p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

Cell Signaling by Receptor Tyrosine Kinases

2010 • 7,477 citations

Surfing the p53 network

2000 • 6,487 citations

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

1997 • 4,870 citations

Cell Signaling by Receptor Tyrosine Kinases

2000 • 3,570 citations

A simplified system for generating recombinant adenoviruses

1998 • 3,179 citations

Signaling—2000 and Beyond

2000 • 2,544 citations

p53: puzzle and paradigm.

1996 • 2,363 citations

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

2000 • 2,064 citations

The Discoidin Domain Receptor Tyrosine Kinases Are Activated by Collagen

1997 • 956 citations

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1998 • 912 citations

p53

2000 • 785 citations

Myc suppression of the p21Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

2002 • 676 citations

The ARF/p53 pathway

2000 • 647 citations

An Orphan Receptor Tyrosine Kinase Family Whose Members Serve as Nonintegrin Collagen Receptors

1997 • 510 citations

Opposing Effects of Ras on p53

2000 • 361 citations

Pidd, a new death-domain–containing protein, is induced by p53 and promotes apoptosis

2000 • 349 citations

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

1994 • 322 citations

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53

1997 • 295 citations

Discoidin Domain Receptor 1 Tyrosine Kinase Has an Essential Role in Mammary Gland Development

2001 • 294 citations

The p53 and Mdm2 families in cancer

2002 • 281 citations

Oncogenic ras and p53 Cooperate To Induce Cellular Senescence

2002 • 280 citations

Discoidin domain receptors: structural relations and functional implications

1999 • 267 citations

Analysis of the transcriptional program induced by Raf in epithelial cells

2001 • 255 citations

Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer.

1995 • 245 citations

The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors

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Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

2001 • 210 citations

Discoidin I is implicated in cell-substratum attachment and ordered cell migration of dictyostelium discoideum and resembles fibronectin

1984 • 184 citations

A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain.

1993 • 177 citations

Heparin-binding EGF-like growth factor

1997 • 172 citations

Receptor Tyrosine Kinases

2000 • 165 citations

Discoidin Domain Receptor 1 Is Activated Independently of β1 Integrin

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Regulation of Raf-1 and Raf-1 Mutants by Ras-Dependent and Ras-Independent Mechanisms In Vitro

1995 • 140 citations

Loss of Transgelin in Breast and Colon Tumors and in RIE-1 Cells by Ras Deregulation of Gene Expression through Raf-independent Pathways

2002 • 137 citations

p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades

2001 • 127 citations

Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53

2000 • 106 citations

Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion

2000 • 103 citations

Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues.

1993 • 94 citations

Expression patterns of the novel receptor-like tyrosine kinase, DDR, in human breast tumours.

1995 • 94 citations

Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons

2000 • 89 citations

Direct Binding and Activation of Receptor Tyrosine Kinases by Collagen

1997 • 84 citations

Isolation and characterization of an epithelial-specific receptor tyrosine kinase from an ovarian cancer cell line.

1994 • 72 citations

NEP: a novel receptor-like tyrosine kinase expressed in proliferating neuroepithelia.

1993 • 70 citations

Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines.

1996 • 49 citations

Regulation of the p53 pathway by Ras, the plot thickens

2001 • 36 citations

Receptor protein tyrosine kinase DDR is up‐regulated by p53 protein

1996 • 35 citations

The genomic structure of discoidin receptor tyrosine kinase.

1996 • 35 citations

A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain.

1993 • 29 citations

Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion

2000 • 15 citations