citations

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

1999 • 449 citations

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

2002 • 412 citations

PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family

2000 • 397 citations

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response

2002 • 381 citations

Pidd, a new death-domain–containing protein, is induced by p53 and promotes apoptosis

2000 • 349 citations

Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

1995 • 334 citations

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant.

1996 • 299 citations

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72–polymorphic p53

2006 • 257 citations

Identification of mutations in p53 that affect its binding to SV40 large T antigen by using the yeast two‐hybrid system

1993 • 230 citations

p53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosis

2002 • 215 citations

Use of the two-hybrid system to identify the domain of p53 involved in oligomerization.

1993 • 182 citations

p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop

2003 • 179 citations

ASPPs and cancer

2006 • 132 citations

A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes

2002 • 131 citations

A temperature-sensitive mutant of human p53.

1994 • 128 citations

Some p53-binding proteins that can function as arbiters of life and death

2006 • 91 citations

Zinc Finger Protein, Hzf, Is Required for Megakaryocyte Development and Hemostasis

2002 • 39 citations

Hzf, a p53-Responsive Gene, Regulates Maintenance of the G₂ Phase Checkpoint Induced by DNA Damage

2005 • 34 citations

Gene trapping of two novel genes, Hzf and Hhl , expressed in hematopoietic cells

2000 • 29 citations

Erratum: ASPP and cancer

2006 • 18 citations

RZF, a zinc-finger protein in the photoreceptors of human retina

2004 • 15 citations